ES350523A1 - Procedimiento para la fabricacion de ariloxi-isoalquil-del-ta2-imidazolinas y sus sales de acidos de adicion. - Google Patents
Procedimiento para la fabricacion de ariloxi-isoalquil-del-ta2-imidazolinas y sus sales de acidos de adicion.Info
- Publication number
- ES350523A1 ES350523A1 ES350523A ES350523A ES350523A1 ES 350523 A1 ES350523 A1 ES 350523A1 ES 350523 A ES350523 A ES 350523A ES 350523 A ES350523 A ES 350523A ES 350523 A1 ES350523 A1 ES 350523A1
- Authority
- ES
- Spain
- Prior art keywords
- alpha
- formula
- compound
- given above
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 abstract 8
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 abstract 7
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 4
- ZWEHNKRNPOVVGH-UHFFFAOYSA-N 2-Butanone Chemical compound CCC(C)=O ZWEHNKRNPOVVGH-UHFFFAOYSA-N 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- -1 nitro, amino, hydroxy Chemical group 0.000 abstract 3
- 229910000027 potassium carbonate Inorganic materials 0.000 abstract 3
- NLKNQRATVPKPDG-UHFFFAOYSA-M potassium iodide Chemical compound [K+].[I-] NLKNQRATVPKPDG-UHFFFAOYSA-M 0.000 abstract 3
- QWBBPBRQALCEIZ-UHFFFAOYSA-N 2,3-dimethylphenol Chemical compound CC1=CC=CC(O)=C1C QWBBPBRQALCEIZ-UHFFFAOYSA-N 0.000 abstract 2
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 229910021529 ammonia Inorganic materials 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- LHGVFZTZFXWLCP-UHFFFAOYSA-N guaiacol Chemical compound COC1=CC=CC=C1O LHGVFZTZFXWLCP-UHFFFAOYSA-N 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 239000004215 Carbon black (E152) Substances 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- PIICEJLVQHRZGT-UHFFFAOYSA-N Ethylenediamine Chemical class NCCN PIICEJLVQHRZGT-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000004423 acyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000000812 cholinergic antagonist Substances 0.000 abstract 1
- 230000000911 decarboxylating effect Effects 0.000 abstract 1
- 238000006114 decarboxylation reaction Methods 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 229960001867 guaiacol Drugs 0.000 abstract 1
- 229930195733 hydrocarbon Natural products 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
- 229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 150000002462 imidazolines Chemical class 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 229940100662 nasal drops Drugs 0.000 abstract 1
- NWVVVBRKAWDGAB-UHFFFAOYSA-N p-methoxyphenol Chemical compound COC1=CC=C(O)C=C1 NWVVVBRKAWDGAB-UHFFFAOYSA-N 0.000 abstract 1
- 229940083254 peripheral vasodilators imidazoline derivative Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229920006395 saturated elastomer Polymers 0.000 abstract 1
- 229930195734 saturated hydrocarbon Natural products 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
- 229930195735 unsaturated hydrocarbon Natural products 0.000 abstract 1
- 230000003639 vasoconstrictive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/22—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEN0030055 | 1967-02-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES350523A1 true ES350523A1 (es) | 1969-05-01 |
Family
ID=7345361
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES350523A Expired ES350523A1 (es) | 1967-02-23 | 1968-02-15 | Procedimiento para la fabricacion de ariloxi-isoalquil-del-ta2-imidazolinas y sus sales de acidos de adicion. |
Country Status (15)
| Country | Link |
|---|---|
| AT (1) | AT280277B (en, 2012) |
| BE (1) | BE711062A (en, 2012) |
| CH (1) | CH529766A (en, 2012) |
| DK (1) | DK127331B (en, 2012) |
| ES (1) | ES350523A1 (en, 2012) |
| FI (1) | FI49612C (en, 2012) |
| FR (2) | FR7361M (en, 2012) |
| GB (1) | GB1181356A (en, 2012) |
| IL (1) | IL29445A (en, 2012) |
| IT (1) | IT1062055B (en, 2012) |
| LU (1) | LU55443A1 (en, 2012) |
| NL (1) | NL156691B (en, 2012) |
| NO (1) | NO122530B (en, 2012) |
| SE (1) | SE341631B (en, 2012) |
| YU (1) | YU32924B (en, 2012) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5395968A (en) * | 1976-12-20 | 1978-08-22 | Wellcome Found | Imidazoline compounds |
| US4226876A (en) * | 1976-12-20 | 1980-10-07 | Burroughs Wellcome Co. | Arthropodicidal imidazoline derivatives |
| ZA787351B (en) * | 1978-06-19 | 1980-08-27 | Wellcome Found | Imidazolines,their preparation,intermediates therefor,and pesticidal formulations and use of the imidazolines |
| EP0011596B1 (de) | 1978-10-09 | 1981-12-30 | Ciba-Geigy Ag | Neue 2-(alpha-Phenoxy-alkyl)-imidazoline und ihre Salze, deren Herstellung und Verwendung sowie sie enthaltende Mittel zur Bekämpfung von pflanzenschädlichen und tierparasitären Milben |
| WO2009003868A2 (en) * | 2007-07-02 | 2009-01-08 | F. Hoffmann-La Roche Ag | 2 -imidazolines having a good affinity to the trace amine associated receptors (taars) |
-
1968
- 1968-02-07 CH CH178368A patent/CH529766A/de not_active IP Right Cessation
- 1968-02-08 SE SE165668A patent/SE341631B/xx unknown
- 1968-02-09 IL IL2944568A patent/IL29445A/en unknown
- 1968-02-09 LU LU55443D patent/LU55443A1/xx unknown
- 1968-02-14 AT AT140068A patent/AT280277B/de not_active IP Right Cessation
- 1968-02-15 ES ES350523A patent/ES350523A1/es not_active Expired
- 1968-02-17 NO NO60868A patent/NO122530B/no unknown
- 1968-02-20 FI FI44768A patent/FI49612C/fi active
- 1968-02-20 YU YU38368A patent/YU32924B/xx unknown
- 1968-02-21 BE BE711062D patent/BE711062A/xx not_active IP Right Cessation
- 1968-02-22 IT IT1308368A patent/IT1062055B/it active
- 1968-02-22 DK DK69668A patent/DK127331B/da not_active IP Right Cessation
- 1968-02-23 FR FR141118A patent/FR7361M/fr not_active Expired
- 1968-02-23 NL NL6802611A patent/NL156691B/xx unknown
- 1968-02-23 GB GB887568A patent/GB1181356A/en not_active Expired
- 1968-02-23 FR FR1555168D patent/FR1555168A/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DK127331B (da) | 1973-10-22 |
| BE711062A (en, 2012) | 1968-07-01 |
| IT1062055B (it) | 1983-06-25 |
| AT280277B (de) | 1970-04-10 |
| SE341631B (en, 2012) | 1972-01-10 |
| FR1555168A (en, 2012) | 1969-01-24 |
| NL156691B (nl) | 1978-05-16 |
| NL6802611A (en, 2012) | 1968-08-26 |
| FI49612C (fi) | 1975-08-11 |
| FR7361M (en, 2012) | 1969-10-20 |
| CH529766A (de) | 1972-10-31 |
| LU55443A1 (en, 2012) | 1968-04-16 |
| IL29445A (en) | 1971-08-25 |
| YU32924B (en) | 1975-12-31 |
| YU38368A (en) | 1975-06-30 |
| NO122530B (en, 2012) | 1971-07-12 |
| GB1181356A (en) | 1970-02-18 |
| FI49612B (en, 2012) | 1975-04-30 |
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