ES377925A1 - A procedure for the preparation of new piracinic compounds. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of new piracinic compounds. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES377925A1
ES377925A1 ES377925A ES377925A ES377925A1 ES 377925 A1 ES377925 A1 ES 377925A1 ES 377925 A ES377925 A ES 377925A ES 377925 A ES377925 A ES 377925A ES 377925 A1 ES377925 A1 ES 377925A1
Authority
ES
Spain
Prior art keywords
group
translation
compounds
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES377925A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Carlo Erba SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Carlo Erba SpA filed Critical Carlo Erba SpA
Publication of ES377925A1 publication Critical patent/ES377925A1/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

A procedure for the preparation of new pyrazinic compounds of the general formula (I): **(See formula)** wherein each of the groups R1, R2 and R3, which may be the same or different, is a hydrogen or halogen atom or an unsubstituted or substituted group of alkyl, alkoxy, hydroxyl, amino, acetylamino, phenyl or similar; R4 is an alkyl group (eg, ethyl, propyl, isopropyl, butyl, or isobutyl) or the respective alkenyl group (eg, allyl), or is preferably a cycloaliphatic hydrocarbon group, which, if desired, it can be substituted with an alkyl or alkoxy group (for example, cyclopentyl, cyclohexyl, methylcyclohexyl, etc.), characterized by reacting a compound of the general formula (II): **(See formula)** wherein R1, R2 and R3 have the same meaning as before, while R5 is an isocyanate or an amine group, or a urethane or urea radical, with an amine or an isocyanate containing the group R4 mentioned above. (Machine-translation by Google Translate, not legally binding)
ES377925A 1969-03-26 1970-03-25 A procedure for the preparation of new piracinic compounds. (Machine-translation by Google Translate, not legally binding) Expired ES377925A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1458169 1969-03-26

Publications (1)

Publication Number Publication Date
ES377925A1 true ES377925A1 (en) 1973-02-01

Family

ID=11145232

Family Applications (1)

Application Number Title Priority Date Filing Date
ES377925A Expired ES377925A1 (en) 1969-03-26 1970-03-25 A procedure for the preparation of new piracinic compounds. (Machine-translation by Google Translate, not legally binding)

Country Status (5)

Country Link
AT (1) AT305305B (en)
ES (1) ES377925A1 (en)
SE (1) SE359546B (en)
SU (1) SU514570A3 (en)
YU (1) YU33931B (en)

Also Published As

Publication number Publication date
SU514570A3 (en) 1976-05-15
AT305305B (en) 1973-02-26
SE359546B (en) 1973-09-03
YU33931B (en) 1978-09-08
YU63970A (en) 1978-02-28

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