ES393800A1 - Penicillin 1-oxides - Google Patents

Penicillin 1-oxides

Info

Publication number
ES393800A1
ES393800A1 ES393800A ES393800A ES393800A1 ES 393800 A1 ES393800 A1 ES 393800A1 ES 393800 A ES393800 A ES 393800A ES 393800 A ES393800 A ES 393800A ES 393800 A1 ES393800 A1 ES 393800A1
Authority
ES
Spain
Prior art keywords
group
formula
penicillin
oxides
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES393800A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Laboratories Ltd
Original Assignee
Glaxo Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Laboratories Ltd filed Critical Glaxo Laboratories Ltd
Publication of ES393800A1 publication Critical patent/ES393800A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D499/00Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

A procedure for the preparation of penicillin-1-oxides of the general formula ** (See formula) ** where R1CO represents an acyl group having 1 to 21 carbon atoms, R2 is a hydroxyl group or an esterified carboxylamino group and X represents SO in the alpha or beta configuration, a procedure in which a 3-isocyanate-penam of the formula ** (See formula) ** Where R1CO is an acyl group and X is a sulfur atom or a sulfoxide group, it is reacted with an aqueous acid or an alcohol or phenol, followed, when X is a sulfur atom, by oxidation of X to a sulfoxide group . (Machine-translation by Google Translate, not legally binding)
ES393800A 1970-07-31 1971-07-30 Penicillin 1-oxides Expired ES393800A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3718970 1970-07-31
GB5228570A GB1368233A (en) 1970-07-31 1970-11-03 Penicillin 1-oxides

Publications (1)

Publication Number Publication Date
ES393800A1 true ES393800A1 (en) 1974-07-16

Family

ID=26263366

Family Applications (1)

Application Number Title Priority Date Filing Date
ES393800A Expired ES393800A1 (en) 1970-07-31 1971-07-30 Penicillin 1-oxides

Country Status (10)

Country Link
JP (1) JPS554113B1 (en)
AT (2) AT324566B (en)
AU (1) AU467354B2 (en)
BE (1) BE770727A (en)
CH (3) CH592097A5 (en)
DE (2) DE2166022A1 (en)
ES (1) ES393800A1 (en)
FR (1) FR2104819B1 (en)
GB (1) GB1368233A (en)
NL (1) NL7110612A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4036846A (en) * 1976-04-26 1977-07-19 Pfizer Inc. 3-Hydroxy and 3-acetoxy-6-triphenyl-methylaminopenams

Also Published As

Publication number Publication date
AU3184371A (en) 1973-02-01
BE770727A (en) 1972-01-31
AT324566B (en) 1975-09-10
ATA281473A (en) 1975-07-15
JPS554113B1 (en) 1980-01-29
FR2104819B1 (en) 1975-08-01
GB1368233A (en) 1974-09-25
DE2138323A1 (en) 1972-02-10
FR2104819A1 (en) 1972-04-21
AU467354B2 (en) 1975-11-27
AT329073B (en) 1976-04-26
CH592097A5 (en) 1977-10-14
DE2166022A1 (en) 1972-09-28
CH591504A5 (en) 1977-09-30
CH594679A5 (en) 1978-01-13
NL7110612A (en) 1972-02-02

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