ES411188A1 - Procedimiento para la preparacion de eteres heterociclicos. - Google Patents
Procedimiento para la preparacion de eteres heterociclicos.Info
- Publication number
- ES411188A1 ES411188A1 ES411188A ES411188A ES411188A1 ES 411188 A1 ES411188 A1 ES 411188A1 ES 411188 A ES411188 A ES 411188A ES 411188 A ES411188 A ES 411188A ES 411188 A1 ES411188 A1 ES 411188A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- salts
- alkoxy
- transformed
- representing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/18—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyridine Compounds (AREA)
- Quinoline Compounds (AREA)
Abstract
Procedimiento para la preparación de éteres heterocíclicos de la fórmula I **fórmula** en la que R1 significa un sistema de anillo heterocíclico, nitrogenado, insaturado y de un único núcleo, que puede contener adicionalmente además un átomo de azufre y/o un anillo bencenico condensado con él, o puede estar sustituido por grupos alcohilo o alcoxi de bajo peso molecular, fenilalcohilo o fenilo, R2 significa un radical fenilo eventualmente sustituido por grupos alcohilo o alcoxi de bajo peso molecular , átomos de cloro o de bromo, que también puede contener en el anillo 1 a 2 átomos de nitrógeno, y A significa un radical alcohileno de cadena recta o ramificada con 2 hasta 6 átomos de carbono, así como sus sales por adición de ácido fisiológicamente compatibles, caracterizado se hacen reaccionar compuestos de la fórmula VII Y-NH2 (VII) con compuestos de la fórmula VIII **fórmula** preferiblemente en forma de sus ésteres susceptibles de reaccionar, representando siempre uno de los símbolos Y yZ el grupo R2 y representando el otro el grupo- A-O-R1; y eventualmente se transforman las sales así obtenidas en las bases libres o se transforman las bases en sus sales por adición de ácido.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19691946172 DE1946172A1 (de) | 1969-09-12 | 1969-09-12 | Neue heterocyclische AEther und Verfahren zu ihrer Herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ES411188A1 true ES411188A1 (es) | 1975-12-01 |
Family
ID=5745285
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES383564A Expired ES383564A1 (es) | 1969-09-12 | 1970-09-11 | Procedimiento para la preparacion de eteres heterociclicos. |
ES411189A Expired ES411189A1 (es) | 1969-09-12 | 1973-02-01 | Procedimiento para la preparacion de eteres heterociclicos. |
ES411187A Expired ES411187A1 (es) | 1969-09-12 | 1973-02-01 | Procedimiento para la preparacion de eteres heterociclicos. |
ES411188A Expired ES411188A1 (es) | 1969-09-12 | 1973-02-01 | Procedimiento para la preparacion de eteres heterociclicos. |
ES411186A Expired ES411186A1 (es) | 1969-09-12 | 1973-02-01 | Procedimiento para la preparacion de eteres heterociclicos. |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES383564A Expired ES383564A1 (es) | 1969-09-12 | 1970-09-11 | Procedimiento para la preparacion de eteres heterociclicos. |
ES411189A Expired ES411189A1 (es) | 1969-09-12 | 1973-02-01 | Procedimiento para la preparacion de eteres heterociclicos. |
ES411187A Expired ES411187A1 (es) | 1969-09-12 | 1973-02-01 | Procedimiento para la preparacion de eteres heterociclicos. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES411186A Expired ES411186A1 (es) | 1969-09-12 | 1973-02-01 | Procedimiento para la preparacion de eteres heterociclicos. |
Country Status (15)
Country | Link |
---|---|
US (1) | US3787411A (es) |
JP (1) | JPS4821949B1 (es) |
AT (4) | AT308127B (es) |
AU (1) | AU1977770A (es) |
BE (1) | BE756127A (es) |
BR (1) | BR6915366D0 (es) |
CA (1) | CA925508A (es) |
DE (1) | DE1946172A1 (es) |
ES (5) | ES383564A1 (es) |
FR (1) | FR2070687B1 (es) |
GB (1) | GB1320395A (es) |
IE (1) | IE34511B1 (es) |
IL (1) | IL35297A0 (es) |
NL (1) | NL7013189A (es) |
ZA (1) | ZA706140B (es) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3954763A (en) * | 1972-04-10 | 1976-05-04 | Synthelabo | N-Metatrifluoromethylthiophenyl-piperazine |
US4136185A (en) * | 1972-12-23 | 1979-01-23 | Boehringer Ingelheim Gmbh | N-Aryl-N'-(phenyl-or phenoxy-alkyl)-piperazines and salts thereof |
DE2337461A1 (de) * | 1973-07-24 | 1975-02-06 | Boehringer Mannheim Gmbh | Neue indolderivate und verfahren zu deren herstellung |
