ES8101038A1 - Un procedimiento para la preparacion de isomeros opticos de labetalol (r,r) - Google Patents

Un procedimiento para la preparacion de isomeros opticos de labetalol (r,r)

Info

Publication number
ES8101038A1
ES8101038A1 ES484208A ES484208A ES8101038A1 ES 8101038 A1 ES8101038 A1 ES 8101038A1 ES 484208 A ES484208 A ES 484208A ES 484208 A ES484208 A ES 484208A ES 8101038 A1 ES8101038 A1 ES 8101038A1
Authority
ES
Spain
Prior art keywords
glaucoma
treatment
salicylamide
phenylpropyl
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES484208A
Other languages
English (en)
Other versions
ES484208A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ZA00794872A external-priority patent/ZA794872B/xx
Application filed by Schering Corp filed Critical Schering Corp
Publication of ES484208A0 publication Critical patent/ES484208A0/es
Publication of ES8101038A1 publication Critical patent/ES8101038A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE ISOMEROS OPTICOS DE LABETALOL (R,R) N, O-PROTEGIDO O SAL DE ADICION DEL MISMO POR HIDROGENOLISIS, LA CUAL SE EFECTUA POR MEDIO DE HIDROGENO Y PALADIO SOBRE CARBON. EL ISOMERO RESULTANTE (R,R) SE AISLA COMO BASE LIBRE O SAL DE ADICION DEL ACIDO. EL ATOMO DE NITRGENO BASICO Y EL GRUPO HIDROXI FENOLICO ESTAN PROTEGIDOS, SIENDO LOS GRUPOS PROTECTORES N- U O-BENCIL, N- U O-BENCILOXICARBONILO O N-TRICLOROETOXICARBONILO, O GRUPOS BENCILO. TRATAMIENTO DE ARRITMIA, HIPERTENSION Y ANGINA PECTORAL.
ES484208A 1978-09-20 1979-09-17 Un procedimiento para la preparacion de isomeros opticos de labetalol (r,r) Expired ES8101038A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94451678A 1978-09-20 1978-09-20
ZA00794872A ZA794872B (en) 1978-09-20 1979-09-13 A phenylalkylaminoethylsalicylamide,its preparation and pharmaceutical compositions containing it

Publications (2)

Publication Number Publication Date
ES484208A0 ES484208A0 (es) 1980-12-01
ES8101038A1 true ES8101038A1 (es) 1980-12-01

Family

ID=27130206

Family Applications (1)

Application Number Title Priority Date Filing Date
ES484208A Expired ES8101038A1 (es) 1978-09-20 1979-09-17 Un procedimiento para la preparacion de isomeros opticos de labetalol (r,r)

Country Status (2)

Country Link
US (1) US4312863A (es)
ES (1) ES8101038A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4558066A (en) * 1984-05-17 1985-12-10 Syntex (U.S.A.) Inc. Treatment and prevention of ocular hypertension

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4012444A (en) * 1969-07-08 1977-03-15 Allen & Hanburys Limited 5-[1-Hydroxy-2-(1-methyl-3-phenylpropyl)aminoethyl] salicylamide and physiologically acceptable acid addition salts thereof
JPS51128937A (en) * 1975-04-17 1976-11-10 Scherico Ltd Diastereomer of phenylaminoethanol derivatives
US4173583A (en) * 1975-04-17 1979-11-06 Schering Corporation Diastereoisomers of 5-(1-hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl)salicylamide
US4127674A (en) * 1977-03-21 1978-11-28 Allergan Pharmaceuticals, Inc. Method of treatment for glaucoma

Also Published As

Publication number Publication date
ES484208A0 (es) 1980-12-01
US4312863A (en) 1982-01-26

Similar Documents

Publication Publication Date Title
AU560189B2 (en) Treatment of ocular hypertension and glaucoma
AU1391683A (en) Treatment of ocular hypertension and glaucoma
AU540410B2 (en) Compositions and treatment utilizing anionic surfactants
GB2007091B (en) Ophthalmic preparations and process for producing the same
AU577295B2 (en) Composition and method for improved delivery of plant
EP0185390A3 (en) Tripeptidyl-argininaldehyde, process for its preparation and medicaments thereof, as well as n-(monoalkyl) and n,n-di-(alkyl)-xxx-l-proline dipeptide
MY106109A (en) 3-arylcarbonyl-1-aminoalkyl-1h-indole-containing antiglaucoma compositions
AU1531588A (en) Ophthalmic compositions and process for preparing
JO1073B1 (en) Gas treatment
AU518814B2 (en) Glaucoma treatment
AU528732B2 (en) Preparation of 4-hydroxy-5-alkyl and 2, 5-dialkyl-3-oxo-2h-furans
DE2860018D1 (en) Antithrombotic medicative combination and process for its preparation
AU5826780A (en) Tanning processes and compositions
ES8101038A1 (es) Un procedimiento para la preparacion de isomeros opticos de labetalol (r,r)
EP0003304A3 (en) N-substituted 2,6-dialkyl anilines and a process for the preparation of n-substituted 2,6-dialkyl anilines
AU517075B2 (en) Process for preparation of l-aspartic and n-thiocarboxyanhydride
AU510163B2 (en) Treatment of bovine mastitis
JPS53141241A (en) N-p-aminobenzyl-n'-p-aminophenylurea and process for its preparation
JPS5651413A (en) Glaucoma treatment
AU538599B2 (en) Compositions and treatment for hypertension
SU572459A1 (ru) 4-(2-Арилиден-1-метилгидразино-1)фталазоны, про вл ющие антигельминтную активность и способ их получени
AU1966988A (en) Ophthalmic agent and related compositions and method for treatment of the cornea
AU547036C (en) Compositions and process for permanent deformation of hair
AU547036B2 (en) Compositions and process for permanent deformation of hair
AU532669B2 (en) Agents for and processes of soaking hides