ES396717A1 - Preparation of n-2-diethylamino-ethyl-2 1 methoxy -4-amino- 5-chlorobenzamide - Google Patents

Preparation of n-2-diethylamino-ethyl-2 1 methoxy -4-amino- 5-chlorobenzamide

Info

Publication number
ES396717A1
ES396717A1 ES396717A ES396717A ES396717A1 ES 396717 A1 ES396717 A1 ES 396717A1 ES 396717 A ES396717 A ES 396717A ES 396717 A ES396717 A ES 396717A ES 396717 A1 ES396717 A1 ES 396717A1
Authority
ES
Spain
Prior art keywords
amino
chlorobenzamide
methoxy
preparation
diethylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES396717A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fratmann SA
Original Assignee
Fratmann SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fratmann SA filed Critical Fratmann SA
Publication of ES396717A1 publication Critical patent/ES396717A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/475—Quinolines; Isoquinolines having an indole ring, e.g. yohimbine, reserpine, strychnine, vinblastine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedure for the preparation of N- (diethylaminoethyl) -2-methoxy-4-amino-5-chlorobenzamide by chlorination of an N-substituted and O-alkylated p-aminosalicylic acid ester and by its subsequent transformation by means of diethylaminoethylamine, characterized because after esterification and O-alkylation of p-aminosalicylic acid, the amino group in position 4 is replaced, before chlorination, by a radical of paratoluene sulfamido acid, which is removed again after transformation by means of diethylaminoethylamine. (Machine-translation by Google Translate, not legally binding)
ES396717A 1971-08-04 1971-11-05 Preparation of n-2-diethylamino-ethyl-2 1 methoxy -4-amino- 5-chlorobenzamide Expired ES396717A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1144371 1971-08-04

Publications (1)

Publication Number Publication Date
ES396717A1 true ES396717A1 (en) 1974-05-16

Family

ID=4373540

Family Applications (1)

Application Number Title Priority Date Filing Date
ES396717A Expired ES396717A1 (en) 1971-08-04 1971-11-05 Preparation of n-2-diethylamino-ethyl-2 1 methoxy -4-amino- 5-chlorobenzamide

Country Status (27)

Country Link
JP (1) JPS557422B1 (en)
BE (1) BE774300A (en)
BG (1) BG19590A3 (en)
CA (1) CA975798A (en)
CH (1) CH547262A (en)
CS (1) CS171164B2 (en)
DE (1) DE2152369A1 (en)
DK (1) DK129036B (en)
ES (1) ES396717A1 (en)
FI (1) FI53968C (en)
FR (1) FR2111373A5 (en)
GB (1) GB1328580A (en)
HU (1) HU163868B (en)
IE (1) IE35820B1 (en)
IL (1) IL38097A0 (en)
IT (1) IT1050359B (en)
LU (1) LU64249A1 (en)
MC (1) MC895A1 (en)
NL (1) NL7114903A (en)
NO (1) NO133890C (en)
OA (1) OA03927A (en)
PL (1) PL84572B1 (en)
RO (1) RO62478A (en)
SE (1) SE366298B (en)
YU (1) YU34787B (en)
ZA (1) ZA717542B (en)
ZM (1) ZM17171A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5759075U (en) * 1980-09-20 1982-04-07
JPS5882560U (en) * 1981-11-30 1983-06-04 いすゞ自動車株式会社 gasket

Also Published As

Publication number Publication date
IE35820B1 (en) 1976-05-26
NL7114903A (en) 1973-02-06
GB1328580A (en) 1973-08-30
OA03927A (en) 1975-08-14
IT1050359B (en) 1981-03-10
RO62478A (en) 1978-03-15
YU282271A (en) 1979-09-10
ZM17171A1 (en) 1972-07-21
IL38097A0 (en) 1972-01-27
FI53968C (en) 1978-09-11
HU163868B (en) 1973-11-28
FR2111373A5 (en) 1972-06-02
CA975798A (en) 1975-10-07
JPS557422B1 (en) 1980-02-25
PL84572B1 (en) 1976-04-30
SE366298B (en) 1974-04-22
CH547262A (en) 1974-03-29
LU64249A1 (en) 1972-06-02
DE2152369A1 (en) 1973-02-15
FI53968B (en) 1978-05-31
MC895A1 (en) 1972-06-22
BG19590A3 (en) 1975-06-25
CS171164B2 (en) 1976-10-29
DK129036B (en) 1974-08-12
NO133890C (en) 1976-07-14
NO133890B (en) 1976-04-05
BE774300A (en) 1972-04-24
YU34787B (en) 1980-03-15
IE35820L (en) 1973-02-04
ZA717542B (en) 1972-08-30
AU3572071A (en) 1973-05-24

