ES482484A1 - Novel taurine derivatives - Google Patents
Novel taurine derivativesInfo
- Publication number
- ES482484A1 ES482484A1 ES482484A ES482484A ES482484A1 ES 482484 A1 ES482484 A1 ES 482484A1 ES 482484 A ES482484 A ES 482484A ES 482484 A ES482484 A ES 482484A ES 482484 A1 ES482484 A1 ES 482484A1
- Authority
- ES
- Spain
- Prior art keywords
- taurine derivatives
- novel
- novel taurine
- derivatives
- ch2ch2or
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical class NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 title abstract 2
- -1 nicotinoyl Chemical group 0.000 abstract 3
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 230000002402 anti-lipaemic effect Effects 0.000 abstract 1
- 230000001989 choleretic effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
- Pyridine Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Novel taurine derivatives of general formula (I> < IMAGE > (wherein R<1> is nicotinoyl, 3,4,5- trimethoxybenzoyl or acetylsalicyloyl and R<2> is R<1> or -CH2CH2OR<1>) have antilipemic and choleretic activities, and are made by acylation methods.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT24587/78A IT1096662B (en) | 1978-06-15 | 1978-06-15 | TAURINIC DERIVATIVES FOR ANTI-LIPEMIC AND CHOLERETIC ACTIVITIES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM |
Publications (1)
Publication Number | Publication Date |
---|---|
ES482484A1 true ES482484A1 (en) | 1980-04-01 |
Family
ID=11214073
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES476812A Expired ES476812A1 (en) | 1978-06-15 | 1979-01-12 | Novel taurine derivatives |
ES482483A Expired ES482483A1 (en) | 1978-06-15 | 1979-07-13 | Novel taurine derivatives |
ES482484A Expired ES482484A1 (en) | 1978-06-15 | 1979-07-13 | Novel taurine derivatives |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES476812A Expired ES476812A1 (en) | 1978-06-15 | 1979-01-12 | Novel taurine derivatives |
ES482483A Expired ES482483A1 (en) | 1978-06-15 | 1979-07-13 | Novel taurine derivatives |
Country Status (9)
Country | Link |
---|---|
JP (2) | JPS5943942B2 (en) |
BE (1) | BE876969A (en) |
DE (1) | DE2901046C3 (en) |
ES (3) | ES476812A1 (en) |
FR (2) | FR2465717A1 (en) |
GB (1) | GB2023586B (en) |
IT (1) | IT1096662B (en) |
LU (1) | LU81379A1 (en) |
NL (1) | NL7904644A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1126575B (en) * | 1979-12-07 | 1986-05-21 | Causyth Chim Farm | COMPOUND WITH ANTI-INFLAMMATORY, ANALGESIC AND ANTI-PIRETIC ACTIVITY, PROCESS FOR ITS PREPARATION, AND RELATED PHARMACEUTICAL COMPOSITIONS |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB586453A (en) * | 1944-08-01 | 1947-03-19 | Ward Blenkinsop & Co Ltd | Process for the production of derivatives of nicotinic acid |
FR920312A (en) * | 1944-08-01 | 1947-04-03 | Ward | Process for the preparation of nicotic acid derivatives |
CH520697A (en) * | 1970-03-03 | 1972-03-31 | Sopharma Sa | Process for the preparation of a nicotinic acid ester-amide |
-
1978
- 1978-06-15 IT IT24587/78A patent/IT1096662B/en active
-
1979
- 1979-01-11 FR FR7900641A patent/FR2465717A1/en active Pending
- 1979-01-12 DE DE2901046A patent/DE2901046C3/en not_active Expired
- 1979-01-12 ES ES476812A patent/ES476812A1/en not_active Expired
- 1979-06-13 NL NL7904644A patent/NL7904644A/en not_active Application Discontinuation
- 1979-06-13 JP JP54075148A patent/JPS5943942B2/en not_active Expired
- 1979-06-14 LU LU81379A patent/LU81379A1/en unknown
- 1979-06-14 BE BE2/57867A patent/BE876969A/en not_active IP Right Cessation
- 1979-06-15 GB GB7920953A patent/GB2023586B/en not_active Expired
- 1979-07-13 ES ES482483A patent/ES482483A1/en not_active Expired
- 1979-07-13 ES ES482484A patent/ES482484A1/en not_active Expired
-
1982
- 1982-08-11 FR FR8214014A patent/FR2511365A1/en active Granted
-
1983
- 1983-12-16 JP JP23774083A patent/JPS6133171A/en active Pending
Also Published As
Publication number | Publication date |
---|---|
GB2023586B (en) | 1982-08-04 |
IT1096662B (en) | 1985-08-26 |
JPS5943942B2 (en) | 1984-10-25 |
GB2023586A (en) | 1980-01-03 |
JPS6133171A (en) | 1986-02-17 |
BE876969A (en) | 1979-10-01 |
DE2901046C3 (en) | 1982-05-06 |
LU81379A1 (en) | 1979-09-12 |
IT7824587A0 (en) | 1978-06-15 |
NL7904644A (en) | 1979-12-18 |
DE2901046B2 (en) | 1981-07-16 |
FR2511365B1 (en) | 1985-03-15 |
ES476812A1 (en) | 1979-12-16 |
FR2511365A1 (en) | 1983-02-18 |
ES482483A1 (en) | 1980-04-16 |
JPS554381A (en) | 1980-01-12 |
FR2465717A1 (en) | 1981-03-27 |
DE2901046A1 (en) | 1979-12-20 |
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