ES528452A0 - PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES DIETILAMINOALCOXIBENZOLES AND ITS ADDITIONAL SALTS ACID AND QUATERNARY AMMONIA - Google Patents
PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES DIETILAMINOALCOXIBENZOLES AND ITS ADDITIONAL SALTS ACID AND QUATERNARY AMMONIAInfo
- Publication number
- ES528452A0 ES528452A0 ES528452A ES528452A ES528452A0 ES 528452 A0 ES528452 A0 ES 528452A0 ES 528452 A ES528452 A ES 528452A ES 528452 A ES528452 A ES 528452A ES 528452 A0 ES528452 A0 ES 528452A0
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- dietilaminoalcoxibenzoles
- procedure
- new derivatives
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C217/06—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
- C07C217/14—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring
- C07C217/18—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Saccharide Compounds (AREA)
Abstract
The invention relates to the preparation of new diethylaminoalkoxybenzhydrol derivatives of the formula (I) <IMAGE> (I) wherein R1 is hydrogen, halogen, trihalomethyl, alkyl having from one to 4 carbon atoms or alkoxy having from one to 4 carbon atoms, R2 is halogen, trihalomethyl, or alkoxy having from one to 4 carbon atoms, and n is 1, 2, 3 or 4, and acid addition and quaternary ammonium salts thereof. According to another aspect of the invention, there are provided new compounds of the formula (I), and acid addition and quaternary salts thereof. The compounds can be used for the treatment of acute ethanolic intoxication and depression syndromes. Pharmaceutical compositions containing them as active ingredient are also within the scope of the invention.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU824182A HU187204B (en) | 1982-12-28 | 1982-12-28 | Process for producing new diethyl-amino-alkoxy-benzhydrol derivatives, acid additional salts, and quaternary salts and pharmaceutical compositions contatining them |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8600202A1 ES8600202A1 (en) | 1985-10-01 |
ES528452A0 true ES528452A0 (en) | 1985-10-01 |
Family
ID=10967233
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES528452A Granted ES528452A0 (en) | 1982-12-28 | 1983-12-27 | PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES DIETILAMINOALCOXIBENZOLES AND ITS ADDITIONAL SALTS ACID AND QUATERNARY AMMONIA |
ES543786A Granted ES543786A0 (en) | 1982-12-28 | 1985-06-01 | PROCEDURE FOR THE PREPARATION OF NEW A-ETILBEN-ZOL DERIVATIVES WITH A SUBSTITUTED DIETHYLAMINOALCOXY GROUP AND ITS ADDITIONAL SALTS ACIDIC AND QUATERNARY AMMONICS |
ES543785A Expired ES8605760A1 (en) | 1982-12-28 | 1985-06-01 | (Omega-(diethylamino)-alkoxy)-alpha-(ethyl)-benzhydrol derivatives, their acid addition salts and quaternary salts, process for their preparation and medicines containing these compounds. |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES543786A Granted ES543786A0 (en) | 1982-12-28 | 1985-06-01 | PROCEDURE FOR THE PREPARATION OF NEW A-ETILBEN-ZOL DERIVATIVES WITH A SUBSTITUTED DIETHYLAMINOALCOXY GROUP AND ITS ADDITIONAL SALTS ACIDIC AND QUATERNARY AMMONICS |
ES543785A Expired ES8605760A1 (en) | 1982-12-28 | 1985-06-01 | (Omega-(diethylamino)-alkoxy)-alpha-(ethyl)-benzhydrol derivatives, their acid addition salts and quaternary salts, process for their preparation and medicines containing these compounds. |
Country Status (14)
Country | Link |
---|---|
US (1) | US4605672A (en) |
EP (1) | EP0115080B1 (en) |
JP (1) | JPS59130842A (en) |
AT (1) | ATE19236T1 (en) |
AU (2) | AU557898B2 (en) |
CA (1) | CA1220225A (en) |
DE (1) | DE3363105D1 (en) |
DK (1) | DK163144C (en) |
ES (3) | ES528452A0 (en) |
FI (1) | FI78458C (en) |
GR (1) | GR78772B (en) |
HU (1) | HU187204B (en) |
IL (1) | IL70550A (en) |
ZA (1) | ZA839613B (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0084292B1 (en) * | 1981-12-14 | 1985-02-13 | Sandoz Ag | N,n-disubstituted alkenamides and phenylalkenamides, processes for their production and their use as pharmaceuticals |
AU589967B2 (en) * | 1985-06-11 | 1989-10-26 | Warner-Lambert Company | Improved process for the manufacture of diphenhydramine |
DK368687A (en) * | 1986-11-21 | 1988-05-22 | Cheminova As | AMINOALCYLED HYDROXY COMPOUNDS AND THEIR USE AS FUNGICIDES |
CA2016738A1 (en) * | 1989-06-08 | 1990-12-08 | Philippe Guerry | Substituted aminoalkylbenzene derivatives |
CA2020888A1 (en) * | 1989-07-27 | 1991-01-28 | Philippe Guerry | Substituted aminoalkoxybenzene derivatives |
US5214046A (en) * | 1989-07-27 | 1993-05-25 | Hoffmann-La Roche Inc. | Substituted aminoalkoxybenzene anti-fungicidal compositions and use |
GB9303210D0 (en) * | 1993-02-17 | 1993-03-31 | Univ Manitoba | Cancer treatment |
