ES371557A1 - Vaccines - Google Patents

Vaccines

Info

Publication number
ES371557A1
ES371557A1 ES371557A ES371557A ES371557A1 ES 371557 A1 ES371557 A1 ES 371557A1 ES 371557 A ES371557 A ES 371557A ES 371557 A ES371557 A ES 371557A ES 371557 A1 ES371557 A1 ES 371557A1
Authority
ES
Spain
Prior art keywords
polynucleotide
antigen
copolymer
vaccines
hybrids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES371557A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES371557A1 publication Critical patent/ES371557A1/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/39Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55561CpG containing adjuvants; Oligonucleotide containing adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

A vaccine preparation comprises an antigen, an adjuvant and at least a sufficient amount of a polynucleotide to increase the potency of the antigen. The polynucleotide may be a complex of two homopolymers, an alternating copolymer, a copolymer of random distribution, or a naturally occurring double-stranded RNA, including their hybrids and chemically altered polynucleotides.
ES371557A 1968-09-19 1969-09-15 Vaccines Expired ES371557A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76100468A 1968-09-19 1968-09-19

Publications (1)

Publication Number Publication Date
ES371557A1 true ES371557A1 (en) 1972-03-16

Family

ID=25060824

Family Applications (1)

Application Number Title Priority Date Filing Date
ES371557A Expired ES371557A1 (en) 1968-09-19 1969-09-15 Vaccines

Country Status (18)

Country Link
JP (1) JPS502009B1 (en)
AT (1) AT296500B (en)
BE (1) BE739046A (en)
BR (1) BR6912481D0 (en)
CA (1) CA918072A (en)
CS (1) CS160110B2 (en)
DE (1) DE1946319A1 (en)
DK (1) DK128503B (en)
ES (1) ES371557A1 (en)
FI (1) FI46863C (en)
FR (1) FR2018431B1 (en)
GB (1) GB1234718A (en)
IE (1) IE33578B1 (en)
IL (1) IL32962A (en)
NL (1) NL167324C (en)
PL (1) PL80303B1 (en)
SE (1) SE364987B (en)
ZA (1) ZA695759B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8301996A (en) * 1983-06-06 1985-01-02 Duphar Int Res METHOD FOR PREPARING ADVISED LIVE VACCINES AND SO OBTAINED VACCINES OBTAINED.
EP0930893B1 (en) 1996-10-11 2005-04-13 The Regents of The University of California Immunostimulatory polynucleotide/immunomodulatory molecule conjugates

Also Published As

Publication number Publication date
BE739046A (en) 1970-03-18
CS160110B2 (en) 1975-02-28
DE1946319A1 (en) 1970-03-26
AT296500B (en) 1972-02-10
GB1234718A (en) 1971-06-09
SU441711A3 (en) 1974-08-30
NL6913336A (en) 1970-03-23
IL32962A (en) 1973-01-30
IE33578L (en) 1970-03-19
ZA695759B (en) 1971-03-31
FI46863B (en) 1973-04-02
FI46863C (en) 1973-07-10
NL167324C (en) 1981-12-16
FR2018431A1 (en) 1970-05-29
IE33578B1 (en) 1974-08-21
NL167324B (en) 1981-07-16
CA918072A (en) 1973-01-02
IL32962A0 (en) 1969-11-30
JPS502009B1 (en) 1975-01-23
BR6912481D0 (en) 1973-02-08
FR2018431B1 (en) 1973-06-08
PL80303B1 (en) 1975-08-30
SE364987B (en) 1974-03-11
DK128503B (en) 1974-05-13

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