ES352696A1 - A procedure for the preparation of a compound of the group formed by 7-rent- (and 7-cicloalquil-lower rent) 4- (4-piridyl) -2,2,3-trialquil-5-chromanol. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the preparation of a compound of the group formed by 7-rent- (and 7-cicloalquil-lower rent) 4- (4-piridyl) -2,2,3-trialquil-5-chromanol. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES352696A1 ES352696A1 ES352696A ES352696A ES352696A1 ES 352696 A1 ES352696 A1 ES 352696A1 ES 352696 A ES352696 A ES 352696A ES 352696 A ES352696 A ES 352696A ES 352696 A1 ES352696 A1 ES 352696A1
- Authority
- ES
- Spain
- Prior art keywords
- rent
- compound
- chromanol
- alkyl
- translation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000000339 4-pyridyl group Chemical group N1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 150000004791 alkyl magnesium halides Chemical class 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical group II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A process for the preparation of a compound from the group consisting of 7-alkyl- (and 7-cyloalkyl-lower-alkyl-chyl) -4- (4-pyridyl) -2,2,3-trialkyl-5-chromanol and 2, 2-dialkyl-7-alkyl- (and 7-cycloalkyl-lower alkyl) -4- (4-pyridyl) -2H-chromen-5-ol, of formulas **(See formula)** where R1 is lower alkyl and R2 is a member of the group consisting of alkyl and cycloalkyl-lower alkyl, the process of which is to react a compound of formula **(See formula)** where R2 has the meaning given above, with a lower alkyl magnesium halide of formula R1MgX, where R1 has the meaning given above and X is bromine or iodine, at elevated temperature. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63080867A | 1967-04-14 | 1967-04-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES352696A1 true ES352696A1 (en) | 1969-07-16 |
Family
ID=24528640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES352696A Expired ES352696A1 (en) | 1967-04-14 | 1968-04-11 | A procedure for the preparation of a compound of the group formed by 7-rent- (and 7-cicloalquil-lower rent) 4- (4-piridyl) -2,2,3-trialquil-5-chromanol. (Machine-translation by Google Translate, not legally binding) |
Country Status (8)
| Country | Link |
|---|---|
| AT (1) | AT276395B (en) |
| CA (1) | CA931956A (en) |
| DK (2) | DK126856B (en) |
| ES (1) | ES352696A1 (en) |
| FI (1) | FI51101C (en) |
| IE (1) | IE32014B1 (en) |
| NO (2) | NO128711B (en) |
| SE (1) | SE343300B (en) |
-
1968
- 1968-04-08 CA CA017015A patent/CA931956A/en not_active Expired
- 1968-04-08 IE IE402/68A patent/IE32014B1/en unknown
- 1968-04-09 DK DK158468AA patent/DK126856B/en unknown
- 1968-04-09 NO NO01398/68A patent/NO128711B/no unknown
- 1968-04-10 SE SE4903/68A patent/SE343300B/en unknown
- 1968-04-11 FI FI681030A patent/FI51101C/en active
- 1968-04-11 ES ES352696A patent/ES352696A1/en not_active Expired
- 1968-04-12 AT AT363968A patent/AT276395B/en active
-
1969
- 1969-02-27 DK DK108769AA patent/DK127121B/en unknown
-
1971
- 1971-02-05 NO NO71434A patent/NO132431C/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA931956A (en) | 1973-08-14 |
| NO132431C (en) | 1975-11-12 |
| AT276395B (en) | 1969-11-25 |
| FI51101C (en) | 1976-10-11 |
| SE343300B (en) | 1972-03-06 |
| IE32014L (en) | 1968-10-14 |
| FI51101B (en) | 1976-06-30 |
| DK127121B (en) | 1973-09-24 |
| NO128711B (en) | 1974-01-02 |
| NO132431B (en) | 1975-08-04 |
| IE32014B1 (en) | 1973-03-21 |
| DK126856B (en) | 1973-08-27 |
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