DE10225692A1 (en) * | 2002-06-10 | 2003-12-24 | Zimmer Ag | Process for the production of caprolactam from waste containing polyamide |
DE10333539A1 (en) * | 2003-07-23 | 2005-02-24 | Zimmer Ag | Process for the purification of caprolactam from waste containing polyamide by means of UV irradiation |
DE10333538B4 (en) * | 2003-07-23 | 2008-04-10 | Lurgi Zimmer Gmbh | Process for the treatment of polyamide-containing waste with the recycling of the Depolymerisationsrückstandes |
EP1754769A1 (en) | 2005-08-16 | 2007-02-21 | Research Institute of Petroleum | Continuous catalyst /wax separation method |
US7858825B2 (en) * | 2007-02-15 | 2010-12-28 | Colorado State University Research Foundation | Acid and base stable diphenylmethanol derivatives and methods of use |
US9861654B2 (en) * | 2012-09-06 | 2018-01-09 | Mcpharma Biotech Inc. | Treatment of diarrhea and post-weaning diarrhea with resistant potato starch |
WO2023106973A1 (en) * | 2021-12-10 | 2023-06-15 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Novel hepatoprotective agents |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3075014A (en) * | 1960-06-14 | 1963-01-22 | Richardson Merrell Inc | Basic substituted alkoxy diphenylalkanols, diphenylalkenes and diphenylalkanes |
US3927128A (en) * | 1971-01-18 | 1975-12-16 | Hoffmann La Roche | Tricyclic amines and processes for the preparation thereof |
US4094908A (en) * | 1973-08-15 | 1978-06-13 | Richter Gedeon Vegyeszeti Gyar Rt. | Alpha-substituted benzhydrol derivatives |
HU168432B (en) * | 1973-08-15 | 1976-04-28 | ||
US4024282A (en) * | 1975-11-25 | 1977-05-17 | Mitsubishi Chemical Industries Ltd. | Pharmaceutically active 2-(3-alkylaminopropoxy)diphenylmethanes |
-
1982
- 1982-12-28 HU HU824182A patent/HU187204B/en not_active IP Right Cessation
-
1983
- 1983-12-23 AU AU22907/83A patent/AU557898B2/en not_active Ceased
- 1983-12-23 CA CA000444203A patent/CA1220225A/en not_active Expired
- 1983-12-23 AU AU22905/83A patent/AU557954B2/en not_active Ceased
- 1983-12-27 JP JP58244942A patent/JPS59130842A/en active Granted
- 1983-12-27 IL IL8370550A patent/IL70550A/en unknown
- 1983-12-27 DK DK602283A patent/DK163144C/en not_active IP Right Cessation
- 1983-12-27 US US06/565,912 patent/US4605672A/en not_active Expired - Fee Related
- 1983-12-27 ES ES528452A patent/ES528452A0/en active Granted
- 1983-12-27 ZA ZA839613A patent/ZA839613B/en unknown
- 1983-12-27 FI FI834790A patent/FI78458C/en not_active IP Right Cessation
- 1983-12-28 AT AT83113176T patent/ATE19236T1/en not_active IP Right Cessation
- 1983-12-28 DE DE8383113176T patent/DE3363105D1/en not_active Expired
- 1983-12-28 GR GR73370A patent/GR78772B/el unknown
- 1983-12-28 EP EP83113176A patent/EP0115080B1/en not_active Expired
-
1985
- 1985-06-01 ES ES543786A patent/ES543786A0/en active Granted
- 1985-06-01 ES ES543785A patent/ES8605760A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES8600202A1 (en) | 1985-10-01 |
US4605672A (en) | 1986-08-12 |
AU557954B2 (en) | 1987-01-15 |
ZA839613B (en) | 1985-02-27 |
FI834790A0 (en) | 1983-12-27 |
DK163144B (en) | 1992-01-27 |
FI78458C (en) | 1989-08-10 |
IL70550A (en) | 1986-11-30 |
DK602283A (en) | 1984-06-29 |
DK602283D0 (en) | 1983-12-27 |
DK163144C (en) | 1992-06-22 |
JPH0159263B2 (en) | 1989-12-15 |
JPS59130842A (en) | 1984-07-27 |
CA1220225A (en) | 1987-04-07 |
EP0115080B1 (en) | 1986-04-16 |
AU557898B2 (en) | 1987-01-15 |
ES8603810A1 (en) | 1986-01-01 |
HU187204B (en) | 1985-11-28 |
ES8605760A1 (en) | 1986-04-01 |
FI78458B (en) | 1989-04-28 |
ATE19236T1 (en) | 1986-05-15 |
DE3363105D1 (en) | 1986-05-22 |
ES543786A0 (en) | 1986-01-01 |
EP0115080A1 (en) | 1984-08-08 |
IL70550A0 (en) | 1984-03-30 |
ES543785A0 (en) | 1986-04-01 |
FI834790A (en) | 1984-06-29 |
AU2290783A (en) | 1984-07-05 |
GR78772B (en) | 1984-10-02 |
AU2290583A (en) | 1984-07-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES528452A0 (en) | PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES DIETILAMINOALCOXIBENZOLES AND ITS ADDITIONAL SALTS ACID AND QUATERNARY AMMONIA | |
ES528462A0 (en) | PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES DIALQUILAMINOALCOXIBENCILALCOHOLICOS AND THEIR ADDITIONAL SALTS ACID AND QUATERNARY AMMONIA | |
ES543799A0 (en) | PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES 1-HYDROXY- PROPYLRESORCINES PROVIDED WITH A SUBSTITUTED PHENYLUS GROUP | |
ES543798A0 (en) | PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES 4-HYDROXY- -A-ETIL-BENZOLES | |
ES543801A0 (en) | PROCEDURE FOR THE PREPARATION OF NEW A-ETILBEN-ZOL DERIVATIVES WITH A SUBSTITUTED AMINOPROPANOLIC GROUP AND ITS ADDITIONAL SALTS ACIDAL AND QUATERNARY AMMONICS |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970303 |