ES374371A2 - A procedure for the preparation of new substitute indoles. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of new substitute indoles. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES374371A2 ES374371A2 ES374371A ES374371A ES374371A2 ES 374371 A2 ES374371 A2 ES 374371A2 ES 374371 A ES374371 A ES 374371A ES 374371 A ES374371 A ES 374371A ES 374371 A2 ES374371 A2 ES 374371A2
- Authority
- ES
- Spain
- Prior art keywords
- chloroindole
- alpha
- methyl
- translation
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
Abstract
Improvements introduced in the object of the main patent nº 371,374, requested on 10.9.69, by: "a process for the preparation of new substituted indoles", in particular racemic or optically active 1- (alpha-carboxyethyl) 2-methyl-3-para-chlorobenzoyl-6-chloroindole, and its esters or salts, characterized by reacting an alkaline agent with 2-methyl-3-parachlorobenzoyl-6-chloroindole to form an alkaline derivative of the latter, said alkaline derivative is condensed with a lower alkyl ester of the alpha-halogenated propionic acid, in which the term halogen represents an atom of chlorine, bromine or iodine, to obtain a lower alkyl ester of 1- (alpha-carboxyethyl) 2-methyl-3-parachlorobenzoyl 6-chloroindole, which is saponified to obtain 1- (alpha-carboxyethyl) 2-methyl 3-para-chlorobenzoyl 6-chloroindole which, if appropriate, is subjected to an esterification or salification agent, or is cleaved by means of an optically active base in its optical antipodes. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR75177431A FR8439M (en) | 1968-12-10 | 1968-12-10 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES374371A2 true ES374371A2 (en) | 1972-01-01 |
Family
ID=8658089
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES374371A Expired ES374371A2 (en) | 1968-12-10 | 1969-12-09 | A procedure for the preparation of new substitute indoles. (Machine-translation by Google Translate, not legally binding) |
Country Status (2)
Country | Link |
---|---|
ES (1) | ES374371A2 (en) |
FR (1) | FR8439M (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2554819B1 (en) * | 1983-11-10 | 1986-05-16 | Adir | NOVEL THIENO (2,3-B) PYRROLE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
FR2564467B1 (en) * | 1984-05-21 | 1987-08-21 | Adir | NOVEL THIENO (2,3-B) PYRROLE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
FR2565981B1 (en) * | 1984-06-15 | 1986-09-19 | Adir | NOVEL THIENO (2,3-B) PYRROLE DERIVATIVES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
-
1968
- 1968-12-10 FR FR75177431A patent/FR8439M/fr not_active Expired
-
1969
- 1969-12-09 ES ES374371A patent/ES374371A2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
FR8439M (en) | 1971-07-15 |
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