ES313318A1 - Procedure for the obtaining amines of the acid 1,6-dimethyl delta 8,9-ergolen-8-carboxylic. (Machine-translation by Google Translate, not legally binding)
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Procedure for the obtaining amines of the acid 1,6-dimethyl delta 8,9-ergolen-8-carboxylic. (Machine-translation by Google Translate, not legally binding)
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Sandoz AG
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Sandoz AG
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Publication of ES313318A1publicationCriticalpatent/ES313318A1/en
Process for the preparation of amides of 1,6-dimethyl Δ 8,9-ergolen-8-carbosyl acid of the general formula I, ** (See formula) ** wherein R 1 signifies a hydrogen atom or an alkyl radical containing from 1 to 4 carbon atoms inclusive, and R 2 signifies an alkyl radical containing from 1 to 4 carbon atoms inclusive, a hydroxyalkyl radical containing from 2 to 6 carbon atoms inclusive, a cycloalkyl radical containing from 4 to 6 carbon atoms inclusive or a piperidyl-4 radical substituted in the 1-position by an alkyl radical containing from 1 to 4 carbon atoms inclusive, or R1 and R2 together with the nitrogen atom forms a piperidino radical which can optionally be bound with a hydroxy radical, and its acid addition salts, characterized in that compounds of the general formula II are reacted, ** (See formula) ** wherein R1 and R2 have the meanings indicated above, in liquid ammonia with methyl iodide in the presence of a basic condensation agent. (Machine-translation by Google Translate, not legally binding)
ES0313318A1964-05-261965-05-24Procedure for the obtaining amines of the acid 1,6-dimethyl delta 8,9-ergolen-8-carboxylic. (Machine-translation by Google Translate, not legally binding)
ExpiredES313318A1
(en)
Procedure for the obtaining amines of the acid 1,6-dimethyl delta 8,9-ergolen-8-carboxylic. (Machine-translation by Google Translate, not legally binding)
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