ES384063A1 - Procedure for the preparation of stable aqueous solutions of cardenolides sensitive to oxidation. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of stable aqueous solutions of cardenolides sensitive to oxidation. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES384063A1
ES384063A1 ES384063A ES384063A ES384063A1 ES 384063 A1 ES384063 A1 ES 384063A1 ES 384063 A ES384063 A ES 384063A ES 384063 A ES384063 A ES 384063A ES 384063 A1 ES384063 A1 ES 384063A1
Authority
ES
Spain
Prior art keywords
cardenolides
translation
oxidation
sensitive
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES384063A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Pharmaceutical Co filed Critical Warner Lambert Pharmaceutical Co
Publication of ES384063A1 publication Critical patent/ES384063A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Cosmetics (AREA)

Abstract

Process for the preparation of stable aqueous solutions of cardenolides sensitive to oxidation, especially of cimarine, characterized in that as stabilizing agent they comprise an oxyalkylated theophylline derivative, as well as a saturated aliphatic alcohol. (Machine-translation by Google Translate, not legally binding)
ES384063A 1969-09-30 1970-09-29 Procedure for the preparation of stable aqueous solutions of cardenolides sensitive to oxidation. (Machine-translation by Google Translate, not legally binding) Expired ES384063A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19691949340 DE1949340A1 (en) 1969-09-30 1969-09-30 Stable solutions of oxidation-sensitive cardenolides

Publications (1)

Publication Number Publication Date
ES384063A1 true ES384063A1 (en) 1973-05-01

Family

ID=5746944

Family Applications (1)

Application Number Title Priority Date Filing Date
ES384063A Expired ES384063A1 (en) 1969-09-30 1970-09-29 Procedure for the preparation of stable aqueous solutions of cardenolides sensitive to oxidation. (Machine-translation by Google Translate, not legally binding)

Country Status (6)

Country Link
JP (1) JPS4816172B1 (en)
AU (1) AU2050970A (en)
BE (1) BE756779A (en)
DE (1) DE1949340A1 (en)
ES (1) ES384063A1 (en)
FR (1) FR2070100A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE047692T2 (en) * 2008-08-01 2020-05-28 Chiesi Farm Spa Pharmaceutical compositions and methods for stabilizing the same
EP3734075A1 (en) 2019-04-29 2020-11-04 Samsung Electronics Co., Ltd. Scroll compressor

Also Published As

Publication number Publication date
DE1949340A1 (en) 1971-04-15
BE756779A (en) 1971-03-01
JPS4816172B1 (en) 1973-05-19
AU2050970A (en) 1972-04-13
FR2070100A1 (en) 1971-09-10

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