Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scherico Ltd
Original Assignee
Scherico Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ZA792044Aexternal-prioritypatent/ZA792044B/xx
Application filed by Scherico LtdfiledCriticalScherico Ltd
Publication of ES8100269A1publicationCriticalpatent/ES8100269A1/es
Publication of ES480178A0publicationCriticalpatent/ES480178A0/es
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE 1-FENIL-2, 3, 4, 5-TETRAHIDRO-1H-3-BENZAZEPINAS SUSTITUIDAS. CONSTA DE LAS SIGUIENTES ETAPAS: 1. REACCION DE UNA 7-X-8-HIDROXI-1-FENIL-2, 3, 4, 5-TETRAHIDRO-1H-BENZAZEPINA (SIENDO X FLUOR, CLORO, BROMO, TRIFLUOROMETILO O METILO) CON UNA AMINA MONOSUSTITUIDA O DISUSTITUIDA DE FORMULA (EN QUE R1 ES HIDROGENO, ALQUILO, ARALQUILO, ARILO, HIDROALQUILO, ALCOXIALQUILO O AMINOALQUILO; R2 ES HIDROGENO); OBTENIENDOSE EL COMPUESTO RESULTANTE. 2. OPCIONALMENTE SE PUEDEN EFECTUAR LAS SIGUIENTES OPERACIONES: A), ALQUILACION; B), AISLAMIENTO DEL ISOMERO (R) Y/O (S) DE UN RACEMATO ASI OBTENIDO; C, TRANSFORMACION DEL COMPUESTO OBTENIDO EN SU SAL DE ADICION DE ACIDO; D), LIBERACION DEL COMPUESTO DE SU SAL DE ADICION DE ACIDO. NEUROLEPTICOS, ANTIDEPRESIVOS, ANTIAGRESIVOS. *FORMULA*
ES480178A1978-05-081979-05-03Procedimiento para la preparacion de 1-fenil-2,3,4,5-tetrahidro-1h-3-benzazepinas
GrantedES480178A0
(es)