ES507995A0 - Un procedimiento para la preparacion de un compuesto de pirimidoquinazolina. - Google Patents

Un procedimiento para la preparacion de un compuesto de pirimidoquinazolina.

Info

Publication number
ES507995A0
ES507995A0 ES507995A ES507995A ES507995A0 ES 507995 A0 ES507995 A0 ES 507995A0 ES 507995 A ES507995 A ES 507995A ES 507995 A ES507995 A ES 507995A ES 507995 A0 ES507995 A0 ES 507995A0
Authority
ES
Spain
Prior art keywords
carboxy
chem
alkyl
hydrogen
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES507995A
Other languages
English (en)
Other versions
ES8207539A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of ES8207539A1 publication Critical patent/ES8207539A1/es
Publication of ES507995A0 publication Critical patent/ES507995A0/es
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/121,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/141,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/241,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
    • C07D265/26Two oxygen atoms, e.g. isatoic anhydride
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/95Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C07D239/96Two oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES507995A 1979-12-03 1981-12-15 Un procedimiento para la preparacion de un compuesto de pirimidoquinazolina. Granted ES507995A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7941607 1979-12-03
GB8031965 1980-10-03

Publications (2)

Publication Number Publication Date
ES8207539A1 ES8207539A1 (es) 1982-10-01
ES507995A0 true ES507995A0 (es) 1982-10-01

Family

ID=26273769

Family Applications (4)

Application Number Title Priority Date Filing Date
ES497426A Expired ES8205202A1 (es) 1979-12-03 1980-12-03 Un procedimiento para preparar un compuesto de quinazolina
ES507996A Expired ES8207540A1 (es) 1979-12-03 1981-12-15 Un procedimiento para la preparacion de un compuesto de pirimidoquinazolina.
ES507995A Granted ES507995A0 (es) 1979-12-03 1981-12-15 Un procedimiento para la preparacion de un compuesto de pirimidoquinazolina.
ES507994A Expired ES8301234A1 (es) 1979-12-03 1981-12-15 Un procedimiento para la preparacion de un compuesto de quinazolina.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES497426A Expired ES8205202A1 (es) 1979-12-03 1980-12-03 Un procedimiento para preparar un compuesto de quinazolina
ES507996A Expired ES8207540A1 (es) 1979-12-03 1981-12-15 Un procedimiento para la preparacion de un compuesto de pirimidoquinazolina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES507994A Expired ES8301234A1 (es) 1979-12-03 1981-12-15 Un procedimiento para la preparacion de un compuesto de quinazolina.

Country Status (10)

Country Link
US (2) US4377580A (es)
EP (1) EP0030156B1 (es)
JP (1) JPH0651686B2 (es)
AT (1) ATE6778T1 (es)
AU (1) AU541811B2 (es)
DE (1) DE3067201D1 (es)
DK (1) DK513980A (es)
ES (4) ES8205202A1 (es)
GR (1) GR71637B (es)
IE (1) IE51802B1 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3046366A1 (de) * 1980-12-09 1982-07-08 Bayer Ag, 5090 Leverkusen Tricyclische cytosinderivate zur verwendung in arzneimitteln und verfahren zu ihrer herstellung
JPS608274A (ja) * 1983-06-27 1985-01-17 Fujisawa Pharmaceut Co Ltd 新規キナゾリノン誘導体およびその製造法・並びに抗アレルギ−剤
NO162019C (no) * 1983-11-23 1989-10-25 Fujisawa Pharmaceutical Co Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater.
US5420133A (en) * 1993-03-19 1995-05-30 Merck & Co., Inc. Quinazolinones substituted with phenoxyphenylacetic acid derivatives
JP5236293B2 (ja) 2005-01-13 2013-07-17 ブリストル−マイヤーズ スクイブ カンパニー Xia因子阻害剤としての置換ビアリール化合物
US8633186B2 (en) * 2007-06-08 2014-01-21 Senomyx Inc. Modulation of chemosensory receptors and ligands associated therewith
US9603848B2 (en) * 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
AU2013202912B2 (en) * 2007-06-08 2016-10-27 Firmenich Incorporated Modulation of chemosensory receptors and ligands associated therewith
US7928111B2 (en) * 2007-06-08 2011-04-19 Senomyx, Inc. Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors
US8586733B2 (en) 2008-07-31 2013-11-19 Senomyx, Inc. Processes and intermediates for making sweet taste enhancers
RU2511315C2 (ru) 2008-07-31 2014-04-10 Синомикс, Инк. Композиции, содержащие усилители сладкого вкуса, и способы их получения
US9000054B2 (en) 2010-08-12 2015-04-07 Senomyx, Inc. Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer
RU2014149684A (ru) 2012-05-31 2016-07-20 Ф. Хоффманн-Ля Рош Аг Производные аминохиназолина и пиридопиримидина
KR20150041040A (ko) 2012-08-06 2015-04-15 세노믹스, 인코포레이티드 단맛 향미 개질제
JO3155B1 (ar) 2013-02-19 2017-09-20 Senomyx Inc معدِّل نكهة حلوة
US11945813B2 (en) 2018-08-07 2024-04-02 Firmenich Incorporated 5-substituted 4-amino-1H-benzo[c][1,2,6]thiadiazine 2,2-dioxides and formulations and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1086666A (en) * 1966-09-12 1967-10-11 Wander Ag Dr A Novel 6-p-tolyl-2,3,6,7-tetrahydro-4h-pyrimido-[1,2-c] quinazoline
US3594379A (en) * 1968-09-16 1971-07-20 Sandoz Ag 2,3-dihydroimidazo(1,2-c)quinazolines
BE759842R (fr) 1969-12-05 1971-06-03 Sandoz Sa Nouveaux derives de la 4-amino-quinazoline, leur preparation etmedicaments contenant ces
CA986932A (en) * 1970-08-27 1976-04-06 Shigeho Inaba Process for preparing quinazoline derivatives
US4167569A (en) * 1976-12-09 1979-09-11 Imperial Chemical Industries Limited Pyrimido[1,2-a ]benzimidazole derivatives
US4105766A (en) * 1977-08-19 1978-08-08 Sterling Drug Inc. 4,5-Dihydro-5-oxopyrazolo[1,5-a]quinazoline-3-carboxylic acid derivatives
US4192944A (en) * 1978-04-03 1980-03-11 Bristol-Myers Company Optionally substituted 4-oxo-4H-pyrido[1,2-a]pyrimidine-3-N-(1H-tetrazol-4-yl)carboxamides and their use as antiallergy agents

