ES407633A1 - N-1-phenyl-n-5-pyrrolidylmethyl biguanides and their preparation - Google Patents

N-1-phenyl-n-5-pyrrolidylmethyl biguanides and their preparation

Info

Publication number
ES407633A1
ES407633A1 ES407633A ES407633A ES407633A1 ES 407633 A1 ES407633 A1 ES 407633A1 ES 407633 A ES407633 A ES 407633A ES 407633 A ES407633 A ES 407633A ES 407633 A1 ES407633 A1 ES 407633A1
Authority
ES
Spain
Prior art keywords
pyrrolidylmethyl
biguanides
phenyl
preparation
lower alcohol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES407633A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Original Assignee
Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe dEtudes Scientifiques et Industrielles de lIle de France SA filed Critical Societe dEtudes Scientifiques et Industrielles de lIle de France SA
Publication of ES407633A1 publication Critical patent/ES407633A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
    • C07C281/18—Compounds containing any of the groups, e.g. aminoguanidine the other nitrogen atom being further doubly-bound to a carbon atom, e.g. guanylhydrazones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/28—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to cyano groups, e.g. cyanoguanidines, dicyandiamides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for preparing new biguanide derivatives characterized by their formula: **(See formula)** wherein: A represents a halogen such as F, Cl, Br, I, a lower alcohol radical, or a lower alkoxy radical; and R represents a lower alcohol or hydroxy-lower alcohol radical, characterized in that the diazo compound of a para-substituted derivative of aniline is reacted with dicyandiamide, and in that the obtained compound is treated by means of a suitable N-alcohol- or hydroxy-alcoholylaminomethylpyrrolidine. (Machine-translation by Google Translate, not legally binding)
ES407633A 1971-10-18 1972-09-14 N-1-phenyl-n-5-pyrrolidylmethyl biguanides and their preparation Expired ES407633A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7137412A FR2156427B1 (en) 1971-10-18 1971-10-18

Publications (1)

Publication Number Publication Date
ES407633A1 true ES407633A1 (en) 1975-11-01

Family

ID=9084549

Family Applications (1)

Application Number Title Priority Date Filing Date
ES407633A Expired ES407633A1 (en) 1971-10-18 1972-09-14 N-1-phenyl-n-5-pyrrolidylmethyl biguanides and their preparation

Country Status (5)

Country Link
BE (1) BE790130A (en)
CH (1) CH544088A (en)
ES (1) ES407633A1 (en)
FR (1) FR2156427B1 (en)
GB (1) GB1368525A (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR6786M (en) * 1967-08-10 1969-03-17

Also Published As

Publication number Publication date
CH544088A (en) 1973-11-15
FR2156427A1 (en) 1973-06-01
DE2250856B2 (en) 1976-01-15
BE790130A (en) 1973-04-16
DE2250856A1 (en) 1973-04-26
FR2156427B1 (en) 1974-10-18
GB1368525A (en) 1974-09-25

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