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Sandoz AG
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Sandoz AG
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Publication of ES471126A1publicationCriticalpatent/ES471126A1/en
Process for preparing isoindoline derivatives, of formula Ia, ** (Formula 01) ** where R1 is hydrogen, fluorine, chlorine, bromine, alkyl of 1 to 4 carbon atoms or alkoxy of 1 to 4 carbon atoms, R2 is hydrogen or alkyl of 1 to 4 carbon atoms, R''3 is alkyl of 1 or 2 carbon atoms, and its acid addition salts, characterized in that it comprises dehydrating compounds of formula II ** (Formula 02) ** wherein R1, R2 and R''3 are defined as above, such as in a strong mineral or organic acid, conveniently at a temperature between ambient and reflux, and, if desired, the resulting compounds are converted of formula Ia in its acid addition salts. (Machine-translation by Google Translate, not legally binding)
ES471126A1977-06-281978-06-26Procedure for preparing isoindoline derivatives (Machine-translation by Google Translate, not legally binding)
ExpiredES471126A1
(en)
Procedure for preparation of new derivatives of 1,3dihidro-3-1-2-2-3-dihydro-1,4-benzodioxin-2-il-2-hidroxi etil-piperidin-4-il-2H-indol-2 -ona (Machine-translation by Google Translate, not legally binding)