ES408778A1 - Derivatives of double-stranded rna - Google Patents

Derivatives of double-stranded rna

Info

Publication number
ES408778A1
ES408778A1 ES408778A ES408778A ES408778A1 ES 408778 A1 ES408778 A1 ES 408778A1 ES 408778 A ES408778 A ES 408778A ES 408778 A ES408778 A ES 408778A ES 408778 A1 ES408778 A1 ES 408778A1
Authority
ES
Spain
Prior art keywords
double
stranded rna
rna
derivatives
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES408778A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES408778A1 publication Critical patent/ES408778A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A method for the preparation of a derivative of a double helix RNA, said derivative having interferon-inducing activity, the method of which is to react in solution a double helix RNA of natural origin and formaldehyde, carrying out the reaction at a temperature not higher substantially at the Tm of the double-stranded RNA in the particular solvent employed and for a period of time such that at least some of the hydrogen bonds between the complementary base pairs of the double-stranded RNA are conserved. (Machine-translation by Google Translate, not legally binding)
ES408778A 1971-11-20 1972-11-18 Derivatives of double-stranded rna Expired ES408778A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5402171A GB1411748A (en) 1971-11-20 1971-11-20 Derivatives of double-stranded rna

Publications (1)

Publication Number Publication Date
ES408778A1 true ES408778A1 (en) 1975-12-01

Family

ID=10469702

Family Applications (1)

Application Number Title Priority Date Filing Date
ES408778A Expired ES408778A1 (en) 1971-11-20 1972-11-18 Derivatives of double-stranded rna

Country Status (10)

Country Link
JP (1) JPS4862878A (en)
AU (1) AU474927B2 (en)
BE (1) BE791654A (en)
CH (1) CH571016A5 (en)
DE (1) DE2256781A1 (en)
DK (1) DK129793B (en)
ES (1) ES408778A1 (en)
FR (1) FR2160424A1 (en)
GB (1) GB1411748A (en)
NL (1) NL7215648A (en)

Also Published As

Publication number Publication date
GB1411748A (en) 1975-10-29
CH571016A5 (en) 1975-12-31
AU474927B2 (en) 1976-08-05
NL7215648A (en) 1973-05-22
DK129793B (en) 1974-11-18
AU4906772A (en) 1974-05-23
BE791654A (en) 1973-05-21
DE2256781A1 (en) 1973-05-24
DK129793C (en) 1975-04-28
FR2160424A1 (en) 1973-06-29
JPS4862878A (en) 1973-09-01

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