ES381019A1 - A method for preparing a salt of cation N-m-metoxybencil n, N-dimethyl-N-2-hydroxylyamamide. (Machine-translation by Google Translate, not legally binding) - Google Patents

A method for preparing a salt of cation N-m-metoxybencil n, N-dimethyl-N-2-hydroxylyamamide. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES381019A1
ES381019A1 ES381019A ES381019A ES381019A1 ES 381019 A1 ES381019 A1 ES 381019A1 ES 381019 A ES381019 A ES 381019A ES 381019 A ES381019 A ES 381019A ES 381019 A1 ES381019 A1 ES 381019A1
Authority
ES
Spain
Prior art keywords
group
formula
cation
translation
dimethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES381019A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of ES381019A1 publication Critical patent/ES381019A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)

Abstract

A method of preparing a salt of the cation N-m-methoxybenzyl-N, N-dimethyl-N-2-hydroxyethylammonium in which (a) a tertiary amine of formula (II) RN (CH3) 2 Where R is the 2-hydroxyethyl group, it is reacted with a compound of the formula (III) **(See formula)** where X is the methoxy group, and Z is a nucleophilic group; (b) a tertiary amine of formula (IV) **(See formula)** where X is the methoxy group, is reacted with a compound KZ, where R is the 2-hydroxyethyl group and Z is a nucleophilic group; (c) a tertiary amine of formula (V) **(See formula)** where X is the methoxy group and R is the 2-hydroxyethyl group, it is reacted with a compound CH3Z, where Z is a nucleophilic group; or (d) a secondary amine of formula (VI) **(See formula)** where X is the methoxy group and R is the 2-hydroxyethyl group, it is reacted with two equivalents of a methylating agent, CH3Z, where Z is a nucleophilic group. (Machine-translation by Google Translate, not legally binding)
ES381019A 1969-06-23 1970-06-22 A method for preparing a salt of cation N-m-metoxybencil n, N-dimethyl-N-2-hydroxylyamamide. (Machine-translation by Google Translate, not legally binding) Expired ES381019A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB3168669 1969-06-23
GB5923069 1969-12-04

Publications (1)

Publication Number Publication Date
ES381019A1 true ES381019A1 (en) 1972-10-16

Family

ID=26261039

Family Applications (2)

Application Number Title Priority Date Filing Date
ES381019A Expired ES381019A1 (en) 1969-06-23 1970-06-22 A method for preparing a salt of cation N-m-metoxybencil n, N-dimethyl-N-2-hydroxylyamamide. (Machine-translation by Google Translate, not legally binding)
ES411208A Expired ES411208A1 (en) 1969-06-23 1973-02-02 Cardiac fibrillation treated with methoxy - benzyl-dimethyl-hydroxyethyl ammonium

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES411208A Expired ES411208A1 (en) 1969-06-23 1973-02-02 Cardiac fibrillation treated with methoxy - benzyl-dimethyl-hydroxyethyl ammonium

Country Status (12)

Country Link
JP (2) JPS5312502B1 (en)
BE (1) BE752415A (en)
CA (1) CA979016A (en)
CH (1) CH540226A (en)
DE (1) DE2030692C3 (en)
DK (1) DK145155C (en)
ES (2) ES381019A1 (en)
FI (1) FI54598C (en)
FR (1) FR2053006A1 (en)
IL (1) IL34765A (en)
NL (1) NL162063C (en)
SE (1) SE397342B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4765826A (en) * 1986-05-19 1988-08-23 The Dow Chemical Company Substituted benzyltrialkylammonium salts and their use as plant growth enhancers

Also Published As

Publication number Publication date
IL34765A0 (en) 1970-08-19
DE2030692C3 (en) 1981-04-23
NL7009186A (en) 1970-12-28
JPS5540574B1 (en) 1980-10-18
FR2053006B1 (en) 1974-02-22
SE397342B (en) 1977-10-31
NL162063B (en) 1979-11-15
FI54598C (en) 1979-01-10
CA979016A (en) 1975-12-02
FR2053006A1 (en) 1971-04-16
DE2030692A1 (en) 1971-01-21
NL162063C (en) 1980-04-15
DK145155C (en) 1983-02-21
CH540226A (en) 1973-08-15
FI54598B (en) 1978-09-29
JPS5312502B1 (en) 1978-05-01
IL34765A (en) 1974-12-31
DK145155B (en) 1982-09-20
ES411208A1 (en) 1975-12-01
DE2030692B2 (en) 1980-07-10
BE752415A (en) 1970-12-23

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19840713