ES464943A1 - Procedure for the obtaining of amidas of pharmacological interest. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the obtaining of amidas of pharmacological interest. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES464943A1
ES464943A1 ES464943A ES464943A ES464943A1 ES 464943 A1 ES464943 A1 ES 464943A1 ES 464943 A ES464943 A ES 464943A ES 464943 A ES464943 A ES 464943A ES 464943 A1 ES464943 A1 ES 464943A1
Authority
ES
Spain
Prior art keywords
alkoxy
translation
carbon atoms
equal
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES464943A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorio Fides SA
Original Assignee
Laboratorios Martin Cuatrecasas SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorios Martin Cuatrecasas SA filed Critical Laboratorios Martin Cuatrecasas SA
Priority to ES464943A priority Critical patent/ES464943A1/en
Publication of ES464943A1 publication Critical patent/ES464943A1/en
Expired legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Procedure for obtaining amides of pharmacological interest of structural formula: *** (See formula 1) in which Y can be located in any of the 2', 3', 4', or 5' positions of the benzene ring and is the same to hydroxylohaloalkyl with a number of carbon atoms from 1 to 4o alkoxy also with a number of carbon atoms from 1 to 4; n equals 12 or 3; R equal to R'which in turn is equal to H or bond; R'' equal to HCH2CX3 (where X is a halogen) CH2C6H4X'(where X' is an alkoxy or nitro halogen hydrogen) or CH (C6H5) 2C (C6H5) 3 lower alkyls with a number of carbon atoms 1 to 4 adamantylCH2-CO-C6H4X'' (where X'' is a halogen, alkoxy or nitro hydrogen) SnR3 (where R is an inferoaryl or aryl alcohol group) SiR'3 (where R'is an alcohol group inferioaryl or aryl alcohol) which is characterized by the fact that said amides are obtained by the action of a dehydrating agent on the aminobenzoic acid whose carboxyl group is protected and the corresponding cinnamic acid within an inert solvent and with the subsequent deprotection of the carboxyl group. (Machine-translation by Google Translate, not legally binding)
ES464943A 1977-12-10 1977-12-10 Procedure for the obtaining of amidas of pharmacological interest. (Machine-translation by Google Translate, not legally binding) Expired ES464943A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES464943A ES464943A1 (en) 1977-12-10 1977-12-10 Procedure for the obtaining of amidas of pharmacological interest. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES464943A ES464943A1 (en) 1977-12-10 1977-12-10 Procedure for the obtaining of amidas of pharmacological interest. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES464943A1 true ES464943A1 (en) 1978-09-01

Family

ID=8475062

Family Applications (1)

Application Number Title Priority Date Filing Date
ES464943A Expired ES464943A1 (en) 1977-12-10 1977-12-10 Procedure for the obtaining of amidas of pharmacological interest. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES464943A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000006153A1 (en) * 1998-07-28 2000-02-10 Smithkline Beecham Corporation Propenamides as ccr5 modulators
CN104693063A (en) * 2015-03-18 2015-06-10 中国药科大学制药有限公司 Synthesis method of tranilast

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000006153A1 (en) * 1998-07-28 2000-02-10 Smithkline Beecham Corporation Propenamides as ccr5 modulators
CN104693063A (en) * 2015-03-18 2015-06-10 中国药科大学制药有限公司 Synthesis method of tranilast

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