ES337458A1 - Procedure for the production of indollic derivatives. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the production of indollic derivatives. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES337458A1
ES337458A1 ES337458A ES337458A ES337458A1 ES 337458 A1 ES337458 A1 ES 337458A1 ES 337458 A ES337458 A ES 337458A ES 337458 A ES337458 A ES 337458A ES 337458 A1 ES337458 A1 ES 337458A1
Authority
ES
Spain
Prior art keywords
signifies
translation
procedure
production
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES337458A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES337458A1 publication Critical patent/ES337458A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for the production of indole derivatives of formula I a, **(See formula)** wherein one of the symbols R1 and R2 signifies a hydrogen atom, the other symbol signifies a hydrogen atom or a methyl radical, and R'3 signifies the isopropyl, cyclopropyl or butyl sec radical, characterized in that an imine is reduced of formula II, **(See formula)** wherein R1 and R2 have the meanings indicated above, and signifies methyl, R5 signifies methyl or ethyl, or R4 and R5 together signify the ethylenic chain. (Machine-translation by Google Translate, not legally binding)
ES337458A 1966-06-21 1967-03-02 Procedure for the production of indollic derivatives. (Machine-translation by Google Translate, not legally binding) Expired ES337458A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH898666A CH469002A (en) 1966-06-21 1966-06-21 Process for the production of new indole derivatives

Publications (1)

Publication Number Publication Date
ES337458A1 true ES337458A1 (en) 1968-03-01

Family

ID=4347068

Family Applications (1)

Application Number Title Priority Date Filing Date
ES337458A Expired ES337458A1 (en) 1966-06-21 1967-03-02 Procedure for the production of indollic derivatives. (Machine-translation by Google Translate, not legally binding)

Country Status (7)

Country Link
AT (1) AT266822B (en)
CH (1) CH469002A (en)
CS (1) CS156407B2 (en)
DK (1) DK124612B (en)
ES (1) ES337458A1 (en)
FI (1) FI47366C (en)
SE (1) SE308110B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1980000152A1 (en) * 1978-07-03 1980-02-07 Sandoz Ag 3-aminopropoxy-aryl derivates,preparation and use thereof
EP0013878A1 (en) * 1979-01-18 1980-08-06 Sandoz Ag 3-Aminopropoxyaryl derivatives, their preparation and pharmaceutical compositions containing them
CN1681495B (en) 2002-08-19 2010-05-12 辉瑞产品公司 Combination therapy for hyperplasia diseases
GT200600381A (en) 2005-08-25 2007-03-28 ORGANIC COMPOUNDS
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
JP5498168B2 (en) 2006-12-01 2014-05-21 ブリストル−マイヤーズ スクイブ カンパニー N-((3-Benzyl) -2,2- (bis-phenyl) -propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular disease
WO2008112287A1 (en) 2007-03-12 2008-09-18 Nektar Therapeutics Oligomer-beta blocker conjugates
EP2986599A1 (en) 2013-04-17 2016-02-24 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
BR112021013807A2 (en) 2019-01-18 2021-11-30 Astrazeneca Ab pcsk9 inhibitors and their methods of use

Also Published As

Publication number Publication date
AT266822B (en) 1968-12-10
FI47366B (en) 1973-07-31
CS156407B2 (en) 1974-07-24
SE308110B (en) 1969-02-03
FI47366C (en) 1973-11-12
DK124612B (en) 1972-11-06
CH469002A (en) 1969-02-28

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