ES318372A1 - Procedure for the obtaining of phenyl carbinols - rent with substituteed nuclei, which have coleretic activity. (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the obtaining of phenyl carbinols - rent with substituteed nuclei, which have coleretic activity. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES318372A1
ES318372A1 ES0318372A ES318372A ES318372A1 ES 318372 A1 ES318372 A1 ES 318372A1 ES 0318372 A ES0318372 A ES 0318372A ES 318372 A ES318372 A ES 318372A ES 318372 A1 ES318372 A1 ES 318372A1
Authority
ES
Spain
Prior art keywords
coleretic
translation
activity
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0318372A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratorio Guidotti SpA
Original Assignee
Laboratorio Guidotti SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorio Guidotti SpA filed Critical Laboratorio Guidotti SpA
Publication of ES318372A1 publication Critical patent/ES318372A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with no unsaturation outside the aromatic ring
    • C07C39/06—Alkylated phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Process for obtaining phenyl-alkyl carbinols with substituted nuclei, which have coleretic activity, according to the general formula: ** (See formula) ** When R '= -C4H9n so ** (See formula) ** and when R '= ** (See formula) ** so ** (See formula) ** characterized in that an aromatic aldehyde, having as substitutes in the benzene ring an -OH, which may be either free or esterified with an acetic or benzene radical, and possibly also other alkoxyl groups, is bound to react with an alkyl-halogenic of magnesium, or a cycloalkyl-halogºnico in suitable solvents, and decomposing the complex thus obtained with dilute aqueous acids, or with a solution of NH 4 Cl, finally isolating the formed carbinol. (Machine-translation by Google Translate, not legally binding)
ES0318372A 1964-10-09 1965-10-09 Procedure for the obtaining of phenyl carbinols - rent with substituteed nuclei, which have coleretic activity. (Machine-translation by Google Translate, not legally binding) Expired ES318372A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT5214664 1964-10-09

Publications (1)

Publication Number Publication Date
ES318372A1 true ES318372A1 (en) 1966-04-16

Family

ID=11276436

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0318372A Expired ES318372A1 (en) 1964-10-09 1965-10-09 Procedure for the obtaining of phenyl carbinols - rent with substituteed nuclei, which have coleretic activity. (Machine-translation by Google Translate, not legally binding)

Country Status (4)

Country Link
BR (1) BR6573775D0 (en)
ES (1) ES318372A1 (en)
IL (1) IL24405A (en)
SE (1) SE341191B (en)

Also Published As

Publication number Publication date
SE341191B (en) 1971-12-20
IL24405A (en) 1969-06-25
BR6573775D0 (en) 1973-08-02

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