ES458163A1 - Procedimiento para preparar imidazolidina-2-onas y -2-tionas1,4-disustituidas - Google Patents
Procedimiento para preparar imidazolidina-2-onas y -2-tionas1,4-disustituidasInfo
- Publication number
- ES458163A1 ES458163A1 ES458163A ES458163A ES458163A1 ES 458163 A1 ES458163 A1 ES 458163A1 ES 458163 A ES458163 A ES 458163A ES 458163 A ES458163 A ES 458163A ES 458163 A1 ES458163 A1 ES 458163A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- phenyl
- alkoxy
- halo
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/42—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/38—One oxygen atom with acyl radicals or hetero atoms directly attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Procedimiento para preparar imidazolidina-2-onas 1,4-disustituidas, de fórmula **fórmula** donde R es hidrógeno, alquilo C1-C6, fenilo, fenilo sustituido con hasta tres grupos que consisten en alquilo C1-C6, alquilo C1-C6 halo-sustituido , alcoxi C1-C6 y una porción de la fórmula COR3, donde R3 es hidrógeno, alquilo C1-C6, alcoxi C1-C6, fenoxi, halo C1-C6, alquilo, fenilo o fenilo o fenoxi sustituido con hasta cuatro grupos que consisten en alquilo C1-C6, halo trifluormetilo o alcoxi C1-C6, R4 es alquilo C1-C6, alcoxi C1-C6, fenoxi, cicloalquilo C5-C10, fenilo o fenilo o fenoxi sustituido con hasta cuatro grupos que consisten en alquilo C1-C6, alcoxi C1-C6 , halo o trifluormetilo, R2 es fenilo o fenilo sustituido con hasta dos grupos que consisten en alquilo C1-C6, alcoxi C1-C6, halo o trifluormetilo, se reduce una imidazolinona de fórmula **fórmula** donde R, R2 y R4 son como se han definido anteriormente, por hidrogenación en presencia de un catalizador quiral, en un disolvente orgánico adecuado, a una temperatura desde aproximadamente 250º a 80ºC.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68030276A | 1976-04-26 | 1976-04-26 | |
| US05/739,923 US4087611A (en) | 1976-04-26 | 1976-11-08 | Optically active 1-oxyethyl-4-phenyl-2-imidazolidones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES458163A1 true ES458163A1 (es) | 1979-06-01 |
Family
ID=27102426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES458163A Expired ES458163A1 (es) | 1976-04-26 | 1977-04-26 | Procedimiento para preparar imidazolidina-2-onas y -2-tionas1,4-disustituidas |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS52131579A (es) |
| AR (1) | AR214311A1 (es) |
| AU (1) | AU2341177A (es) |
| DD (1) | DD131170A5 (es) |
| DE (1) | DE2718058A1 (es) |
| DK (1) | DK181077A (es) |
| ES (1) | ES458163A1 (es) |
| FR (1) | FR2371433A1 (es) |
| GB (1) | GB1580352A (es) |
| IL (1) | IL51639A0 (es) |
| IT (1) | IT1086594B (es) |
| NL (1) | NL7704251A (es) |
| NO (1) | NO771421L (es) |
| NZ (1) | NZ183577A (es) |
| SE (1) | SE7704744L (es) |
| SU (1) | SU791231A3 (es) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0604822D0 (en) * | 2006-03-09 | 2006-04-19 | Arakis Ltd | The treatment of inflammatory disorders and pain |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5010106A (es) * | 1973-05-24 | 1975-02-01 | ||
| JPS5225301B2 (es) * | 1973-11-16 | 1977-07-06 | ||
| IL51654A0 (en) * | 1976-04-26 | 1977-05-31 | American Cyanamid Co | New non-asymmetric synthesis of tetramisole levamisole and their derivatives |
-
1977
- 1977-03-10 IL IL51639A patent/IL51639A0/xx unknown
- 1977-03-11 NZ NZ183577A patent/NZ183577A/xx unknown
- 1977-03-17 GB GB10270/77A patent/GB1580352A/en not_active Expired
- 1977-03-18 AU AU23411/77A patent/AU2341177A/en not_active Expired
- 1977-03-25 AR AR266986A patent/AR214311A1/es active
- 1977-04-18 SU SU772470213A patent/SU791231A3/ru active
- 1977-04-19 NL NL7704251A patent/NL7704251A/xx not_active Application Discontinuation
- 1977-04-20 IT IT49033/77A patent/IT1086594B/it active
- 1977-04-22 DE DE19772718058 patent/DE2718058A1/de not_active Withdrawn
- 1977-04-25 NO NO771421A patent/NO771421L/no unknown
- 1977-04-25 SE SE7704744A patent/SE7704744L/xx unknown
- 1977-04-25 DK DK181077A patent/DK181077A/da not_active Application Discontinuation
- 1977-04-26 ES ES458163A patent/ES458163A1/es not_active Expired
- 1977-04-26 DD DD7700198606A patent/DD131170A5/xx unknown
- 1977-04-26 FR FR7712566A patent/FR2371433A1/fr active Pending
- 1977-04-26 JP JP4745577A patent/JPS52131579A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| NZ183577A (en) | 1980-03-05 |
| IL51639A0 (en) | 1977-05-31 |
| AU2341177A (en) | 1978-09-21 |
| DD131170A5 (de) | 1978-06-07 |
| IT1086594B (it) | 1985-05-28 |
| NL7704251A (nl) | 1977-10-28 |
| SE7704744L (sv) | 1977-10-27 |
| DK181077A (da) | 1977-10-27 |
| GB1580352A (en) | 1980-12-03 |
| DE2718058A1 (de) | 1977-11-17 |
| AR214311A1 (es) | 1979-05-31 |
| FR2371433A1 (fr) | 1978-06-16 |
| JPS52131579A (en) | 1977-11-04 |
| SU791231A3 (ru) | 1980-12-23 |
| NO771421L (no) | 1977-10-27 |
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