ES356116A1 - Procedimiento para la preparacion de 3-metil-19-nor-3,5-an-drostadien - 17 betaoles. - Google Patents
Procedimiento para la preparacion de 3-metil-19-nor-3,5-an-drostadien - 17 betaoles.Info
- Publication number
- ES356116A1 ES356116A1 ES356116A ES356116A ES356116A1 ES 356116 A1 ES356116 A1 ES 356116A1 ES 356116 A ES356116 A ES 356116A ES 356116 A ES356116 A ES 356116A ES 356116 A1 ES356116 A1 ES 356116A1
- Authority
- ES
- Spain
- Prior art keywords
- ethynyl
- methyl
- methylene
- androstadiene
- 17alpha
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HSFWRNGVRCDJHI-UHFFFAOYSA-N alpha-acetylene Natural products C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 abstract 2
- 125000002534 ethynyl group Chemical group [H]C#C* 0.000 abstract 2
- 238000006317 isomerization reaction Methods 0.000 abstract 2
- BZIJFYVCWHAZOR-HVTWWXFQSA-N (8S,9S,10R,13S,14S)-10,13-dimethyl-3-methylidene-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene Chemical class C=C1C=C2CC[C@@H]3[C@H](CC[C@@]4(CCC[C@H]43)C)[C@]2(CC1)C BZIJFYVCWHAZOR-HVTWWXFQSA-N 0.000 abstract 1
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 230000001833 anti-estrogenic effect Effects 0.000 abstract 1
- 230000003509 anti-fertility effect Effects 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001076 estrogenic effect Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- XYDYWTJEGDZLTH-UHFFFAOYSA-N methylenetriphenylphosphorane Chemical group C=1C=CC=CC=1P(C=1C=CC=CC=1)(=C)C1=CC=CC=C1 XYDYWTJEGDZLTH-UHFFFAOYSA-N 0.000 abstract 1
- 229960001566 methyltestosterone Drugs 0.000 abstract 1
- 230000016087 ovulation Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DEM0074767 | 1967-07-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES356116A1 true ES356116A1 (es) | 1970-01-01 |
Family
ID=7315880
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES356116A Expired ES356116A1 (es) | 1967-07-15 | 1968-07-13 | Procedimiento para la preparacion de 3-metil-19-nor-3,5-an-drostadien - 17 betaoles. |
Country Status (10)
Country | Link |
---|---|
US (1) | US3705915A (en:Method) |
BE (1) | BE717954A (en:Method) |
CH (1) | CH501603A (en:Method) |
DK (1) | DK122277B (en:Method) |
ES (1) | ES356116A1 (en:Method) |
FR (1) | FR8068M (en:Method) |
GB (1) | GB1154120A (en:Method) |
IL (1) | IL30048A0 (en:Method) |
NL (1) | NL6807510A (en:Method) |
SE (1) | SE337218B (en:Method) |
-
1968
- 1968-05-20 GB GB23955/68A patent/GB1154120A/en not_active Expired
- 1968-05-22 IL IL30048A patent/IL30048A0/xx unknown
- 1968-05-22 CH CH762468A patent/CH501603A/de not_active IP Right Cessation
- 1968-05-28 NL NL6807510A patent/NL6807510A/xx unknown
- 1968-05-28 FR FR153143A patent/FR8068M/fr not_active Expired
- 1968-06-25 DK DK301768AA patent/DK122277B/da unknown
- 1968-07-11 BE BE717954D patent/BE717954A/xx unknown
- 1968-07-12 SE SE09622/68A patent/SE337218B/xx unknown
- 1968-07-13 ES ES356116A patent/ES356116A1/es not_active Expired
-
1970
- 1970-11-24 US US92175A patent/US3705915A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
IL30048A0 (en) | 1968-07-25 |
CH501603A (de) | 1971-01-15 |
GB1154120A (en) | 1969-06-04 |
FR8068M (en:Method) | 1970-07-15 |
BE717954A (en:Method) | 1969-01-13 |
NL6807510A (en:Method) | 1969-01-17 |
DK122277B (da) | 1972-02-14 |
US3705915A (en) | 1972-12-12 |
SE337218B (en:Method) | 1971-08-02 |
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