Similar Documents

Publication Publication Date Title
IL47820A0 (en) New derivatives of 3-quinoline carboxylic acid,process for preparing them and pharmaceutical compositions
ES398963A1 (en) Cephalosporin process and product
ES396717A1 (en) Preparation of n-2-diethylamino-ethyl-2 1 methoxy -4-amino- 5-chlorobenzamide
ES454085A1 (en) Procedure for the preparation of N- (r-tetrahydrofurfuril) -noroximorphone and N- (s-tetrahydrofurfuril) -noroximorphone new. (Machine-translation by Google Translate, not legally binding)
FR2283184A1 (en) HYDRODUCABLE COMPOSITION OF HYDROXY (POLYALCOYLENE-CARBONYLOXY) ALCOYLENE-OXAZOLIDINE AND AN ISOCYANATE, AND PROCESS FOR ITS PREPARATION
IL37640A0 (en) Pharmaceutical and veterinary compositions containing an amino carboxylic acid derivative
IL46402A0 (en) New carboxylic acids,process for preparing them and pharmaceutical compositions
IL44912A (en) N-(4-quinolyl) anthranilic acid esters,process for preparing them and pharmaceutical compositions
ES426212A1 (en) Benzamide derivative
BE815202A (en) PROCESS FOR N-METHYLATION OF ALIPHATIC AMINES
ES413391A1 (en) Preparation of n-tertiary aminoalkyl-2-alkoxy benzamides and benzoic anhydride derivatives produced during it
HU171836B (en) Process for preparing derivatives of thiazole/5,4-f/quinoline-8-carboxylic acid
ES406424A1 (en) Procedure for obtaining a new derivative of the 3,4,5 trimetoxibenzoic acid and its salts. (Machine-translation by Google Translate, not legally binding)
CS181672B2 (en) Process for preparing derivatives of alfa-/aminophenyl/aliphatic carboxylic acids
ES372104A1 (en) Procedure for preparation of 2,4,5-substitute benzamides. (Machine-translation by Google Translate, not legally binding)
ES404059A1 (en) Hydroxytoluic acid derivatives processes for their preparation and pharmaceutical preparations containing them
ES406423A1 (en) Procedure for obtaining a new derivative of the 3,4,5 trimetoxibenzoic acid and its salts. (Machine-translation by Google Translate, not legally binding)
ES287545A1 (en) Procedure for the production of N- (2,3-dimethylene) antranilic acid and its salts (Machine-translation by Google Translate, not legally binding)
ES407880A1 (en) Procedure for obtaining a new derivative of the 3,4,5-trimetoxibenozico acid and its salts. (Machine-translation by Google Translate, not legally binding)
ES291737A1 (en) Procedure for -dimetilfenil) antranºlico (Machine-translation by Google Translate, not legally binding)
CS181677B2 (en) Process for preparing derivatives of alfa-/aminophenyl/aliphatic carboxylic acids
CA486153A (en) Method of preparing aminoesters of n-substituted pyrrolidine 2,5-dicarboxylic acids
ES293218A1 (en) Procedure for the manufacture of media of radiological constraste (Machine-translation by Google Translate, not legally binding)
ES320497A1 (en) Procedure for the obtaining of dexamethasone 21-pivalate. (Machine-translation by Google Translate, not legally binding)
AU1569870A (en) New process for the preparation of n-(diethylaminoethyl)-4-amino-5-chloro-2-methoxybenzamide