ES386599A1 - Derivatives of cephalosporanic acid - Google Patents

Derivatives of cephalosporanic acid

Info

Publication number
ES386599A1
ES386599A1 ES386599A ES386599A ES386599A1 ES 386599 A1 ES386599 A1 ES 386599A1 ES 386599 A ES386599 A ES 386599A ES 386599 A ES386599 A ES 386599A ES 386599 A1 ES386599 A1 ES 386599A1
Authority
ES
Spain
Prior art keywords
group
cephalosporanic acid
derivatives
hydrogen
phosgene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES386599A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM Delft BV
Original Assignee
Koninklijke Nederlandsche Gist en Spiritusfabriek BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninklijke Nederlandsche Gist en Spiritusfabriek BV filed Critical Koninklijke Nederlandsche Gist en Spiritusfabriek BV
Publication of ES386599A1 publication Critical patent/ES386599A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Procedure for obtaining 7-isocyanate-cephalosporic acid derivatives of general formulas: **(See formula)** where E is an easily separable ester group and R is hydrogen, a protected hydroxy group or an acyloxy group, characterized in that it comprises reacting phosgene with a cephalosporanic acid derivative chosen from the formulas: **(See formula)** where W is hydrogen or an easily separable group that is capable of reacting with phosgene, such as a silyl group. (Machine-translation by Google Translate, not legally binding)
ES386599A 1969-12-18 1970-12-18 Derivatives of cephalosporanic acid Expired ES386599A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB6184269 1969-12-18

Publications (1)

Publication Number Publication Date
ES386599A1 true ES386599A1 (en) 1973-11-16

Family

ID=10487533

Family Applications (1)

Application Number Title Priority Date Filing Date
ES386599A Expired ES386599A1 (en) 1969-12-18 1970-12-18 Derivatives of cephalosporanic acid

Country Status (10)

Country Link
CA (1) CA985670A (en)
CS (1) CS165353B2 (en)
DE (1) DE2062296C3 (en)
ES (1) ES386599A1 (en)
FR (1) FR2081379B1 (en)
GB (1) GB1341827A (en)
HU (1) HU162432B (en)
NL (1) NL148321B (en)
SU (1) SU416948A3 (en)
ZA (1) ZA708521B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1193478B (en) * 1979-06-14 1988-07-08 Ausonia Farma Srl PROCEDURE FOR THE PREPARATION OF 7- (L-AMINO-L-PHENYLACETAMIDE) -3-METHYL-3-CEFEM-4-PIVALOYLOXYSIMETYL CARBOXYLATE

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1432507A (en) * 1959-08-04 1966-03-25 Nat Res Dev Cephalosporin derivatives c.
US3173916A (en) * 1960-06-28 1965-03-16 Pfizer & Co C Derivatives of 7-aminocephalosporanic acid
SE311519B (en) * 1962-12-14 1969-06-16 Astra Ab
CH480365A (en) * 1965-01-18 1969-10-31 Ciba Geigy Process for the preparation of new derivatives of 7-aminocephalosporanic acid
NL155260B (en) * 1968-06-19 1977-12-15 Koninklijke Gist Spiritus PROCESS FOR THE PREPARATION OF DERIVATIVES OF 6-AMINOPENICILLAAN ACID.

Also Published As

Publication number Publication date
CA985670A (en) 1976-03-16
FR2081379B1 (en) 1974-08-30
DE2065462B2 (en) 1976-01-15
DE2065462A1 (en) 1973-10-18
DE2062296A1 (en) 1971-07-01
DE2062296B2 (en) 1974-08-15
NL7018387A (en) 1971-06-22
NL148321B (en) 1976-01-15
FR2081379A1 (en) 1971-12-03
GB1341827A (en) 1973-12-25
HU162432B (en) 1973-02-28
DE2062296C3 (en) 1975-04-17
CS165353B2 (en) 1975-12-22
SU416948A3 (en) 1974-02-25
ZA708521B (en) 1971-09-29

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