ES2791873T3 - Detección de modificaciones químicas en ácidos nucleicos - Google Patents
Detección de modificaciones químicas en ácidos nucleicos Download PDFInfo
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- ES2791873T3 ES2791873T3 ES14851691T ES14851691T ES2791873T3 ES 2791873 T3 ES2791873 T3 ES 2791873T3 ES 14851691 T ES14851691 T ES 14851691T ES 14851691 T ES14851691 T ES 14851691T ES 2791873 T3 ES2791873 T3 ES 2791873T3
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- rna
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/01—Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
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- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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| PCT/US2014/059489 WO2015054247A1 (en) | 2013-10-07 | 2014-10-07 | Detection of chemical modifications in nucleic acids |
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| ES2791873T3 true ES2791873T3 (es) | 2020-11-06 |
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| US12195788B2 (en) * | 2017-01-12 | 2025-01-14 | University Of Central Florida Research Foundation, Inc. | High-throughput and single nucleotide resolution techniques for the determination of RNA post-transcriptional modifications |
| WO2018144782A1 (en) * | 2017-02-01 | 2018-08-09 | The Translational Genomics Research Institute | Methods of detecting somatic and germline variants in impure tumors |
| RU2659025C1 (ru) * | 2017-06-14 | 2018-06-26 | Общество с ограниченной ответственностью "ЛЭНДИГРАД" | Способы кодирования и декодирования информации |
| CN109517889B (zh) * | 2017-09-18 | 2022-04-05 | 苏州吉赛基因测序科技有限公司 | 一种基于高通量测序分析寡核苷酸序列杂质的方法及应用 |
| WO2019109046A1 (en) | 2017-11-30 | 2019-06-06 | Arrakis Therapeutics, Inc. | Nucleic acid-binding photoprobes and uses thereof |
| WO2022094863A1 (zh) * | 2020-11-05 | 2022-05-12 | 清华大学 | 一种全转录组水平rna结构检测方法及其应用 |
| CN114438168B (zh) * | 2020-11-05 | 2024-10-22 | 寻鲸生科(北京)智能技术有限公司 | 一种全转录组水平rna结构检测方法及其应用 |
| CN114507721B (zh) * | 2020-11-16 | 2024-04-09 | 寻鲸生科(北京)智能技术有限公司 | 一种全转录组rna结构探测的方法及其应用 |
| CA3200114C (en) * | 2020-11-18 | 2024-06-04 | Xforest Therapeutics Co., Ltd. | Rna probe for mutation profiling and use thereof |
| US11795500B2 (en) | 2021-08-19 | 2023-10-24 | Eclipse Bioinnovations, Inc. | Methods for detecting RNA binding protein complexes |
| WO2023235820A1 (en) * | 2022-06-03 | 2023-12-07 | Eclipse Bioinnovations, Inc. | Methods for obtaining rna secondary structure of lnp-encapsulated rna |
| WO2025137453A1 (en) * | 2023-12-20 | 2025-06-26 | New England Biolabs, Inc. | Compositions, methods, kits, and instruments for analyzing rna structure |
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| US20070196832A1 (en) * | 2006-02-22 | 2007-08-23 | Efcavitch J William | Methods for mutation detection |
| WO2007145940A2 (en) | 2006-06-05 | 2007-12-21 | The University Of North Carolina At Chapel Hill | High-throughput rna structure analysis |
| EP2053131A1 (en) * | 2007-10-19 | 2009-04-29 | Ludwig-Maximilians-Universität München | Method for determining methylation at deoxycytosine residues |
| US20130288917A1 (en) * | 2010-10-21 | 2013-10-31 | The Board Of Trustees Of The Leland Stanford Junior University | Rapid High Resolution, High Throughput RNA Structure, RNA-Macromolecular Interaction, and RNA-Small Molecule Interaction Mapping |
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| JP2016535983A (ja) | 2016-11-24 |
| US20160244818A1 (en) | 2016-08-25 |
| EP3055413A1 (en) | 2016-08-17 |
| US10240188B2 (en) | 2019-03-26 |
| WO2015054247A1 (en) | 2015-04-16 |
| JP6612220B2 (ja) | 2019-11-27 |
| EP3055413B1 (en) | 2020-01-08 |
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