ES287413A1 - Procedure for preparing new acepinic derivatives (Machine-translation by Google Translate, not legally binding) - Google Patents

Abstract

Process for preparing new acephenic derivatives, characterized in that compounds of the general formula I are prepared ** (See formula) ** in which R means hydrogen, a lower alkyl radical or an aralkyl radical, Z means a straight or branched chain alkylene radical having 2 to 6 carbon atoms, and Am means a lower dual-kinamic group, whose alkyl radicals may be linked to each other directly or by means of a lower alkyliminic group, or a lower alkylaminic group, hydrogenating a compound of the general formula II ** (See formula) ** in which Am 'means a radical corresponding to the definition of Am, with the exception of a lower alkylaminic group, or a lower N-arylmethyl-alkylaminic group, R 'means a lower alkyl radical or an aralkyl radical and Z has the meaning stated above, up to absorption of a quantity of hydrogen fundamentally double that of the molar or, in the case of an arylmethyl radical of Am ', triple that of the molar, dissociating, if desired, the radical R' by acidolysis and/or reacting, if If desired, a compound containing a lower dialkylamine radical Am 'with a carboxylic monoester halide or phosgene, converting it to a compound which, instead of an alkyl radical of the Am' group, contains a carboxylic monoester radical or the chlorocarbonyl radical , and hydrolyzing this last compound and finally, if desired, converting the compound of the general formula I obtained in a salt with an inorganic or organic acid. (Machine-translation by Google Translate, not legally binding)