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Evonik Operations GmbH
Original Assignee
Degussa GmbH
Deutsche Gold und Silber Scheideanstalt
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Publication date
Application filed by Degussa GmbH, Deutsche Gold und Silber ScheideanstaltfiledCriticalDegussa GmbH
Priority to ES382498ApriorityCriticalpatent/ES382498A3/en
Publication of ES382498A3publicationCriticalpatent/ES382498A3/en
Low-Molecular Organic Synthesis Reactions Using Catalysts
(AREA)
Abstract
Procedure for the preparation of penicillamine or its hydrochloride by reaction of a branched aldehyde in an alpha carbon atom with ammonia and sulfur to obtain a thiazoline- Δ 3 and by a subsequent reaction of this with hydrocyanic acid to obtain thiazolidin-4- carbonitrile, characterized in that 1) the isobutyraldehyde is reacted with a sulfur-containing compound, or, preferably, with elemental sulfur and with NH4NO3.2NH3 or, preferably, liquid ammonia, optionally in the presence of a secondary and tertiary amine with azeotropic elimination of the reaction water to obtain 2-isopropyl-5.5-dimethyl-thiazoline- Δ 3. (Machine-translation by Google Translate, not legally binding)
ES382498A1970-08-061970-08-06Procedure for preparing penicilamine. (Machine-translation by Google Translate, not legally binding)
ExpiredES382498A3
(en)
A procedure for the preparation of l-alpha-hydrazino-beta-phenylpropionic acid compounds. (Machine-translation by Google Translate, not legally binding)