ES459087A1 - Substituted acetylenic compounds - Google Patents

Substituted acetylenic compounds

Info

Publication number
ES459087A1
ES459087A1 ES459087A ES459087A ES459087A1 ES 459087 A1 ES459087 A1 ES 459087A1 ES 459087 A ES459087 A ES 459087A ES 459087 A ES459087 A ES 459087A ES 459087 A1 ES459087 A1 ES 459087A1
Authority
ES
Spain
Prior art keywords
formula
compounds
acetylenic compounds
substituted acetylenic
aralkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES459087A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of ES459087A1 publication Critical patent/ES459087A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
    • C07C1/26—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only halogen atoms as hetero-atoms
    • C07C1/30—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon starting from organic compounds containing only halogen atoms as hetero-atoms by splitting-off the elements of hydrogen halide from a single molecule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/25—Preparation of halogenated hydrocarbons by splitting-off hydrogen halides from halogenated hydrocarbons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C25/00—Compounds containing at least one halogen atom bound to a six-membered aromatic ring
    • C07C25/24—Halogenated aromatic hydrocarbons with unsaturated side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/65—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by splitting-off hydrogen atoms or functional groups; by hydrogenolysis of functional groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The compounds of formula I, in which R<1> is H, alkyl, aralkyl or diaralkyl, R<2> is H or a halogen and R<3> is H, alkyl, aralkyl, aryl, aryloxy, benzoyl or 2-thienocarbonyl, R<2> and R<3> not being simultaneously H, are obtained by halogenation of a ketone of formula II, followed by dehydrohalogenation of the intermediate halogenated derivative of formula III by means of a strong base. The compounds of formula I are useful as intermediates for the preparation of pharmaceutically active compounds.
ES459087A 1976-05-25 1977-05-24 Substituted acetylenic compounds Expired ES459087A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU76CI00001668A HU172938B (en) 1976-05-25 1976-05-25 Process for producing substituted phenyl-acethylenes

Publications (1)

Publication Number Publication Date
ES459087A1 true ES459087A1 (en) 1978-04-16

Family

ID=10994618

Family Applications (1)

Application Number Title Priority Date Filing Date
ES459087A Expired ES459087A1 (en) 1976-05-25 1977-05-24 Substituted acetylenic compounds

Country Status (9)

Country Link
JP (1) JPS52144633A (en)
CH (1) CH622485A5 (en)
DK (1) DK226977A (en)
ES (1) ES459087A1 (en)
GB (1) GB1581359A (en)
HU (1) HU172938B (en)
NL (1) NL7705680A (en)
SE (1) SE431867B (en)
SU (1) SU656499A3 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54109952A (en) * 1978-02-18 1979-08-29 Takayuki Shioiri 3**fluoroo4**phenylpropiophenone and its manufacture
JPS54128553A (en) * 1978-03-27 1979-10-05 Takayuki Shioiri Novel 3**benzoylpropiophenone and its manufacture
US4665246A (en) * 1984-03-09 1987-05-12 Chem Biochem Research, Inc. Method of producing ethynyl aromatic compounds
JP2003037511A (en) * 2001-07-26 2003-02-07 Niigata Seimitsu Kk Circuit for extracting weak signal
DK1675813T3 (en) 2003-10-13 2008-03-03 Serono Lab Process for the preparation of para-phenylalkynylbenzaldehydes

Also Published As

Publication number Publication date
SE7705840L (en) 1977-11-26
SU656499A3 (en) 1979-04-05
GB1581359A (en) 1980-12-10
NL7705680A (en) 1977-11-29
DK226977A (en) 1977-11-26
HU172938B (en) 1979-01-28
SE431867B (en) 1984-03-05
CH622485A5 (en) 1981-04-15
JPS52144633A (en) 1977-12-02

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971201