JPS572322Y2 (es) * | 1974-12-27 | 1982-01-14 | ||
JPS5260453U (es) * | 1975-10-28 | 1977-05-02 | ||
US4096331A (en) * | 1976-12-28 | 1978-06-20 | A. H. Robins Company, Incorporated | 1-Substituted-3-aminoethoxypyrrolidines |
US4104387A (en) * | 1977-05-23 | 1978-08-01 | E. R. Squibb & Sons, Inc. | 3-(Arylcycloiminoalkyl)benzisothiazole 1,1-dioxides |
JPS571800Y2 (es) * | 1977-05-31 | 1982-01-12 | ||
DE3005287A1 (de) * | 1980-02-13 | 1981-08-20 | Basf Ag, 6700 Ludwigshafen | Phenylpiperazinderivate von 1,3,4-oxadiazolylphenolen, ihre herstellung und diese enthaltende therapeutische mittel |
EP0107293A3 (en) * | 1982-09-04 | 1984-06-06 | Pfizer Limited | Dihydropyridines |
US4894453A (en) * | 1986-06-30 | 1990-01-16 | Toyo Jozo Kabushiki Kaisha | 2-substituted alkoxy-3-substituted-pyrazines |
FR2658514B1 (fr) * | 1990-02-19 | 1992-06-19 | Irceba | Nouveaux derives du methyl-4 thiazole, leurs procedes de preparation et les compositions pharmaceutiques en contenant. |
EP0555478A4 (en) * | 1990-08-31 | 1993-11-18 | Nippon Shinyaku Company, Limited | Pyrimidine derivative and medicine |
WO1993012792A1 (en) * | 1991-12-20 | 1993-07-08 | Asahi Kasei Kogyo Kabushiki Kaisha | Remedy for diseases related to serotonergic neuron system |
DE4425143A1 (de) * | 1994-07-15 | 1996-01-18 | Basf Ag | Substituierte Pyrimidinverbindungen und deren Verwendung |
CN1118454C (zh) * | 1994-09-09 | 2003-08-20 | 日本新药株式会社 | 杂环衍生物和医药 |
DE19728996A1 (de) | 1997-07-07 | 1999-01-14 | Basf Ag | Triazolverbindungen und deren Verwendung |
US9951088B2 (en) * | 2012-05-09 | 2018-04-24 | Sunovion Pharmaceuticals Inc. | D2 receptor modulators and methods of use thereof in the treatment of diseases and disorders |
CN107793362B (zh) * | 2016-08-30 | 2022-04-22 | 江苏恩华药业股份有限公司 | 一种苯基哒嗪酮类衍生物的合成及其应用 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE612485A (es) * | 1961-01-20 |
-
0
- BE BE756127D patent/BE756127A/xx unknown
-
1969
- 1969-09-12 DE DE19691946172 patent/DE1946172A1/de active Pending
- 1969-12-19 BR BR215366/69A patent/BR6915366D0/pt unknown
-
1970
- 1970-09-07 NL NL7013189A patent/NL7013189A/xx unknown
- 1970-09-08 IE IE1161/70A patent/IE34511B1/xx unknown
- 1970-09-08 US US00070486A patent/US3787411A/en not_active Expired - Lifetime
- 1970-09-09 ZA ZA706140A patent/ZA706140B/xx unknown
- 1970-09-10 AU AU19777/70A patent/AU1977770A/en not_active Expired
- 1970-09-10 CA CA092749A patent/CA925508A/en not_active Expired
- 1970-09-11 AT AT486272A patent/AT308127B/de not_active IP Right Cessation
- 1970-09-11 FR FR707033021A patent/FR2070687B1/fr not_active Expired
- 1970-09-11 AT AT486372A patent/AT309445B/de not_active IP Right Cessation
- 1970-09-11 AT AT827970A patent/AT305284B/de active
- 1970-09-11 ES ES383564A patent/ES383564A1/es not_active Expired
- 1970-09-11 AT AT486172A patent/AT308126B/de not_active IP Right Cessation
- 1970-09-12 JP JP45079911A patent/JPS4821949B1/ja active Pending
- 1970-09-14 GB GB4375470A patent/GB1320395A/en not_active Expired
- 1970-09-16 IL IL35297A patent/IL35297A0/xx unknown
-
1973
- 1973-02-01 ES ES411189A patent/ES411189A1/es not_active Expired
- 1973-02-01 ES ES411187A patent/ES411187A1/es not_active Expired
- 1973-02-01 ES ES411188A patent/ES411188A1/es not_active Expired
- 1973-02-01 ES ES411186A patent/ES411186A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES411186A1 (es) | 1975-12-01 |
DE1946172A1 (de) | 1971-03-18 |
ES411189A1 (es) | 1975-12-01 |
ZA706140B (en) | 1971-12-29 |
AT305284B (de) | 1973-02-26 |
US3787411A (en) | 1974-01-22 |
SU404251A3 (es) | 1973-10-26 |
FR2070687B1 (es) | 1973-08-10 |
AT309445B (de) | 1973-08-27 |
AU1977770A (en) | 1972-03-16 |
BE756127A (fr) | 1971-03-15 |
CA925508A (en) | 1973-05-01 |
ES383564A1 (es) | 1973-06-01 |
IL35297A0 (en) | 1970-11-30 |
NL7013189A (es) | 1971-03-16 |
IE34511L (en) | 1971-03-12 |
JPS4821949B1 (es) | 1973-07-02 |
IE34511B1 (en) | 1975-05-28 |
GB1320395A (en) | 1973-06-13 |
SU404252A3 (es) | 1973-10-26 |
AT308127B (de) | 1973-06-25 |
AT308126B (de) | 1973-06-25 |
BR6915366D0 (pt) | 1973-01-25 |
ES411187A1 (es) | 1975-12-01 |
FR2070687A1 (es) | 1971-09-17 |
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