ES2538719B1 - Racemasa BsrAb for amino acid racemization - Google Patents

Racemasa BsrAb for amino acid racemization Download PDF

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Publication number
ES2538719B1
ES2538719B1 ES201331890A ES201331890A ES2538719B1 ES 2538719 B1 ES2538719 B1 ES 2538719B1 ES 201331890 A ES201331890 A ES 201331890A ES 201331890 A ES201331890 A ES 201331890A ES 2538719 B1 ES2538719 B1 ES 2538719B1
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Prior art keywords
bsrab
racemasa
amino acid
racemization
amino acids
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Active
Application number
ES201331890A
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Spanish (es)
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ES2538719A1 (en
Inventor
Felipe Cava Valenciano
Akbar ESPAILLAT FERNÁNDEZ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universidad Autonoma de Madrid
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Universidad Autonoma de Madrid
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Racemasa BsrAb para la racemización de aminoácidos.#En la presente invención se incluye una racemasa de Acinetobacter baumannii (BsrAb) la cual presenta un amplio espectro de racemización y por tanto permite la obtención de L aminoácidos desde el enantiómero D y de D aminoácidos desde el enantiómero L. Por tanto la presente invención se refiere tanto al uso de dicha racemasa in vitro y también a un método de racemización de aminoácidos. Además la presente invención se refiere a un método de síntesis de muropéptidos.Racemasa BsrAb for the racemization of amino acids. # The present invention includes a racemase of Acinetobacter baumannii (BsrAb) which has a broad spectrum of racemization and therefore allows the obtaining of L amino acids from the enantiomer D and D amino acids from the enantiomer L. Thus the present invention relates both to the use of said racemase in vitro and also to an amino acid racemization method. In addition, the present invention relates to a method of synthesis of muropeptides.

Description

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Claims (1)

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ES201331890A 2013-12-20 2013-12-20 Racemasa BsrAb for amino acid racemization Active ES2538719B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES201331890A ES2538719B1 (en) 2013-12-20 2013-12-20 Racemasa BsrAb for amino acid racemization

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES201331890A ES2538719B1 (en) 2013-12-20 2013-12-20 Racemasa BsrAb for amino acid racemization

Publications (2)

Publication Number Publication Date
ES2538719A1 ES2538719A1 (en) 2015-06-23
ES2538719B1 true ES2538719B1 (en) 2016-05-12

Family

ID=53398590

Family Applications (1)

Application Number Title Priority Date Filing Date
ES201331890A Active ES2538719B1 (en) 2013-12-20 2013-12-20 Racemasa BsrAb for amino acid racemization

Country Status (1)

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ES (1) ES2538719B1 (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1489166A4 (en) * 2002-03-01 2006-04-05 Kyowa Hakko Kogyo Kk Amino acid racemase having low substrate specificity and process for producing racemic amino acid

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Publication number Publication date
ES2538719A1 (en) 2015-06-23

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