ES2711658A1 - System of prediction and simulation of results after laser iridoplasties (laser treatments of the iris) (Machine-translation by Google Translate, not legally binding) - Google Patents

System of prediction and simulation of results after laser iridoplasties (laser treatments of the iris) (Machine-translation by Google Translate, not legally binding) Download PDF

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ES2711658A1
ES2711658A1 ES201700758A ES201700758A ES2711658A1 ES 2711658 A1 ES2711658 A1 ES 2711658A1 ES 201700758 A ES201700758 A ES 201700758A ES 201700758 A ES201700758 A ES 201700758A ES 2711658 A1 ES2711658 A1 ES 2711658A1
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results
laser
prediction
color
simulation
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Ruiz Pedro Grimaldos
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    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16Z—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS, NOT OTHERWISE PROVIDED FOR
    • G16Z99/00—Subject matter not provided for in other main groups of this subclass
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/08—Devices or methods enabling eye-patients to replace direct visual perception by another kind of perception

Abstract

The invention is an automatic system for predicting and simulating cosmetic results after laser iridoplasties (laser treatments of the iris), which consists of two computer programs, one for prediction and the other for simulation, and a high definition image capture equipment for the eyes and the face. The prediction system is based on the "Theory of the two genes of the color of eyes", and uses the "Classification of degrees of pigmentation of the iris of Grimaldos" and a base of real images of patients already treated with the same personal and family phenotype., and treated with the same types of lasers. The system calculates probability percentages of the different types of cosmetic result. The simulation system generates a three-dimensional interactive model of the patient's eyes and face, and uses a color palette based on the "Grimaldos Iris Colors 60 Scale". The simulation system calculates the influence of ambient lighting and the observation distance on the size of the pupils and on the appearance of the color of the eyes. (Machine-translation by Google Translate, not legally binding)

Description

DESCRIPCIONDESCRIPTION

Sistema de prediction y simulation de resultados tras iridoplastias laser (tratamientos con laser del iris).System of prediction and simulation of results after laser iridoplasties (laser treatments of the iris).

Sector de la tecnicaSector of the technique

El invento pertenece al sector de los sistemas de prediction y simulation de los resultados de intervenciones quirurgicas mediante cirugla o laser. Como ejemplos podemos citar los sistemas de prediction y simulation tras operaciones de nariz (rinoplastias) o intervenciones con laser para corregir la miopia (cirugla refractiva).The invention belongs to the sector of the systems of prediction and simulation of the results of surgical interventions by surgery or laser. As examples we can mention the prediction and simulation systems after nose operations (rhinoplasty) or laser interventions to correct myopia (refractive surgery).

Estado de la tecnicaState of the art

Actualmente, no existe ningun sistema de prediction y/o simulation de tratamientos con laser del iris, o iridoplastia laser. Esta tecnica trata las alteraciones o anomallas del pigmento del iris mediante el uso de diferentes tipos de laser oftalmologico.Currently, there is no system for prediction and / or simulation of laser treatments of the iris, or laser iridoplasty. This technique treats the alterations or anomalies of the iris pigment through the use of different types of ophthalmological laser.

Problema tecnico planteadoTechnical problem raised

El resultado final de la iridoplastia laser depende de varios factores, que son los siguientes:The final result of laser iridoplasty depends on several factors, which are the following:

- El estado inicial del iris, es decir, su apariencia original o fenotipo.- The initial state of the iris, that is, its original appearance or phenotype.

- Los antecedentes familiares de fenotipo.- Family history of phenotype.

- Los antecedentes familiares de genotipo.- Family history of genotype.

- Iluminacion ambiental- Environmental lighting

- Diametro pupilar- Pupillary diameter

- Distancia de observation- Observation distance

- Tipo de laser utilizado- Type of laser used

Los factores citados anteriormente determinan de forma decisiva el resultado cosmetico de la tecnica iridoplastia laser, por lo que no es posible realizar una prediction o simulation fiable sin tenerlos en cuenta.The aforementioned factors decisively determine the cosmetic result of the laser iridoplasty technique, so it is not possible to perform a reliable prediction or simulation without taking them into account.

