ES424558A1 - Preparation of derivatives of penicillanic and cephalosporinic acids - Google Patents

Preparation of derivatives of penicillanic and cephalosporinic acids

Info

Publication number
ES424558A1
ES424558A1 ES424558A ES424558A ES424558A1 ES 424558 A1 ES424558 A1 ES 424558A1 ES 424558 A ES424558 A ES 424558A ES 424558 A ES424558 A ES 424558A ES 424558 A1 ES424558 A1 ES 424558A1
Authority
ES
Spain
Prior art keywords
group
see formula
general formula
formula
formulas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES424558A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto Luso Farmaco dItalia SpA
Original Assignee
Istituto Luso Farmaco dItalia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Luso Farmaco dItalia SpA filed Critical Istituto Luso Farmaco dItalia SpA
Publication of ES424558A1 publication Critical patent/ES424558A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

Procedure for obtaining carboxylic derivatives, of the general formula: **(See formula)** in which R1 represents a group: **(See formula)** R2 represents a group that has the general formula: **(See formula)** in which R3, R4 and R5 each represent a hydrogen atom or a methyl or ethyl group, and R6 represents a group: -CH3; -CH2-CH3 - (CH2) 2-CH3; -CH (CH3) 2; - (CH2) 3-CH3; -C (CH3) 3; -CH (CH2-CH3) 2 or **(See formula)** whose procedure comprises reacting a compound of the general formula: **(See formula)** in which formulas R1 has the meaning indicated above, R7 represents a methylene group and R8 represents an alkali or tertiary ammonium cation, with a compound of the general formula: **(See formula)** where R3, R4, R5 and R6 have the meanings indicated above, X represents a removable radical, such as a chlorine, bromine, or iodine atom, or an acyloxy or arylsulfonyl group, to obtain respectively a compound of the general formula: **(See formula)** in which formulas R1, R2 and R7 have the meanings indicated above, subjecting these compounds to selective acid hydrolysis, in order to produce the desired compounds, of formulas I, II or III, respectively. (Machine-translation by Google Translate, not legally binding)
ES424558A 1973-03-16 1974-03-15 Preparation of derivatives of penicillanic and cephalosporinic acids Expired ES424558A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PT5954173 1973-03-16

Publications (1)

Publication Number Publication Date
ES424558A1 true ES424558A1 (en) 1976-05-16

Family

ID=20081785

Family Applications (1)

Application Number Title Priority Date Filing Date
ES424558A Expired ES424558A1 (en) 1973-03-16 1974-03-15 Preparation of derivatives of penicillanic and cephalosporinic acids

Country Status (10)

Country Link
JP (1) JPS49125388A (en)
AR (1) AR207562A1 (en)
AT (1) AT343800B (en)
CA (1) CA1022159A (en)
DE (1) DE2412525A1 (en)
ES (1) ES424558A1 (en)
FR (1) FR2221456B3 (en)
GB (1) GB1449535A (en)
IT (1) IT1067250B (en)
ZA (1) ZA741758B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6894498B2 (en) * 2016-08-12 2021-06-30 ザ カトリック ユニバーシティ オブ コリア インダストリー−アカデミック コーオペレイション ファウンデーション Composition for soft tissue hardening

Also Published As

Publication number Publication date
FR2221456A1 (en) 1974-10-11
CA1022159A (en) 1977-12-06
ZA741758B (en) 1975-01-29
FR2221456B3 (en) 1976-12-31
JPS49125388A (en) 1974-11-30
IT1067250B (en) 1985-03-16
AT343800B (en) 1978-06-12
GB1449535A (en) 1976-09-15
ATA217974A (en) 1977-10-15
AR207562A1 (en) 1976-10-15
DE2412525A1 (en) 1974-09-26

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19861216