Also Published As

Publication number Publication date
EP0030156B1 (en) 1984-03-21
JPH0651686B2 (ja) 1994-07-06
ES507996A0 (es) 1982-10-01
ES507994A0 (es) 1982-11-16
EP0030156A1 (en) 1981-06-10
ATE6778T1 (de) 1984-04-15
ES8207539A1 (es) 1982-10-01
AU541811B2 (en) 1985-01-24
JPH05294946A (ja) 1993-11-09
AU6473380A (en) 1981-06-11
GR71637B (es) 1983-06-20
ES8301234A1 (es) 1982-11-16
ES497426A0 (es) 1982-06-01
ES8205202A1 (es) 1982-06-01
ES8207540A1 (es) 1982-10-01
US4543356A (en) 1985-09-24
DE3067201D1 (en) 1984-04-26
IE802421L (en) 1981-06-03
IE51802B1 (en) 1987-04-01
US4377580A (en) 1983-03-22
DK513980A (da) 1981-06-04

Similar Documents

Publication Publication Date Title
ES507996A0 (es) Un procedimiento para la preparacion de un compuesto de pirimidoquinazolina.
ES2070660B1 (es) Un procedimiento para la preparacion de 2,5-damino-3-hidroxihexanos sustituidos, utiles como inhibidores de proteasas retrovirales.
DK165244C (da) Analogifremgangsmaade til fremstilling af 1,2,3-trisubstituerede indoler
ES549629A0 (es) Un procedimiento para preparar derivados de dihidropiridazi-nona
ES525653A0 (es) Procedimiento para preparar nuevos diazabiciclo-(3.3.1)-nonanos
ES2037665T3 (es) Procedimiento para la preparacion de compuestos heterociclicos que contienen n.
ES525484A0 (es) Un procedimiento para obtener derivados de indanilbenzamida
ES545728A0 (es) Procedimiento para preparar 5h,11h-pirrolo (2,1c)-(1,4)ben- zoxazepinas sustituidas en posicion 11
ES8504723A1 (es) Un metodo para preparar derivados de 4-hidroxi-2-quinolonas.
ES2056194T3 (es) Compuestos tetraciclicos antidepresivos.
ES515872A0 (es) "procedimiento para la preparacion de nuevos derivados de acidos 4-fenoxialcarboxilicos sustituidos con radicales haterociclicos".
ES554636A0 (es) Un procedimiento para preparar derivados de vinilisoquinolina
ES528816A0 (es) Procedimiento de producir compuestos para el tratamiento de la hipertension
NO853551L (no) Fremgangsmaate ved fremstilling av prolinderivater og lignende forbindelser med antihypertensiv aktivitet.
ZA86543B (en) 2-alkoxycarbonylalkyl-3-oxo-5,6-diaryl-as-triazines having utility as therapeutics
ES548497A0 (es) Procedimiento para preparar compuestos de 3-amino-2,3-dihi- dro-1-benzoxepina
ES545870A0 (es) Procedimiento para preparar derivados de pirrolidindiona.
ES2039270T3 (es) Derivados de gamma-l-glutamil-4-nitroanilida y procedimiento para determinar actividad de gamma-gtp utilizandolos.