Actualmente es obligatorio realizar una correcta prediction y simulation de los resultados antes de llevar a cabo cualquier tratamiento de cirugla o laser, especialmente con indication estetica. El paciente tiene derecho a solicitar una precision del resultado antes de tomar la decision de someterse al procedimiento, y esta documentacion debe formar parte a nivel legal del consentimiento informado.Currently it is mandatory to make a correct prediction and simulation of the results before carrying out any surgery or laser treatment, especially with aesthetic indication. The patient has the right to request a precision of the result before making the decision to submit to the procedure, and this documentation must be part of the legal level of the informed consent.

Soluciones que aporta el inventoSolutions provided by the invention

El invento consiste en la programacion de dos software: uno para predecir el resultado y otro para simularlo.The invention consists in the programming of two software: one to predict the result and another to simulate it.

El programa de prediction se basa en la "Teona de los dos genes del color de ojos" (verde y azul) y tiene en cuenta las siguientes variables: The prediction program is based on the "Theona of the two genes of the eye color" (green and blue) and takes into account the following variables:

- Sexo del paciente- Patient's sex

- Nivel de pigmentacion (l-IV) segun la clasificacion de Grimaldos (Fig 1)- Level of pigmentation (l-IV) according to the classification of Grimaldos (Fig 1)

- Color de piel: oscura o clara- Skin color: dark or light

- Color de cabello: castano o rubio- Hair color: brown or blonde

- Fenotipo de padre y madre de color de ojos (marron, verde o azul), color de piel (oscuro o clara) y color de cabello (castano o rubio)- Phenotype of father and mother with eye color (brown, green or blue), skin color (dark or light) and hair color (brown or blond)

Teniendo en cuenta las bases de la "Teona de los dos genes", el estado original de los ojos y el tipo de tratamiento con laser aplicado, el software calculara automaticamente una prediction del resultado estetico, utilizando una base de imagenes de resultados cosmeticos reales de pacientes con caracterlsticas de fenotipo y genotipo semejantes, y que recibieron tratamientos laser similares. De esta forma, la prediccion generada sera altamente fiable, y fidedigna con la realidad (Fig 2).Taking into account the bases of the "Theona of the two genes", the original state of the eyes and the type of laser treatment applied, the software will automatically calculate a prediction of the aesthetic result, using a base of images of actual cosmetic results of patients with similar phenotype and genotype characteristics, and who received similar laser treatments. In this way, the prediction generated will be highly reliable, and reliable with reality (Fig 2).

El programa de simulation consiste en generar un modelo artificial en 3D (tres dimensiones) del ojo del paciente y de su cara. Estas dos imagenes seran interactivas y podran ser modificadas por el explorador en los siguientes parametros:The simulation program consists of generating an artificial 3D model (three dimensions) of the patient's eye and face. These two images will be interactive and may be modified by the browser in the following parameters:

- Color del iris, a partir de una paleta de 60 colores (Escala de Grimaldos) (Fig 3)- Color of the iris, from a palette of 60 colors (Grimaldos Scale) (Fig 3)

- Nivel de iluminacion ambiental, que modifica el tamano de las pupilas y la apariencia del color del iris- Level of environmental lighting, which modifies the size of the pupils and the appearance of the color of the iris

- Distancia de observation, que influye en el aspecto del color del iris- Observation distance, which influences the appearance of the iris color

Las imagenes en 3D de los ojos del paciente y de su cara seran generadas a partir de fotograflas de alta definition y resolution.The 3D images of the patient's eyes and face will be generated from high definition and resolution photographs.

Ventajas tecnicas que aporta la inventionTechnical advantages provided by the invention

El invento aporta grandes ventajas en la prediccion y simulacion del resultado final tras la iridoplastia laser. Estas son:The invention provides great advantages in the prediction and simulation of the final result after laser iridoplasty. These are:

- Calculo matematico del porcentaje de probabilidad en la obtencion de los diferentes tipos de resultados esteticos.- Mathematical calculation of the percentage of probability in the obtaining of the different types of aesthetic results.

