ES338376A1 - Procedimiento para la preparacion de 5-metil-10 (2'-dimeti-laminopropil-1')-10-11-dihidro-11-oxo-5h-dibenzo (b, e)-1, 4-diacepina, asi como de sales de adicion de acido de la mis-ma. - Google Patents
Procedimiento para la preparacion de 5-metil-10 (2'-dimeti-laminopropil-1')-10-11-dihidro-11-oxo-5h-dibenzo (b, e)-1, 4-diacepina, asi como de sales de adicion de acido de la mis-ma.Info
- Publication number
- ES338376A1 ES338376A1 ES338376A ES338376A ES338376A1 ES 338376 A1 ES338376 A1 ES 338376A1 ES 338376 A ES338376 A ES 338376A ES 338376 A ES338376 A ES 338376A ES 338376 A1 ES338376 A1 ES 338376A1
- Authority
- ES
- Spain
- Prior art keywords
- methyl
- diazepine
- dibenzo
- oxo
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- BUZIDFSLFHEORD-UHFFFAOYSA-N 11-methyl-5h-benzo[b][1,4]benzodiazepin-6-one Chemical compound N1C(=O)C2=CC=CC=C2N(C)C2=CC=CC=C21 BUZIDFSLFHEORD-UHFFFAOYSA-N 0.000 abstract 2
- ROSDSFDQCJNGOL-UHFFFAOYSA-N Dimethylamine Chemical compound CNC ROSDSFDQCJNGOL-UHFFFAOYSA-N 0.000 abstract 2
- VQFAIAKCILWQPZ-UHFFFAOYSA-N bromoacetone Chemical compound CC(=O)CBr VQFAIAKCILWQPZ-UHFFFAOYSA-N 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
- NCXUNZWLEYGQAH-UHFFFAOYSA-N 1-(dimethylamino)propan-2-ol Chemical compound CC(O)CN(C)C NCXUNZWLEYGQAH-UHFFFAOYSA-N 0.000 abstract 1
- PBKGYWLWIJLDGZ-UHFFFAOYSA-N 2-(dimethylamino)propan-1-ol Chemical compound OCC(C)N(C)C PBKGYWLWIJLDGZ-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000001035 methylating effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000007911 parenteral administration Methods 0.000 abstract 1
- 229910000033 sodium borohydride Inorganic materials 0.000 abstract 1
- 239000012279 sodium borohydride Substances 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/38—[b, e]- or [b, f]-condensed with six-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH436666A CH481117A (de) | 1966-03-25 | 1966-03-25 | Verfahren zur Herstellung von 5-Methyl-10-(2'-dimethylaminopropyl-1')-10,11-dihydro-11--oxo-5H-dibenzo(b,e)-1,4-diazepin sowie von Säure-Additionssalzen davon |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES338376A1 true ES338376A1 (es) | 1968-10-16 |
Family
ID=4274751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES338376A Expired ES338376A1 (es) | 1966-03-25 | 1967-03-22 | Procedimiento para la preparacion de 5-metil-10 (2'-dimeti-laminopropil-1')-10-11-dihidro-11-oxo-5h-dibenzo (b, e)-1, 4-diacepina, asi como de sales de adicion de acido de la mis-ma. |
Country Status (13)
| Country | Link |
|---|---|
| AT (4) | AT269161B (pm) |
| BE (1) | BE695847A (pm) |
| CH (4) | CH481118A (pm) |
| DE (1) | DE1720014A1 (pm) |
| DK (1) | DK113018B (pm) |
| ES (1) | ES338376A1 (pm) |
| FR (1) | FR6289M (pm) |
| GB (1) | GB1169804A (pm) |
| GR (1) | GR36286B (pm) |
| IL (1) | IL27629A (pm) |
| NL (1) | NL6704326A (pm) |
| NO (1) | NO120477B (pm) |
| SE (1) | SE334365B (pm) |
-
1966
- 1966-03-25 CH CH1379469A patent/CH481118A/de not_active IP Right Cessation
- 1966-03-25 CH CH1379669A patent/CH481119A/de not_active IP Right Cessation
- 1966-03-25 CH CH1379569A patent/CH482694A/de not_active IP Right Cessation
- 1966-03-25 CH CH436666A patent/CH481117A/de not_active IP Right Cessation
-
1967
- 1967-03-17 AT AT249568A patent/AT269161B/de active
- 1967-03-17 IL IL2762967A patent/IL27629A/en unknown
- 1967-03-17 GB GB02542/67A patent/GB1169804A/en not_active Expired
- 1967-03-17 AT AT249468A patent/AT269160B/de active
- 1967-03-17 DE DE19671720014 patent/DE1720014A1/de active Pending
- 1967-03-17 AT AT249368A patent/AT269159B/de active
- 1967-03-17 AT AT260967A patent/AT269147B/de active
- 1967-03-17 SE SE377667A patent/SE334365B/xx unknown
- 1967-03-20 FR FR99433A patent/FR6289M/fr not_active Expired
- 1967-03-21 NO NO16740967A patent/NO120477B/no unknown
- 1967-03-21 DK DK149567A patent/DK113018B/da unknown
- 1967-03-21 BE BE695847D patent/BE695847A/xx unknown
- 1967-03-22 ES ES338376A patent/ES338376A1/es not_active Expired
- 1967-03-22 GR GR670136286A patent/GR36286B/el unknown
- 1967-03-23 NL NL6704326A patent/NL6704326A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH481117A (de) | 1969-11-15 |
| SE334365B (pm) | 1971-04-26 |
| GB1169804A (en) | 1969-11-05 |
| BE695847A (pm) | 1967-09-21 |
| AT269161B (de) | 1969-03-10 |
| DK113018B (da) | 1969-02-10 |
| DE1720014A1 (de) | 1971-05-19 |
| FR6289M (pm) | 1968-09-02 |
| CH481119A (de) | 1969-11-15 |
| AT269159B (de) | 1969-03-10 |
| GR36286B (el) | 1969-01-20 |
| CH481118A (de) | 1969-11-15 |
| NL6704326A (pm) | 1967-09-26 |
| NO120477B (pm) | 1970-10-26 |
| IL27629A (en) | 1971-01-28 |
| AT269160B (de) | 1969-03-10 |
| CH482694A (de) | 1969-12-15 |
| AT269147B (de) | 1969-03-10 |
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