ES2709031A1 - Vegetable oil for food use fortified with vitamin D3 (Machine-translation by Google Translate, not legally binding) - Google Patents
Vegetable oil for food use fortified with vitamin D3 (Machine-translation by Google Translate, not legally binding) Download PDFInfo
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings or cooking oils characterised by ingredients other than fatty acid triglycerides
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Health & Medical Sciences (AREA)
- Nutrition Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Description
DESCRIPCIONDESCRIPTION
Aceite vegetal de uso alimentario fortificado con vitamina D3.Vegetable oil for food use fortified with vitamin D3.
Sector de la tecnicaSector of the technique
Alimentacion. La presente invencion se refiere a un aceite vegetal de uso alimentario, habitualmente aceite de oliva, fortificado con vitamina D3 (colecalciferol), a una concentration sencilla, identificable y significativa, siendo la fuente de vitamina D3 variable y tambien apta para veganos.Feeding. The present invention relates to a vegetable oil for food use, usually olive oil, fortified with vitamin D3 (cholecalciferol), at a simple, identifiable and significant concentration, the source of vitamin D3 being variable and also suitable for vegans.
Antecedentes de la invencionBackground of the invention
El deficit de vitamina D es una epidemia a nivel mundial, y ha sido descrito en ninos, jovenes, adultos, mujeres gestantes y postmenopausicas, ancianos y por supuesto, en sujetos con osteoporosis.Vitamin D deficiency is an epidemic worldwide, and has been described in children, youth, adults, pregnant and postmenopausal women, the elderly and of course, in subjects with osteoporosis.
El deficit cllnico de vitamina D caracterizado por hipocalcemia y/o hipofosfatemia, raquitismo y osteomalacia en ninos, y osteomalacia en adultos es raro en palses desarrollados. Sin embargo, la deficiencia subcllnica es muy frecuente. El grupo de trabajo de Osteoporosis y Metabolismo mineral de la Sociedad Espanola de Endocrinologla y Nutrition (informe del ano 2017) reporta que "en individuos mayores de 65 anos se han descrito concentraciones de vitamina D (25OH vitamina D) por debajo de 20 ng/mL en un 80-100% de las personas y en poblacion menor de 65 anos el deficit alcanza a un 40 % de la poblacion espanola”.The clinical deficit of vitamin D characterized by hypocalcemia and / or hypophosphatemia, rickets and osteomalacia in children, and osteomalacia in adults is rare in developed countries. However, subclinical deficiency is very frequent. The working group of Osteoporosis and Mineral Metabolism of the Spanish Society of Endocrinology and Nutrition (report of the year 2017) reports that "in individuals over 65 years have been described concentrations of vitamin D (25OH vitamin D) below 20 ng / mL in 80-100% of the people and in a population under 65 years the deficit reaches 40% of the Spanish population ".
La carencia de vitamina D se asocia a osteoporosis, debilidad muscular con aumento del riesgo de caldas y posibilidad de fracturas. A dla de hoy, tambien se estan estudiando posibles efectos beneficiosos sobre la inmunidad, el cancer y el sistema cardiovascular.Vitamin D deficiency is associated with osteoporosis, muscle weakness with increased calda risk and the possibility of fractures. Today, we are also studying possible beneficial effects on immunity, cancer and the cardiovascular system.
Desde hace unos anos, los niveles de vitamina D (25OH vitamina D) son facilmente cuantificables con una analltica de rutina. Se considera que existe deficit por debajo de 20-30 ng/mL y la evidencia cientlfica muestra que hay que tener un mlnimo de 20 ng/mL para garantizar la salud osea.For a few years, the levels of vitamin D (25OH vitamin D) are easily quantifiable with a routine analysis. It is considered that there is a deficit below 20-30 ng / mL and the scientific evidence shows that it is necessary to have a minimum of 20 ng / mL to guarantee bone health.
La ingesta diaria recomendada por las distintas sociedades cientlficas es de 600 unidades internacionales (Ul) de vitamina D en menores de 70 anos y de 800 Ul para mayores de 70 anos. Es importante recalcar que esta ingesta es la recomendada para personas sanas, y probablemente sea mayor en sujetos con enfermedades que asocien deficit. El llmite superior de seguridad es de 4000 Ul al dla (Institute of Medicine, 2010).The daily intake recommended by the different scientific societies is 600 international units (Ul) of vitamin D in children under 70 years of age and 800 UI for people over 70 years of age. It is important to emphasize that this intake is recommended for healthy people, and probably higher in subjects with diseases that associate deficit. The upper limit of safety is 4000 IU per day (Institute of Medicine, 2010).
En el ser humano, el principal aporte proviene de la transformation cutanea del 7-dehidrocolesterol en colecalciferol por action de los rayos ultravioleta solares. La vitamina D tambien puede obtenerse a partir de los alimentos, tanto de origen animal (colecalciferol o vitamina D3) como de origen vegetal (ergocalciferol o vitamina D2). No obstante, la mayorla de los alimentos tienen escasas cantidades.In humans, the main contribution comes from the cutaneous transformation of 7-dehydrocholesterol in colecalciferol by the action of solar ultraviolet rays. Vitamin D can also be obtained from foods, both animal (colecalciferol or vitamin D3) and plant origin (ergocalciferol or vitamin D2). However, most foods have low amounts.
