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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Publication of ES276452A1publicationCriticalpatent/ES276452A1/en
C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
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Chemical & Material Sciences
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Organic Chemistry
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Other In-Based Heterocyclic Compounds
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
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Abstract
Process for the production of isoquinoline derivatives, characterized in that it comprises condensing in the presence of a condensation agent a compound of the formula ** (See formula) ** where A- represents an anion, with a benzaldehyde, halosubstituted in the nucleus, of the formula ** (See formula) ** where R is a halogen atom and n is an integer value from 1 to 3, inclusive, and hydrogenating the condensation product, if desired, to obtain correspondingly substituted 1-phenethyl-2-methyl-1, 2,3,4-tetrahydroisoquinoline. (Machine-translation by Google Translate, not legally binding)
ES276452A1961-04-141962-04-13Procedure for the manufacture of isoquinoline derivatives (Machine-translation by Google Translate, not legally binding)
ExpiredES276452A1
(en)
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