- Alta fiabilidad de prediccion, al tener en cuenta el fenotipo y el genotipo del paciente. - Alta congruencia de prediccion al basarse los calculos en la "Teona de los dos genes del color de ojos".- High prediction reliability, taking into account the patient's phenotype and genotype. - High prediction congruence when the calculations are based on the "Theona of the two genes of the eye color".

- Alta fidelidad de la prediccion estetica al usar una base de datos con imagenes reales de pacientes ya tratados con el mismo fenotipo y genotipo.- High fidelity of the aesthetic prediction when using a database with real images of patients already treated with the same phenotype and genotype.

- Alta precision de la prediccion estetica al emplear una base de datos con imagenes reales de pacientes ya tratados con los mismos tipos de laser.- High accuracy of the aesthetic prediction when using a database with real images of patients already treated with the same types of laser.

- Prediccion real de la influencia de la iluminacion ambiental en el tamano de las pupilas y la apariencia del color de los ojos. - Real prediction of the influence of environmental lighting on the size of the pupils and the appearance of the color of the eyes.

- Prediction real de la influencia de la distancia de observation en relation a la apariencia del color de los ojos.- Real prediction of the influence of the observation distance in relation to the appearance of the color of the eyes.

Ejemplo de realizationRealization example

Como ejemplo ponemos un paciente varon de nivel de pigmentation de grado 2 (Fig 4) segun la clasificacion de Grimaldos (Fig 1), con color de piel clara y color de cabello rubio, cuyo padre tiene ojos azules, color de piel clara y color de cabello castano, y cuya madre tiene ojos marrones, color de piel clara y color de cabello rubio.As an example we put a male patient of pigmentation level of grade 2 (Fig 4) according to the classification of Grimaldos (Fig 1), with clear skin color and blond hair color, whose father has blue eyes, light skin color and color of brown hair, and whose mother has brown eyes, light skin color and blond hair color.

Una vez procesados estos datos del fenotipo del paciente y de sus padres con el software especlfico de prediction del resultado tras la iridoplastia laser, obtenemos de forma automatica la siguiente prediction:Once processed these data of the patient's phenotype and their parents with the specific software of prediction of the result after the laser iridoplasty, we obtain automatically the following prediction:

- Color de ojos azul en un 75% con tono muy claro (Fig 5)- 75% blue eye color with very light tone (Fig 5)

- Color de ojos verde en un 25% con tono muy claro (Fig 6)- Eye color green by 25% with very light tone (Fig 6)

Para realizar la simulation del resultado estetico capturamos fotograflas de alta resolution de los ojos y de la cara del paciente, que procesaremos con el software especlfico de simulation de resultados. En el paciente que hemos puesto como ejemplo de realization obtenemos la siguiente simulation:To perform the simulation of the aesthetic result we capture high resolution photographs of the eyes and the patient's face, which we will process with the specific simulation software of results. In the patient that we have set as an example of realization, we obtain the following simulation:

- Modelo interactivo del ojo en tres dimensiones (3D) (Fig 7), en el que podemos cambiar su color y tono segun la paleta de colores de la Escala de colores de Grimaldos (Fig 3). - Modelo interactivo del ojo en tres dimensiones (3D), en el que podemos cambiar la iluminacion ambiental y observar los cambios del tamano de la pupila y de la apariencia del color y tono. Con alta iluminacion observamos en la Fig 8 el ojo con pupila pequena y color brillante. Con iluminacion moderada observamos en la Fig 9 el ojo con pupila intermedia y color menos brillante. Y con iluminacion baja observamos en la Fig 10 el ojo con pupila grande y color apagado.- Interactive model of the eye in three dimensions (3D) (Fig 7), in which we can change its color and tone according to the color palette of the Grimaldos Color Scale (Fig 3). - Interactive model of the eye in three dimensions (3D), in which we can change the environmental lighting and observe the changes in the size of the pupil and the appearance of color and tone. With high illumination we observe in Fig 8 the eye with small pupil and bright color. With moderate illumination we observed in Fig 9 the eye with intermediate pupil and less bright color. And with low illumination we observe in Fig 10 the eye with a large pupil and a dull color.

