ES323695A1 - Procedure for the production of spiro-succinimide derivatives. (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the production of spiro-succinimide derivatives. (Machine-translation by Google Translate, not legally binding)
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AGfiledCriticalSandoz AG
Publication of ES323695A1publicationCriticalpatent/ES323695A1/en
C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
C07D471/10—Spiro-condensed systems
Landscapes
Chemical & Material Sciences
(AREA)
Organic Chemistry
(AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Nitrogen Condensed Heterocyclic Rings
(AREA)
Pyrrole Compounds
(AREA)
Abstract
Process for the production of spiro-succinimide derivatives of 10,11-dihydro-5H-dibenzo [b, f] acepine of formula I, ** (See formula) ** wherein R 1 signifies an alkyl or lower aralkyl radical, R 2 signifies a hydrogen atom or a lower alkyl radical, and R 3 signifies a hydrogen atom or the methyl radical, characterized in that a compound of the formula is heated up to 120-220º C. II, ** (See formula) ** wherein R3 has the meaning indicated above, and X signifies the acid radical of a reactive ester, in the presence of an acid-binding agent with a 2,8-diazaspiro [4,5] decan-1,3-dione of formula III, ** (See formula) ** wherein R1 and R2 have the meanings indicated above. (Machine-translation by Google Translate, not legally binding)
ES0323695A1965-03-031966-03-01Procedure for the production of spiro-succinimide derivatives. (Machine-translation by Google Translate, not legally binding)
ExpiredES323695A1
(en)
Procedure for the obtaining of derivatives of 9,10-dihydro-4h-benzo (4,5) ciclohepta (1,2-b) tiofeno. (Machine-translation by Google Translate, not legally binding)