Resulta paradojico que en palses soleados como Espana exista tal grado de insuficiencia/deficiencia de "la vitamina del sol”, pero la mayor parte de nuestro pais esta por encima del paralelo 35 norte, donde la posibilidad de sintetizar vitamina D es escasa durante la mayor parte del ano. En verano, las altas temperaturas limitan la exposition solar, especialmente en personas mayores. El necesario empleo de fotoprotectores asimismo tambien limita la production cutanea. El resultado es que la carencia dietetica no se compensa con la slntesis cutanea como cabrla esperar, con lo que con relativa frecuencia se precisa la suplementacion. It is paradoxical that in sunny countries like Spain there is such a degree of insufficiency / deficiency of "the sun's vitamin", but most of our country is above the northern 35th parallel, where the possibility of synthesizing vitamin D is scarce during the greater In the summer, high temperatures limit solar exposure, especially in older people.The necessary use of sunscreens also limits the skin production.The result is that the dietary deficiency is not compensated with the skin synthesis as expected, with which relatively often supplementation is required.
El problema de dicha suplementacion farmacologica reside en las altas tasas de abandono. El sujeto a menudo es reacio a tomar una pastilla casi de por vida "sin estar enfermo” -el escollo de la prevencion primaria-.The problem of such pharmacological supplementation lies in the high dropout rates. The subject is often reluctant to take a pill almost for life "without being sick" -the pitfall of primary prevention.
Una manera de mejorar el estado de salud serla a traves de la fortificacion de alimentos de consumo habitual, como ocurrio en su dla con la sal yodada para la prevencion del bocio.One way to improve the state of health would be through the fortification of foods of habitual consumption, as occurred in the day with iodized salt for the prevention of goitre.
En nuestro pals el aceite de oliva es de consumo habitual y no se asocia con alergias o intolerancias alimentarias a diferencia de los lacteos, principal fuente de enriquecimiento de vitamina D en la dieta. Ademas, este alimento ha demostrado numerosas propiedades beneficiosas para la salud. El aceite de oliva no tiene vitamina D sino se adiciona. (Moreiras O, Carbajal A, Cabrera L, Cuadrado C. Tablas de composition de alimentos. Ediciones Piramide (Grupo Anaya, SA). 18a edition. 2016.)In our country, olive oil is commonly consumed and is not associated with food allergies or intolerances, unlike dairy products, the main source of vitamin D enrichment in the diet. In addition, this food has shown numerous beneficial properties for health. Olive oil does not have vitamin D but is added. (Moreiras O, Carbajal A, Cabrera L, Square C. Tables of food composition, Piramide Ediciones (Grupo Anaya, SA), 18th edition, 2016.)
La vitamina D es liposoluble, por lo que presenta compatibilidad bioqulmica con los aceites (grasas).Vitamin D is liposoluble, so it has biochemical compatibility with oils (fats).
La fortificacion del aceite vegetal de uso alimentario de modo que la concentration de vitamina D3 por mL de aceite sea significativa, evidente y entendible por el consumidor es necesaria, podrla eliminar las barreras anteriormente nombradas y facilitarla el mantenimiento de unas concentraciones de vitamina D estables en el tiempo. De este modo, tambien se facilitarla el ajuste de dosis por el facultativo que solicita los niveles sangulneos de este micronutriente. La vitamina D3 se obtiene habitualmente a partir de la lana de las ovejas. Este producto no es aceptable para un vegano, ni tampoco para un vegetariano si el animal ha sido sacrificado. Es posible obtener vitamina D3 de los llquenes. Estos organismos consisten tradicionalmente en la asociacion, simbiosis, entre un hongo y un alga, por lo que son aptos para veganos y vegetarianos. La vitamina D3 obtenida a partir de llquenes es tambien un producto Kosher, y valido para la religion musulmana. No contiene gluten, ni lactosa ni fructosa.The fortification of vegetable oil for food use so that the concentration of vitamin D3 per mL of oil is significant, evident and understandable by the consumer is necessary, could eliminate the above-mentioned barriers and facilitate the maintenance of stable vitamin D concentrations in time. In this way, dose adjustment by the physician requesting the blood levels of this micronutrient is also facilitated. Vitamin D3 is usually obtained from the wool of sheep. This product is not acceptable for a vegan, nor for a vegetarian if the animal has been slaughtered. It is possible to obtain vitamin D3 from the lichens. These organisms traditionally consist of the association, symbiosis, between a fungus and an alga, so they are suitable for vegans and vegetarians. Vitamin D3 obtained from lichens is also a Kosher product, and valid for the Muslim religion. It does not contain gluten, lactose or fructose.