- Modelo interactivo de la cara del paciente en tres dimensiones (3D), en el que podemos cambiar la distancia de observation. En una distancia corta de primer plano observamos en la Fig 11 los ojos con pupila pequena y color brillante. Y a larga distancia observamos en la Fig 12 los ojos sin poder discriminar el tamano de la pupila y con color apagado.- Interactive model of the patient's face in three dimensions (3D), in which we can change the observation distance. In a short close-up distance we observe in Fig 11 the eyes with small pupil and bright color. And at long distance we observe in Fig 12 the eyes without being able to discriminate the size of the pupil and with dull color.

Description de las figurasDescription of the figures

Figura 1.- Clasificacion de pigmentation del iris de Grimaldos:Figure 1.- Classification of pigmentation of the iris of Grimaldos:

1- Grado 1: Muy baja concentration de pigmento1- Grade 1: Very low pigment concentration

2- Grado 2: Baja concentration de pigmento2- Grade 2: Low pigment concentration

3- Grado 3: Media concentration de pigmento3- Grade 3: Pigment medium concentration

4- Grado 4: Alta concentration de pigmento4- Grade 4: High pigment concentration

Figura 2.- Ejemplo de prediction de resultado:Figure 2.- Example of result prediction:

Ojo de color verde y tono claro Eye of green color and light tone

Figura 3.- Escala de 60 colores de iris de Grimaldos:Figure 3.- Scale of 60 colors of iris of Grimaldos:

1- Gama de colores marrones (20)1- Range of brown colors (20)

2- Gama de colores verdes (20)2- Green color range (20)

3- Gama de colores azules (20)3- Range of blue colors (20)

Figura 4.- Ejemplo de paciente con grado 2 de pigmentacion Figura 5.- Prediccion de ojo azul muy claro (75% de probabilidad) Figura 6.- Prediccion de ojo verde muy claro (75% de probabilidad) Figura 7.- Modelo interactivo tridimensional del ojoFigure 4.- Example of patient with grade 2 of pigmentation Figure 5.- Prediction of very light blue eye (75% probability) Figure 6.- Prediction of very light green eye (75% probability) Figure 7.- Interactive model three-dimensional eye

Figura 8.- Efecto visual de la prediccion con alta iluminacion:Figure 8.- Visual effect of the prediction with high illumination:

Pupila pequena y Color brillanteSmall pupil and bright color

Figura 9.- Efecto visual de la prediccion con iluminacion media:Figure 9.- Visual effect of the prediction with medium illumination:

Pupila intermedia y Color menos brillanteIntermediate pupil and less bright color

Figura 10.- Efecto visual de la prediccion con baja iluminacion:Figure 10.- Visual effect of the prediction with low illumination:

Pupila grande y Color oscuroLarge pupil and dark color

Figura 11.- Efecto visual de prediccion a corta distancia:Figure 11.- Visual effect of prediction at close range:

Pupila pequena y Color brillanteSmall pupil and bright color

Figura 12.- Efecto visual de prediccion a larga distancia:Figure 12.- Visual effect of long distance prediction:

Tamano de pupila no apreciable y Color oscuro Pupil size not appreciable and Dark color

Claims (10)

