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Boehringer Ingelheim Pharma GmbH and Co KG
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Dr Karl Thomae GmbH
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Publication date
Application filed by Dr Karl Thomae GmbHfiledCriticalDr Karl Thomae GmbH
Priority to ES283982ApriorityCriticalpatent/ES283982A1/en
Publication of ES283982A1publicationCriticalpatent/ES283982A1/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
Procedure for obtaining new derivatives of the formulas ajmaline ** (See formula) ** respectively ** (See formula) ** where R represents a straight or branched chain residue of alkyl, alkenyl or alkynyl with 3 to 5 carbon atoms and X represents the anion of a physiologically tolerable inorganic or organic acid, characterized in that the ajmaline is transformed with a compound of the formula RX - in which R has the indicated meaning and X represents a halogen atom or the anion of an aromatic sulfonic acid - advantageously in the presence of an inert organic solvent and advantageously at temperatures of 0 to 100º C, and eventually transformed then the salts thus obtained of the formula I, in which X represents a halogen atom or the anion of an aromatic sulfonic acid, by means of aqueous alkalis, in aldehydic bases of the formula II, and optionally these are transformed, with an inorganic acid or physiologically tolerable organic, in quaternary salts of the formula I. (Machine-translation by Google Translate, not legally binding)
ES283982A1963-01-071963-01-07Procedure for obtaining new derivatives from ajmalina (Machine-translation by Google Translate, not legally binding)
ExpiredES283982A1
(en)
Procedure for the preparation of derivatives of 4-thermoamine-methyl-7-hydroxy-cumarine. (Machine-translation by Google Translate, not legally binding)