ES383319A1 - Process for preparing useful 17alpha-hydroxy-20-keto-and 17alpha, 21-dihydroxy-20-keto-pregnanes and derivatives and intermediates thereof
- Google Patents
Process for preparing useful 17alpha-hydroxy-20-keto-and 17alpha, 21-dihydroxy-20-keto-pregnanes and derivatives and intermediates thereof
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Roche Palo Alto LLC
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Roche Palo Alto LLC
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Publication of ES383319A1publicationCriticalpatent/ES383319A1/en
C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
C—CHEMISTRY; METALLURGY
C07—ORGANIC CHEMISTRY
C07J—STEROIDS
C07J75/00—Processes for the preparation of steroids in general
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Chemical & Material Sciences
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Organic Chemistry
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Health & Medical Sciences
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General Health & Medical Sciences
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Steroid Compounds
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Abstract
A process for the preparation of therapeutically important steroidal derivatives and new intermediate compounds useful in this process, characterized in that it comprises the steps of: a) .- treat a 17 α-ethinyl-17β-acyloxy-androstane with zinc in an ethylene glycol ether to give the corresponding 17-vinylidenandrostane and b) .- oxidize the resulting 17-vinylidene androstane. (Machine-translation by Google Translate, not legally binding)
ES383319A1969-09-021970-09-02Process for preparing useful 17alpha-hydroxy-20-keto-and 17alpha, 21-dihydroxy-20-keto-pregnanes and derivatives and intermediates thereof
ExpiredES383319A1
(en)
A procedure for the preparation of the compound 1,2-alfametilen-6,7-alpha-difluormethylen-20-espirox-4-en-3-ona. (Machine-translation by Google Translate, not legally binding)
A procedure for preparation of 3,16 beta-dihydroxy 16 alphaetinyl 19-nor 1,3,5 (10) -androstatrene. (Machine-translation by Google Translate, not legally binding)
A procedure for the preparation of a 1,2 alpha-methylen -6,7 alpha-dialometilen-20-espirox-4-eno 3 oxygenate. (Machine-translation by Google Translate, not legally binding)
A procedure for the preparation of 3; 17-dioles of the ciclopentanopolihidrofenantreno series (Machine-translation by Google Translate, not legally binding)
A procedure for the preparation of 3-oxo 17-beta-metoxy 17-alpha-methyl estra-4.9, ii-triene. (Machine-translation by Google Translate, not legally binding)