ES2701975R1 - Uso de ligandos del receptor sigma en el dolor post-herpetico - Google Patents

Uso de ligandos del receptor sigma en el dolor post-herpetico

Info

Publication number
ES2701975R1
ES2701975R1 ES201990008A ES201990008A ES2701975R1 ES 2701975 R1 ES2701975 R1 ES 2701975R1 ES 201990008 A ES201990008 A ES 201990008A ES 201990008 A ES201990008 A ES 201990008A ES 2701975 R1 ES2701975 R1 ES 2701975R1
Authority
ES
Spain
Prior art keywords
post
herpetic pain
sigma receiver
ligands
receiver ligands
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
ES201990008A
Other languages
English (en)
Spanish (es)
Other versions
ES2701975A2 (es
Inventor
Jesús Cebrecos-Perez
Carlos Ramón Plata-Salaman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Esteve Pharmaceuticals SA
Original Assignee
Esteve Pharmaceuticals SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Esteve Pharmaceuticals SA filed Critical Esteve Pharmaceuticals SA
Publication of ES2701975A2 publication Critical patent/ES2701975A2/es
Publication of ES2701975R1 publication Critical patent/ES2701975R1/es
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/18—One oxygen or sulfur atom
    • C07D231/20—One oxygen atom attached in position 3 or 5
    • C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES201990008A 2016-07-12 2017-07-11 Uso de ligandos del receptor sigma en el dolor post-herpetico Withdrawn ES2701975R1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16382331 2016-07-12
PCT/EP2017/067332 WO2018011169A1 (fr) 2016-07-12 2017-07-11 Utilisation de ligands des récepteurs sigma contre la douleur post-herpétique.

Publications (2)

Publication Number Publication Date
ES2701975A2 ES2701975A2 (es) 2019-02-26
ES2701975R1 true ES2701975R1 (es) 2019-03-01

Family

ID=56418477

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201990008A Withdrawn ES2701975R1 (es) 2016-07-12 2017-07-11 Uso de ligandos del receptor sigma en el dolor post-herpetico

Country Status (4)

Country Link
AR (1) AR109024A1 (fr)
ES (1) ES2701975R1 (fr)
TW (1) TW201806601A (fr)
WO (1) WO2018011169A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020113094A1 (fr) 2018-11-30 2020-06-04 Nuvation Bio Inc. Composés pyrrole et pyrazole et leurs procédés d'utilisation

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006021462A1 (fr) * 2004-08-27 2006-03-02 Laboratorios Del Dr. Esteve, S.A. Inhibiteurs de récepteur sigma
WO2012156497A1 (fr) * 2011-05-19 2012-11-22 Laboratorios Del Dr. Esteve, S.A. Utilisation de ligands sigma dans une douleur associée au diabète de type 2
WO2016096125A1 (fr) * 2014-12-15 2016-06-23 Laboratorios Del Dr. Esteve, S.A. Utilisation de ligands des récepteurs sigma dans l'arthrose

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2586212T3 (es) 2010-02-04 2016-10-13 Laboratorios Del Dr. Esteve, S.A. Polimorfos y solvatos de clorhidrato de 4-[2-[[5-metil-1-(2-naftalenil)-1H-pirazol-3-il]oxi]etil]morfolina
EP2460519A1 (fr) * 2010-12-03 2012-06-06 Laboratorios Del. Dr. Esteve, S.A. Utilisation de ligands sigma pour la douleur du cancer des os

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006021462A1 (fr) * 2004-08-27 2006-03-02 Laboratorios Del Dr. Esteve, S.A. Inhibiteurs de récepteur sigma
WO2012156497A1 (fr) * 2011-05-19 2012-11-22 Laboratorios Del Dr. Esteve, S.A. Utilisation de ligands sigma dans une douleur associée au diabète de type 2
WO2016096125A1 (fr) * 2014-12-15 2016-06-23 Laboratorios Del Dr. Esteve, S.A. Utilisation de ligands des récepteurs sigma dans l'arthrose

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
S L COLLINS ET AL. Antidepressants and anticonvulsants for diabetic neuropathy and postherpetic neuralgia. Journal of Pain and Sympton Management, 2000, Vol. 20, Páginas 449-458 resumen, páginas 453-454, tabla 1 *

Also Published As

Publication number Publication date
TW201806601A (zh) 2018-03-01
ES2701975A2 (es) 2019-02-26
AR109024A1 (es) 2018-10-17
WO2018011169A1 (fr) 2018-01-18

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