ES363875A1 - Procedure for the obtaining of heterociclic compounds. (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for the obtaining of heterociclic compounds. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES363875A1 ES363875A1 ES363875A ES363875A ES363875A1 ES 363875 A1 ES363875 A1 ES 363875A1 ES 363875 A ES363875 A ES 363875A ES 363875 A ES363875 A ES 363875A ES 363875 A1 ES363875 A1 ES 363875A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- compound
- translation
- procedure
- obtaining
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/18—Eight-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Novel compounds (I) in which A is H, halo, alkyl, alkoxy, haloalkyl or cyano X is a methylene group or a heteroatom B is H or alkyl Y is -CH(CH 3 )-CH 2 -, -CH(CH 3 )-CO- or -CH 2 -CH(CH 3 )- R and R1 are H or alkyl or together with the nitrogen atom to which they are attached form a heterocyclic radical which may contain a further heteroatom and acid addition salts thereof are prepared by (a) when Y is reacting the N unsubstituted heterocycle with a compound wherein Hal is a halogen atom: (b) when Y is -CH(CH 3 )-CH 2 - or -CH 2 -CH(CH 3 )- reducinga compound (I) in which Y is -CH(CH 3 )- CO- or -CO-CH(CH 3 )- respectively or (c) when Y is -CH(CH 3 )-CH 2 - or -CH 2 - CH(CH 3 )- condensing an alkali metal derivative (VII) with a halo-propylamine to give a mixture of isomers (I) in which Y is -CH(CH 3 )-CH 2 - or -CH 2 -CH(CH 3 )- respectively, followed in (a), (b) or (c), where necessary, by salt formation. Pharmaceutical compositions comprise a compound (I) in association with a carrier or diluent for oral or parenteral application and are effective as anti-depressants, stimulants, anoexigenies, anti-histaminics, anti-spasmodics, sedatives and hypnotics.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB884168 | 1968-02-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES363875A1 true ES363875A1 (en) | 1971-01-01 |
Family
ID=9860259
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES363875A Expired ES363875A1 (en) | 1968-02-23 | 1969-02-20 | Procedure for the obtaining of heterociclic compounds. (Machine-translation by Google Translate, not legally binding) |
Country Status (7)
| Country | Link |
|---|---|
| BE (1) | BE728677A (en) |
| BR (1) | BR6906571D0 (en) |
| DE (1) | DE1909038A1 (en) |
| ES (1) | ES363875A1 (en) |
| FR (1) | FR2002463A1 (en) |
| GB (1) | GB1183442A (en) |
| NL (1) | NL6902595A (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS563348B2 (en) * | 1972-02-18 | 1981-01-24 | ||
| US4537885A (en) * | 1983-02-10 | 1985-08-27 | Ciba Geigy Corporation | Certain benzazocinone and benzazoninone derivatives |
| US4470988A (en) * | 1983-02-10 | 1984-09-11 | Ciba-Geigy Corporation | Benzazocinone and benzazoninone derivatives, and their pharmaceutical use |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1518650A (en) * | 1965-09-15 | 1968-03-29 | Ucb Sa | Process for preparing heterocyclic derivatives, in particular benzothiazacy clanones and benzothiazacyclanes |
-
1968
- 1968-02-23 GB GB1183442D patent/GB1183442A/en not_active Expired
-
1969
- 1969-02-19 NL NL6902595A patent/NL6902595A/xx unknown
- 1969-02-19 FR FR6904237A patent/FR2002463A1/en not_active Withdrawn
- 1969-02-20 ES ES363875A patent/ES363875A1/en not_active Expired
- 1969-02-20 BE BE728677D patent/BE728677A/xx unknown
- 1969-02-21 BR BR20657169A patent/BR6906571D0/en unknown
- 1969-02-22 DE DE19691909038 patent/DE1909038A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BE728677A (en) | 1969-08-20 |
| FR2002463A1 (en) | 1969-10-17 |
| NL6902595A (en) | 1969-08-26 |
| DE1909038A1 (en) | 1969-09-04 |
| GB1183442A (en) | 1970-03-04 |
| BR6906571D0 (en) | 1973-04-19 |
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