REIVINDICACIONES 1. Sistema automatico de prediction de resultados tras iridoplastias laser (tratamientos con laser del iris). El invento consta de:1. Automatic system of prediction of results after laser iridoplasties (laser treatments of the iris). The invention consists of: - Programa informatico de prediction de resultados basado en la "Teona de los dos genes del color de ojos".- Computer program of prediction of results based on the "Theon of the two genes of the eye color". - Programa informatico de prediction de resultados que utiliza la clasificacion de pigmentation de iris de Grimaldos.- Computer program of prediction of results that uses the classification of pigmentation of iris of Grimaldos. - Programa informatico de prediction de resultados que se utiliza los rasgos personales y familiares de fenotipo: color de ojos, grado de pigmentation ocular, color de piel y color de cabello.- Computer program of prediction of results that uses personal and family characteristics of phenotype: eye color, degree of ocular pigmentation, skin color and hair color. - Programa informatico de prediction de resultados que utiliza una base de imagenes reales de pacientes ya tratados con los mismos rasgos de fenotipo.- Computer program of prediction of results that uses a base of real images of patients already treated with the same phenotype traits. - Programa informatico de prediction de resultados que utiliza una base de imagenes reales de pacientes ya tratados con los mismos tipos de laser.- Computer program of prediction of results that uses a base of real images of patients already treated with the same types of laser. - Programa informatico de prediction de resultados que calcula los porcentajes de probabilidad de obtencion de los diferentes tipos de resultado cosmetico.- Computer program of prediction of results that calculates the percentages of probability of obtaining the different types of cosmetic result. 2. Sistema automatico de prediction de resultados tras iridoplastias laser segun revindication 1, que utiliza cualquier teorla de herencia del color de los ojos.2. Automatic system of prediction of results after laser iridoplasties according to revindication 1, which uses any inheritance theory of the color of the eyes. 3. Sistema automatico de prediction de resultados tras iridoplastias laser segun reivindicaciones 1 y 2, que utiliza cualquier tipo de clasificacion de grado de pigmentation del iris.3. Automatic system of prediction of results after laser iridoplasties according to claims 1 and 2, which uses any type of grade of pigmentation of the iris. 4. Sistema automatico de prediction de resultados tras iridoplastias laser segun reivindicaciones 1, 2 y 3, que utiliza cualquier tipo de rasgo de fenotipo o genotipo, personal o familiar.4. Automatic system of prediction of results after laser iridoplasties according to claims 1, 2 and 3, which uses any type of phenotype or genotype trait, personal or family. 5. Sistema automatico de prediction de resultados tras iridoplastias laser segun reivindicaciones 1, 23 y 4, que no utiliza imagenes reales de pacientes ya tratados, sino que usa imagenes artificiales generadas por ordenador.5. Automatic system of prediction of results after laser iridoplasties according to claims 1, 23 and 4, which does not use real images of patients already treated, but uses artificial images generated by computer. 6. Sistema automatico de prediction de resultados tras iridoplastias laser segun reivindicaciones 1, 2, 3, 4 y 5, que no calcula porcentajes de probabilidad.6. Automatic system of prediction of results after laser iridoplasties according to claims 1, 2, 3, 4 and 5, which does not calculate probability percentages. 7. Sistema automatico de simulation de resultados tras iridoplastias laser (tratamientos con laser del iris). El invento consta de:7. Automatic simulation of results after laser iridoplasties (laser treatments of the iris). The invention consists of: - Programa informatico de simulation de resultados que genera un modelo interactivo tridimensional del ojo y la cara.- Computer simulation of results program that generates a three-dimensional interactive model of the eye and face. - Programa informatico de simulation de resultados que utiliza una paleta de colores basada en la "Escala de 60 colores de Grimaldos".- Computer simulation of results program that uses a color palette based on the "Grimaldos 60-color scale". - Programa informatico de simulation de resultados que calcula la influencia de la iluminacion ambiental en el tamano de la pupila y el color del ojo. - Computer program of simulation of results that calculates the influence of environmental lighting on the size of the pupil and the color of the eye. - Programa informatico de simulation de resultados que calcula la influencia de la distancia de observation en la apariencia cosmetica de los ojos.- Computer simulation of results program that calculates the influence of observation distance on the cosmetic appearance of the eyes. - Sistema de captura de fotografias de alta resolution de los ojos y de la cara del paciente.- High resolution photo capture system of the patient's eyes and face. 8. Sistema automatico de simulation de resultados tras iridoplastias laser segun revindication 7, que genera cualquier tipo de modelo del ojo y la cara, bidimensional o tridimensional, de un ojo, de dos ojos, de la cara, de tipo interactivo o no.8. Automatic system of simulation of results after laser iridoplasties according to revindication 7, which generates any type of eye and face model, two-dimensional or three-dimensional, of an eye, of two eyes, of the face, interactive or not. 9. Sistema automatico de simulation de resultados tras iridoplastias laser segun revindication 7 y 8, que utiliza cualquier tipo de paleta de colores o clasificacion de colores.9. Automatic system of simulation of results after laser iridoplasties according to revindication 7 and 8, which uses any type of color palette or color classification. 10. Sistema automatico de simulation de resultados tras iridoplastias laser segun reivindicaciones 7, 8 y 9, que utiliza cualquier factor pueda influir en la apariencia cosmetica. II.Sistema automatico de simulation de resultados tras iridoplastias laser segun reivindicaciones 7, 8, 9 y 10, que utiliza cualquier modo de captura de las imagenes de los ojos y la cara, fotografia, video, camaras web, camaras infrarrojas, etc. 10. Automatic system of simulation of results after laser iridoplasties according to claims 7, 8 and 9, which uses any factor that may influence the cosmetic appearance. II. Automatic system of simulation of results after laser iridoplasties according to claims 7, 8, 9 and 10, which uses any mode of capture of the images of the eyes and face, photography, video, web cameras, infrared cameras, etc.
ES201700758A 2017-11-02 2017-11-02 System of prediction and simulation of results after laser iridoplasties (laser treatments of the iris) (Machine-translation by Google Translate, not legally binding) Withdrawn ES2711658A1 (en)

