ES343026A1 - Racemization of d(+) 6-phenyl-2,3,5,6-tetrahydroimidazo [2,1-b] thiazole - Google Patents

Racemization of d(+) 6-phenyl-2,3,5,6-tetrahydroimidazo [2,1-b] thiazole

Info

Publication number
ES343026A1
ES343026A1 ES343026A ES343026A ES343026A1 ES 343026 A1 ES343026 A1 ES 343026A1 ES 343026 A ES343026 A ES 343026A ES 343026 A ES343026 A ES 343026A ES 343026 A1 ES343026 A1 ES 343026A1
Authority
ES
Spain
Prior art keywords
tetrahydroimidazo
racemization
thiazole
phenyl
lcompound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES343026A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ES343026A1 publication Critical patent/ES343026A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

dl - 6 - Phenyl - 2,3,5,6 - tetrahydroimidazo[2,1-b]thiazole is obtained in a process which comprises heating the corresponding d or lcompound with a strong non-aqueous base, e.g. sodium hydride, sodium amide or potassium t-butylate. The racemization is preferably effected between 20 DEG and 120 DEG C. Subsequently the racemate may be resolved by the usual procedures e.g. with d-10-camphorsulphonic acid.
ES343026A 1966-07-14 1967-07-14 Racemization of d(+) 6-phenyl-2,3,5,6-tetrahydroimidazo [2,1-b] thiazole Expired ES343026A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56510166A 1966-07-14 1966-07-14

Publications (1)

Publication Number Publication Date
ES343026A1 true ES343026A1 (en) 1968-10-01

Family

ID=24257219

Family Applications (1)

Application Number Title Priority Date Filing Date
ES343026A Expired ES343026A1 (en) 1966-07-14 1967-07-14 Racemization of d(+) 6-phenyl-2,3,5,6-tetrahydroimidazo [2,1-b] thiazole

Country Status (11)

Country Link
BE (1) BE701314A (en)
BR (1) BR6790822D0 (en)
CH (1) CH479608A (en)
DE (1) DE1645985A1 (en)
ES (1) ES343026A1 (en)
GB (1) GB1120406A (en)
IL (1) IL28044A (en)
IT (1) IT1061853B (en)
NL (1) NL6708056A (en)
SE (1) SE319487B (en)
YU (1) YU31916B (en)

Also Published As

Publication number Publication date
IL28044A (en) 1971-08-25
YU139667A (en) 1973-08-31
GB1120406A (en) 1968-07-17
BR6790822D0 (en) 1973-09-06
SE319487B (en) 1970-01-19
BE701314A (en) 1968-01-15
IT1061853B (en) 1983-04-30
NL6708056A (en) 1968-01-15
YU31916B (en) 1974-02-28
CH479608A (en) 1969-10-15
DE1645985A1 (en) 1970-08-06

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