ES323695A1 - Procedure for the production of spiro-succinimide derivatives. (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the production of spiro-succinimide derivatives. (Machine-translation by Google Translate, not legally binding)
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Sandoz AG
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Sandoz AG
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C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
C07D471/10—Spiro-condensed systems
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Chemical & Material Sciences
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Organic Chemistry
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
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Nitrogen Condensed Heterocyclic Rings
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Pyrrole Compounds
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Abstract
Process for the production of spiro-succinimide derivatives of 10,11-dihydro-5H-dibenzo [b, f] acepine of formula I, ** (See formula) ** wherein R 1 signifies an alkyl or lower aralkyl radical, R 2 signifies a hydrogen atom or a lower alkyl radical, and R 3 signifies a hydrogen atom or the methyl radical, characterized in that a compound of the formula is heated up to 120-220º C. II, ** (See formula) ** wherein R3 has the meaning indicated above, and X signifies the acid radical of a reactive ester, in the presence of an acid-binding agent with a 2,8-diazaspiro [4,5] decan-1,3-dione of formula III, ** (See formula) ** wherein R1 and R2 have the meanings indicated above. (Machine-translation by Google Translate, not legally binding)
ES0323695A1965-03-031966-03-01Procedure for the production of spiro-succinimide derivatives. (Machine-translation by Google Translate, not legally binding)
ExpiredES323695A1
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