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Laboratorios Made SA
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Laboratorios Made SA
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Priority to ES428127ApriorityCriticalpatent/ES428127A1/es
Publication of ES428127A1publicationCriticalpatent/ES428127A1/es
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE ALFA-2,5,9-TRIMETIL-TIENO-(3,2-F)-MORFANO A PARTIR DEL MAGNESIANO DEL 2-CLOROMETIL-TIOFENO Y DEL YODURO DE 1,3,4-TRIMETIL-PIRIDINIO. MEDIANTE LOS REACTIVOS ANTERIORES POR TRATAMIENTO A REFLUJO SE OBTIENE EL 2-(2-TENIL)-1,3,4-TRIMETIL-1,2 DIHIDROPIRIDINA. ESTE PRODUCTO REACCIONA EN MEDIO BASICO CON TETRAHICLORURO DE BORO Y SODIO CONDUCIENDO AL 2-(2-TENIL)-1,3,4-TRIMETIL-1,2,5,6-TETRAHIDROPIRIDINA, QUE POR TRATAMIENTO CON ACIDO BROMHIDRICO CONDUCE A LA OBTENCION EL ALFA-2,5,9-TRIMETIL-TIENO-(3,2-F)-MORFANO. ESTOS PRODUCTOS TIENEN ACTIVIDAD ANALGESICA.
ES428127A1974-07-101974-07-10Un procedimiento para la obtencion de alfa-2,5,9-trimetil- tieno-(3,2-f)-morfano.
ExpiredES428127A1
(es)