En la literatura, existen patentados varios aceites funcionales que contienen una mezcla de vitaminas, grasas y otros compuestos. No se han encontrado publicaciones de aceites comestibles solo con vitamina D3 y apta para todos los publicos.In the literature, there are several patented functional oils that contain a mixture of vitamins, fats and other compounds. No publications of edible oils only with vitamin D3 have been found and suitable for all audiences.
En la patente WO 2004/066754 se anade a un aceite comestible un preparado multivitamlnico consistente en vitamina D3, vitamina K1 y vitamina B6. No se cita la fuente de vitamina D3 (animal/vegetal) y respecto a la cantidad, tan solo se concreta "no menos de 0.5 pg por cada 1000 mL de aceite”, cantidad “homeopatica” de 20 Ul/ 1000 mL de aceite.In WO 2004/066754 a multivitamin preparation consisting of vitamin D3, vitamin K1 and vitamin B6 is added to an edible oil. The source of vitamin D3 (animal / vegetable) is not mentioned and regarding quantity, only "no less than 0.5 pg per 1000 mL of oil", "homeopathic" amount of 20 IU / 1000 mL of oil, is specified.
La P200930364 se refiere a una mezcla de aceites funcionales a base de aceite de oliva, a los que se anaden compuestos bioactivos: isoflavonas de soja; coenzima Q-10 (ubiquinona); vitamina E; vitamina D; licopeno; vitamina K; vitamina A; omega 3 EPA, omega 3 DHA y sus mezclas. Se refiere que puede contener vitamina D, colecalciferol, sin especificar su origen en cantidades entre 0-5 pg/100 mL (maximo 200 UI/100 mL), escasas como suplemento dietetico requerido para cubrir las necesidades diarias en sujetos con carencia de esta vitamina. Posteriormente, se hace referencia a una dosis de vitamina D (colecalciferol) de 2.4 pg, se desconoce en que volumen.P200930364 refers to a mixture of functional oils based on olive oil, to which are added bioactive compounds: soy isoflavones; Coenzyme Q-10 (ubiquinone); Vitamin E; vitamin D; lycopene; vitamin K; Vitamin A; omega 3 EPA, omega 3 DHA and their mixtures. It is said that it may contain vitamin D, cholecalciferol, without specifying its origin in quantities between 0-5 pg / 100 mL (maximum 200 IU / 100 mL), scarce as a dietary supplement required to cover daily needs in subjects with vitamin deficiency. . Subsequently, reference is made to a dose of vitamin D (cholecalciferol) of 2.4 pg, it is unknown in what volume.
Explication de la inventionExplanation of the invention
Partiendo de un aceite vegetal comestible, preferiblemente de las mejores propiedades para la salud, como por ejemplo, el aceite de oliva virgen extra, se le anade vitamina D3 apta para vegetarianos, y con posibilidad de emplear en su lugar vitamina D3 apta para veganos (obtenida a partir de llquenes). Starting from an edible vegetable oil, preferably of the best health properties, such as extra virgin olive oil, is added vitamin D3 suitable for vegetarians, and with the possibility of using instead vitamin D3 suitable for vegans ( obtained from lions).
1 microgramo (pg) de vitamina D3 equivale a 40 unidades internacionales (Ul).1 microgram (pg) of vitamin D3 equals 40 international units (Ul).
Se establece una concentration sencilla: "cada 10 mL de aceite contienen 100 Ul de vitamina D3”.A simple concentration is established: "every 10 mL of oil contains 100 IU of vitamin D3".
Tradicionalmente, la equivalencia de volumenes en recipientes es: 1 cucharada = 1 cucharada de las soperas = 15 mL y 1 cucharadita = 1 cucharada de las de postre = 5 mL. De manera que 30 mL de aceite (2 cucharadas "soperas”) cubren el 50% de los requerimientos diarios de vitamina D en poblacion sana (el consumo de aceite de oliva per capita medio de un espanol es de 8-10 L/ano, de 22 mL a 27 mL al dla). Se pueden necesitar mayores dosis de vitamina D3 para sujetos con osteoporosis, mala absorcion, obesidad, muy poca exposition solar, etc.Traditionally, the equivalence of volumes in containers is: 1 tablespoon = 1 tablespoon of tureens = 15 mL and 1 teaspoon = 1 tablespoon of dessert = 5 mL. So that 30 mL of oil (2 tablespoons "tureens") cover 50% of the daily requirements of vitamin D in a healthy population (the average olive oil consumption per capita of a Spaniard is 8-10 L / year, from 22 mL to 27 mL per day). Higher doses of vitamin D3 may be needed for subjects with osteoporosis, poor absorption, obesity, very little sun exposure, etc.
La vitamina D forma parte de las vitaminas liposolubles, naturaleza que garantiza el buen comportamiento qulmico en la mezcla. Ademas, comparte con el aceite las mismas injurias en cuanto a exposicion a la luz y agentes oxidantes. El packaging y almacenamiento sera el mas conveniente para el aceite de oliva. Vitamin D is part of the liposoluble vitamins, nature that guarantees the good chemical behavior in the mixture. In addition, it shares with the oil the same insults in terms of exposure to light and oxidizing agents. The packaging and storage will be the most convenient for olive oil.
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