ES361320A1 - A procedure for the preparation of 3-hydroxy-alpha (aminoethyl) -bencil alcohol derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of 3-hydroxy-alpha (aminoethyl) -bencil alcohol derivatives. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES361320A1
ES361320A1 ES361320A ES361320A ES361320A1 ES 361320 A1 ES361320 A1 ES 361320A1 ES 361320 A ES361320 A ES 361320A ES 361320 A ES361320 A ES 361320A ES 361320 A1 ES361320 A1 ES 361320A1
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ES
Spain
Prior art keywords
formula
alkyl
phenyl
hydrogen
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES361320A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Priority to ES361320A priority Critical patent/ES361320A1/en
Publication of ES361320A1 publication Critical patent/ES361320A1/en
Expired legal-status Critical Current

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Abstract

A process for the preparation of 3-hydroxy-alpha- (aminoethyl) -benzyl alcohol derivatives of formula: **(See formula)** where R1 is hydrogen, alkyl, substituted alkyl, cycloalkyl, alkenyl, cycloalkenyl, alkoxy, phenyl, substituted phenyl, benzyl, substituted benzyl or a heterocyclic radical; R2 is hydrogen, alkyl, phenyl, or substituted phenyl and where R1 and R2 can be changed to form a saturated or unsaturated alicyclic or heterocyclic ring; R3 is hydrogen, alkyl or phenyl, X is hydrogen, halogen, alkoxy, alkyl or phenyl, and n is 0 or the integer 1; whose procedure consists of: (a) react a compound of formula: **(See formula)** where X is as defined above, with a lower alkanoic anhydride or a lower alkyl acid halide, to form a compound of the formula: (b) react the product of step (a) above, with R-X1, where R is the radical **(See formula)** where R1, R2, R3 and n are those defined above; and X1 is halogen, a sulfonic ester, or a quaternary ammonium derivative, to form a compound of the formula: **(See formula)** where R1, R2, R3 and n are those defined above, (c) deacylizing the compound produced in step (b) to form the desired product. (Machine-translation by Google Translate, not legally binding)
ES361320A 1968-12-11 1968-12-11 A procedure for the preparation of 3-hydroxy-alpha (aminoethyl) -bencil alcohol derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES361320A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES361320A ES361320A1 (en) 1968-12-11 1968-12-11 A procedure for the preparation of 3-hydroxy-alpha (aminoethyl) -bencil alcohol derivatives. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES361320A ES361320A1 (en) 1968-12-11 1968-12-11 A procedure for the preparation of 3-hydroxy-alpha (aminoethyl) -bencil alcohol derivatives. (Machine-translation by Google Translate, not legally binding)

Publications (1)

Publication Number Publication Date
ES361320A1 true ES361320A1 (en) 1970-11-16

Family

ID=8451273

Family Applications (1)

Application Number Title Priority Date Filing Date
ES361320A Expired ES361320A1 (en) 1968-12-11 1968-12-11 A procedure for the preparation of 3-hydroxy-alpha (aminoethyl) -bencil alcohol derivatives. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES361320A1 (en)

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