ES320817A1 - Procedure for recovery of tetracyclines from fermentation calds. (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for recovery of tetracyclines from fermentation calds. (Machine-translation by Google Translate, not legally binding)
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Glaxochem SpA
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Ankerfarm SpA
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Publication of ES320817A1publicationCriticalpatent/ES320817A1/en
Preparation Of Compounds By Using Micro-Organisms
(AREA)
Micro-Organisms Or Cultivation Processes Thereof
(AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems
(AREA)
Abstract
Process for recovering tetracyclines from the fermentation broths, comprising filtering the mycelium-free broth, adjusting the pH of the broth to a pH between 0.5 and 6.0, adding cupric ions and a surface active agent to precipitate a copper complex of the tetracycline antibiotic, filtering said cupric complex of tetracycline, dissolving said precipitate of said tetracycline cupric complex in an organic solvent that is immiscible with water, and eliminating the cupric ions of said tetracycline dissolved cupric complex by aqueous extraction of said organic solution with an aqueous solution of a chelating agent having a greater propensity to cupric ions than to tetracycline and which removes the cupric ions from said aqueous solution, whereby a solution of tetracycline in said solvent is obtained organic. (Machine-translation by Google Translate, not legally binding)
ES0320817A1965-02-031965-12-16Procedure for recovery of tetracyclines from fermentation calds. (Machine-translation by Google Translate, not legally binding)
ExpiredES320817A1
(en)
Procedure for the preparation of salts from fusºdic acid with antibiotics of the tetracycline series (Machine-translation by Google Translate, not legally binding)
Procedure to recover nistatin from the micelly of the whole body in which nistatin has been produced. (Machine-translation by Google Translate, not legally binding)
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