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Novartis AG
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Ciba Geigy AG
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Publication of ES263315A1publicationCriticalpatent/ES263315A1/en
C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
C07C213/06—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton from hydroxy amines by reactions involving the etherification or esterification of hydroxy groups
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Chemical & Material Sciences
(AREA)
Organic Chemistry
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Chemical Kinetics & Catalysis
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Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Hydrogenated Pyridines
(AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
Obtaining secondary amines of the formula **FORMULA** where R means a low hydrocarbon residue, which in the carbon chain may also be interrupted by oxygen, and R1 a low hydrocarbon residue, and its salts. The low hydrocarbon residue R, optionally interrupted by oxygen, is first of all aliphatic in nature, for example a low oxaalkyl residue, such as the 4-oxa-pentyl- (1) residue, or preferably a straight, low alkyl residue or branched, for example methyl, ethyl, allyl, isopropyl, butyl, butyl sec., amyl, isoamyl or hexyl, first and foremost, however, n-propyl. As low hydrocarbon residues R1 are mentioned the finishes indicated, before all alkyl residues, such as methyl. The new compounds and their salts have an outstanding sympatholytic effect with a component of sedative and bradycardial efficacy. (Machine-translation by Google Translate, not legally binding)
ES0263315A1959-12-181960-12-17Procedure for the obtaining of new secondary amines (Machine-translation by Google Translate, not legally binding)
ExpiredES263315A1
(en)
Procedure for the obtaining of basically replaced propanols and obtaining alkenilamines from them by separation of water (Machine-translation by Google Translate, not legally binding)
Procedimine for the obtaining of derivatives of the acid p- [cumarinyl- (3)] - phenyl carbamine (Machine-translation by Google Translate, not legally binding)
Procedure for obtaining new derivatives of piperidil-2 phenylmethanols and their added salts (Machine-translation by Google Translate, not legally binding)
Procedure for the obtaining of new carbomids replaced in nitrogen atomo and in the atom of or of position b (Machine-translation by Google Translate, not legally binding)