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ES201700758A ES2711658A1 (en) 2017-11-02 2017-11-02 System of prediction and simulation of results after laser iridoplasties (laser treatments of the iris) (Machine-translation by Google Translate, not legally binding)
PCT/ES2018/070703 WO2019086741A2 (en) 2017-11-02 2018-10-30 Method for predicting the aesthetic result of cosmetic laser iridoplasty

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Citations (5)

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Publication number Priority date Publication date Assignee Title
US20010012933A1 (en) * 2000-02-03 2001-08-09 Homer Gregg S. Method for alteration of iris pigmentation
US20050049584A1 (en) * 2001-02-02 2005-03-03 Lumineyes, Llc Techniques for alteration of iris pigment
US20070213693A1 (en) * 2004-08-27 2007-09-13 Ellex Medical Pty Ltd Selective ophthalmic laser treatment
US20110312534A1 (en) * 2010-03-05 2011-12-22 Erasmus University Medical Center Rotterdam Method for prediction of human iris color
WO2018033727A1 (en) * 2016-08-16 2018-02-22 Stroma Medical Corporation Method and apparatus for prediction of post-operative perceived iris color

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GB201408687D0 (en) * 2014-05-16 2014-07-02 Univ Leuven Kath Method for predicting a phenotype from a genotype

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US20010012933A1 (en) * 2000-02-03 2001-08-09 Homer Gregg S. Method for alteration of iris pigmentation
US20050049584A1 (en) * 2001-02-02 2005-03-03 Lumineyes, Llc Techniques for alteration of iris pigment
US20070213693A1 (en) * 2004-08-27 2007-09-13 Ellex Medical Pty Ltd Selective ophthalmic laser treatment
US20110312534A1 (en) * 2010-03-05 2011-12-22 Erasmus University Medical Center Rotterdam Method for prediction of human iris color
WO2018033727A1 (en) * 2016-08-16 2018-02-22 Stroma Medical Corporation Method and apparatus for prediction of post-operative perceived iris color

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Title
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NÜTZI C. ET AL. Predictability of morphological changes of the anterior chamber angle after iridotomy by ultrasound biomicroscopy. Klinische Monatsblatter für Augenheilkunde, 04/2015, Vol. 232, Páginas 419-426 *

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