ES359536A1 - Antibacterial epoxypropylphosphonic acid and esters - as an antibiotic - Google Patents
Antibacterial epoxypropylphosphonic acid and esters - as an antibioticInfo
- Publication number
- ES359536A1 ES359536A1 ES359536A ES359536A ES359536A1 ES 359536 A1 ES359536 A1 ES 359536A1 ES 359536 A ES359536 A ES 359536A ES 359536 A ES359536 A ES 359536A ES 359536 A1 ES359536 A1 ES 359536A1
- Authority
- ES
- Spain
- Prior art keywords
- esters
- antibiotic
- antibacterial
- epoxypropylphosphonic acid
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002148 esters Chemical class 0.000 title abstract 2
- 239000002253 acid Substances 0.000 title 1
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 230000003115 biocidal effect Effects 0.000 title 1
- 241000193830 Bacillus <bacterium> Species 0.000 abstract 1
- 241000588722 Escherichia Species 0.000 abstract 1
- 206010034133 Pathogen resistance Diseases 0.000 abstract 1
- ABLZXFCXXLZCGV-UHFFFAOYSA-N Phosphorous acid Chemical compound OP(O)=O ABLZXFCXXLZCGV-UHFFFAOYSA-N 0.000 abstract 1
- 241000588769 Proteus <enterobacteria> Species 0.000 abstract 1
- 241000607142 Salmonella Species 0.000 abstract 1
- 241000191940 Staphylococcus Species 0.000 abstract 1
- 125000005741 alkyl alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3826—Acyclic unsaturated acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65502—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a three-membered ring
- C07F9/65505—Phosphonic acids containing oxirane groups; esters thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
(+-) (Trans-1,2-epoxypropyl)phosphonic acid and esters (I) and salts R = h or hydrocarbyl, e.g. lower alkyl/alkenyl/alkynyl, cycloalkyl, aralkyl, aryl, heteroaryl. - Active against Bacillus, Escherichia, Staphylococcus, Salmonella and Proteus spp. including antibiotic-resistant strains.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US72942168A | 1968-05-15 | 1968-05-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES359536A1 true ES359536A1 (en) | 1970-08-16 |
Family
ID=24930945
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES359536A Expired ES359536A1 (en) | 1968-05-15 | 1968-10-25 | Antibacterial epoxypropylphosphonic acid and esters - as an antibiotic |
Country Status (8)
Country | Link |
---|---|
BE (1) | BE723077A (en) |
DE (1) | DE1805685A1 (en) |
ES (1) | ES359536A1 (en) |
IL (1) | IL30916A0 (en) |
LU (1) | LU57185A1 (en) |
MT (1) | MTP585B (en) |
NL (1) | NL6814976A (en) |
ZM (1) | ZM13668A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2522081A1 (en) * | 1975-05-17 | 1976-11-25 | Boehringer Mannheim Gmbh | ANTIBIOTICALLY EFFECTIVE PREPARATION |
CN113522269B (en) * | 2021-08-20 | 2023-05-02 | 四川大学华西医院 | Based on Zn 2 V 2 O 7 Nanocrystalline biocatalysts and their use in the preparation of enzyme-like preparations and antibacterial agents |
CN117964661A (en) * | 2024-04-01 | 2024-05-03 | 深圳创元生物医药科技有限公司 | Preparation method of fosfomycin genotoxic impurity C |
-
1968
- 1968-10-18 NL NL6814976A patent/NL6814976A/xx unknown
- 1968-10-21 IL IL30916A patent/IL30916A0/en unknown
- 1968-10-25 ES ES359536A patent/ES359536A1/en not_active Expired
- 1968-10-28 DE DE19681805685 patent/DE1805685A1/en active Pending
- 1968-10-29 LU LU57185D patent/LU57185A1/xx unknown
- 1968-10-29 BE BE723077D patent/BE723077A/xx unknown
- 1968-10-30 ZM ZM136/68A patent/ZM13668A1/en unknown
- 1968-11-11 MT MT585A patent/MTP585B/en unknown
Also Published As
Publication number | Publication date |
---|---|
BE723077A (en) | 1969-04-29 |
MTP585B (en) | 1970-05-18 |
IL30916A0 (en) | 1968-12-26 |
NL6814976A (en) | 1969-11-18 |
DE1805685A1 (en) | 1970-05-27 |
ZM13668A1 (en) | 1970-06-18 |
LU57185A1 (en) | 1969-05-16 |
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