ES370665A1 - Un metodo de preparacion de una 5-amino sustituido - 6 - halo - 1h - imidazo (4,5-b) pirazin-2-ona - Google Patents

Un metodo de preparacion de una 5-amino sustituido - 6 - halo - 1h - imidazo (4,5-b) pirazin-2-ona

Info

Publication number
ES370665A1
ES370665A1 ES370665A ES370665A ES370665A1 ES 370665 A1 ES370665 A1 ES 370665A1 ES 370665 A ES370665 A ES 370665A ES 370665 A ES370665 A ES 370665A ES 370665 A1 ES370665 A1 ES 370665A1
Authority
ES
Spain
Prior art keywords
general formula
diamino
alkyl
amino
bromide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES370665A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES370665A1 publication Critical patent/ES370665A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/20—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES370665A 1968-08-22 1969-08-20 Un metodo de preparacion de una 5-amino sustituido - 6 - halo - 1h - imidazo (4,5-b) pirazin-2-ona Expired ES370665A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US75471168A 1968-08-22 1968-08-22

Publications (1)

Publication Number Publication Date
ES370665A1 true ES370665A1 (es) 1971-10-16

Family

ID=25035981

Family Applications (1)

Application Number Title Priority Date Filing Date
ES370665A Expired ES370665A1 (es) 1968-08-22 1969-08-20 Un metodo de preparacion de una 5-amino sustituido - 6 - halo - 1h - imidazo (4,5-b) pirazin-2-ona

Country Status (6)

Country Link
US (1) US3541093A (enExample)
AT (1) AT292710B (enExample)
BR (1) BR6911596D0 (enExample)
ES (1) ES370665A1 (enExample)
GB (1) GB1230908A (enExample)
NL (1) NL6911326A (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4418062A (en) * 1981-08-24 1983-11-29 Merck & Co., Inc. Amino derivatives of chloro nitro amino pyrazines useful as adjuncts to radiation therapy
US4414215A (en) * 1981-08-24 1983-11-08 Merck & Co., Inc. N-Acyl derivatives of 6-alkylamino 5-chloro-3-nitropyrazinamines for radiation therapy
US4438266A (en) 1982-05-17 1984-03-20 Merck & Co., Inc. Triazolopyrazinamines useful as adjuncts to radiation therapy
EP0096125B1 (en) * 1982-06-09 1987-01-07 Merck & Co. Inc. Amino and amido derivatives of chloro nitro amino and alkylamino pyrazines useful as adjuncts to radiation therapy
US4709035A (en) * 1982-11-12 1987-11-24 Merck & Co., Inc. 2,6-disubstituted derivatives of 3-nitropyrazines useful as adjuncts to radiation therapy
US4609659A (en) * 1985-01-16 1986-09-02 Merck & Co., Inc. 2,6-disubstituted derivatives of 3-nitropyrazines useful as adjuncts to radiation therapy
US4882880A (en) * 1988-05-17 1989-11-28 Schaffner Manufacturing Company, Inc. Ganging of buffing wheels

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3461123A (en) * 1968-04-12 1969-08-12 Merck & Co Inc 1h-imidazo(4,5-b)pyrazin-2-ones and processes for their preparation

Also Published As

Publication number Publication date
GB1230908A (enExample) 1971-05-05
NL6911326A (enExample) 1970-02-24
BR6911596D0 (pt) 1973-02-13
US3541093A (en) 1970-11-17
AT292710B (de) 1971-09-10

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