ES2693177R1 - Procedimiento para la obtención de secoiridoides dialdehídicos - Google Patents

Procedimiento para la obtención de secoiridoides dialdehídicos

Info

Publication number
ES2693177R1
ES2693177R1 ES201830049A ES201830049A ES2693177R1 ES 2693177 R1 ES2693177 R1 ES 2693177R1 ES 201830049 A ES201830049 A ES 201830049A ES 201830049 A ES201830049 A ES 201830049A ES 2693177 R1 ES2693177 R1 ES 2693177R1
Authority
ES
Spain
Prior art keywords
secoiridoids
procedure
dialdehyde
obtaining
obtaining dialdehyde
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES201830049A
Other languages
English (en)
Other versions
ES2693177B1 (es
ES2693177A2 (es
Inventor
Guzman José María Fernandez-Bolanos
Castilla Inés Maya
Benjumea Alejandro Gonzalez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad de Sevilla
Original Assignee
Universidad de Sevilla
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad de Sevilla filed Critical Universidad de Sevilla
Priority to ES201830049A priority Critical patent/ES2693177B1/es
Publication of ES2693177A2 publication Critical patent/ES2693177A2/es
Publication of ES2693177R1 publication Critical patent/ES2693177R1/es
Application granted granted Critical
Publication of ES2693177B1 publication Critical patent/ES2693177B1/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738Esters of keto-carboxylic acids or aldehydo-carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/222Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/317Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C07C67/327Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by elimination of functional groups containing oxygen only in singly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D309/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/32Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
ES201830049A 2017-03-10 2017-03-10 Procedimiento para la obtención de secoiridoides dialdehídicos Active ES2693177B1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES201830049A ES2693177B1 (es) 2017-03-10 2017-03-10 Procedimiento para la obtención de secoiridoides dialdehídicos

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES201830049A ES2693177B1 (es) 2017-03-10 2017-03-10 Procedimiento para la obtención de secoiridoides dialdehídicos

Publications (3)

Publication Number Publication Date
ES2693177A2 ES2693177A2 (es) 2018-12-07
ES2693177R1 true ES2693177R1 (es) 2019-02-20
ES2693177B1 ES2693177B1 (es) 2019-12-03

Family

ID=64480724

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201830049A Active ES2693177B1 (es) 2017-03-10 2017-03-10 Procedimiento para la obtención de secoiridoides dialdehídicos

Country Status (1)

Country Link
ES (1) ES2693177B1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3838885B1 (en) * 2019-12-16 2022-06-29 National and Kapodistrian University of Athens Process for the production of oleocanthal, oleacein and their analogues

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007081808A2 (en) * 2006-01-05 2007-07-19 Deviris Inc. Compounds and derivatives for the treatment of medical conditions by modulating hormone-sensitive lipase activity

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007081808A2 (en) * 2006-01-05 2007-07-19 Deviris Inc. Compounds and derivatives for the treatment of medical conditions by modulating hormone-sensitive lipase activity

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
GUISO, M. & MARRA, C. . HIGHLIGHTS IN OLEUROPEIN AGLYCONE STRUCTURE. Natural Product Research: Formerly Natural Product Letters , 2005, Vol. 19, Nº 2, Páginas 105-109 1478-6419; 1029-2349 (en línea), (DOI: 10.1080/14786410410001696147) Ver página 106, esquema 1; página 107, esquema 2. *
JERMAN KLEN, T. et al. . PHENOLIC PROFILING OF OLIVES AND OLIVE OIL PROCESS-DERIVED MATRICES USING UPLC-DAD-ESI-QTOF-HRMS ANALYSIS. Journal of Agricultural and Food Chemistry , 18.03.2015, Vol. 63, Nº 15, Páginas 3859-3872 0021-8561, (DOI: 10.1021/jf506345q) Ver página 3859, resumen; página 3865, tabla 3, estructura II. *
MASON, J.D. & MURPHREE, S.S. . MICROWAVE-ASSISTED AQUEOUS KRAPCHO DECARBOXYLATION. Synlett, 08.05.2013, Vol. 24, Nº 11, Páginas 1391-1394 1437-2096, (DOI: 10.1055/s-0033-1338701) Ver página 1391, resumen y columna 1, párrafo 1; esquemas 1 y 2. *
MONTEDORO, G. et al. . SIMPLE AND HYDROLYZABLE COMPOUNDS IN VIRGIN OLIVE OIL. 3. SPECTROSCOPIC CHARACTERIZATIONS OF THE SECOIRIDOID DERIVATIVES. Journal of Agricultural and Food Chemistry , 1993, Vol. 41, Nº 11, Páginas 2228-2234 0021-8561, (DOI: DOI: 10.1021/jf00035a076) Ver página 2228, resumen; página 2231, figura 3. *
NARDI, M. et. al. . BIOMIMETIC SYNTHESIS AND ANTIOXIDANT EVALUATION OF 3,4-DHPEA-EDA [2-(3,4-HYDROXYPHENYL) ETHYL (3S,4E)-4-FORMYL-3-(2-OXOETHYL)HEX-4-ENOATE. Food Chemistry , 13.04.2014, Vol. 162, Páginas 89-93 0308-8146, (DOI: 10.1016/j.foodchem.2014.04.015) Ver página 89, resumen; página 91, resultados y discusión; esquema 1. *
VOUGOGIANNOPOULOU, K. at al. . ONE-STEP SEMISYNTHESIS OF OLEACEIN AND THE . Journal of Natural Products, 25.02.2014, Vol. 77, Nº 3, Páginas 441-445 0163-3864, (DOI: 10.1021/np401010x) Ver página 441, resumen; página 442, columna 2, párrafos 3-4; figura 2; página 444, columna 2, párrafo 1.<br /> *

Also Published As

Publication number Publication date
ES2693177B1 (es) 2019-12-03
ES2693177A2 (es) 2018-12-07

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