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Chugai Pharmaceutical Co Ltd
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Chugai Pharmaceutical Co Ltd
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Publication of ES373000A1publicationCriticalpatent/ES373000A1/en
Agricultural Chemicals And Associated Chemicals
(AREA)
Abstract
A process for the preparation of a uracil derivative of formula. ** (see formula) ** Where x represents a halogen atom or a hydrogen atom and r is selected from the group consisting of a hydrogen atom and an alkyl group, which process consists in reacting a monosubstituted urea of formula R-ch2-nhconh2 Wherein r is as defined above, with citric acid or a salt thereof, in the presence of a dehydration-condensation agent, to produce a 6-carboxymethyluracil derivative of formula ** (see formula) ** Where r is defined above; optionally halogenating the resulting product with a halogenating agent to obtain a 5-halo-6-carboxymethyl derivative of formula. ** (see formula) ** Where x is halogen and r is defined above; and thermally decarboxylating the resulting 5-hydro-5-halo-6-carboxymethyl derivative. (Machine-translation by Google Translate, not legally binding)
ES373000A1968-10-301969-10-29A procedure for the preparation of a uracila derivative. (Machine-translation by Google Translate, not legally binding)
ExpiredES373000A1
(en)
A procedure for the preparation of new derivatives of acid2,3-alquilen (lower) penam-3-carboxylic. (Machine-translation by Google Translate, not legally binding)
A procedure for the production of derivatives substituted of phenoxy-alpha-methylpropionic acid. (Machine-translation by Google Translate, not legally binding)