ES250529A1 - A procedure for the preparation of N-accidental derivatives of desulfoheparin (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of N-accidental derivatives of desulfoheparin (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES250529A1
ES250529A1 ES0250529A ES250529A ES250529A1 ES 250529 A1 ES250529 A1 ES 250529A1 ES 0250529 A ES0250529 A ES 0250529A ES 250529 A ES250529 A ES 250529A ES 250529 A1 ES250529 A1 ES 250529A1
Authority
ES
Spain
Prior art keywords
desulfoheparin
translation
preparation
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0250529A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR769596A external-priority patent/FR1333703A/en
Priority claimed from FR776294A external-priority patent/FR81302E/en
Priority claimed from FR781097A external-priority patent/FR81303E/en
Priority claimed from FR781914A external-priority patent/FR81304E/en
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Publication of ES250529A1 publication Critical patent/ES250529A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

Process for the preparation of N-acylated derivatives of N-desulfoheparin, characterized in particular by the fact that heparin is subjected to the action of a lower alcohol, is reacted on the ester forming an alkaline base; N-desulfoheparin is isolated by precipitation in a water-soluble solvent and by treatment of this by an acylating agent it is transformed into the N-acylated derivatives that are desired. (Machine-translation by Google Translate, not legally binding)
ES0250529A 1958-07-05 1959-07-04 A procedure for the preparation of N-accidental derivatives of desulfoheparin (Machine-translation by Google Translate, not legally binding) Expired ES250529A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR769596A FR1333703A (en) 1958-07-05 1958-07-05 Process for the preparation of nu-desulfo heparin and its acyl derivatives
FR776294A FR81302E (en) 1958-10-09 1958-10-09 Process for preparing nu-desulfoheparin and its acyl derivatives
FR781097A FR81303E (en) 1958-12-08 1958-12-08 Process for preparing nu-desulfoheparin and its acyl derivatives
FR781914A FR81304E (en) 1958-12-17 1958-12-17 Process for preparing nu-desulfoheparin and its acyl derivatives

Publications (1)

Publication Number Publication Date
ES250529A1 true ES250529A1 (en) 1959-12-01

Family

ID=27445091

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0250529A Expired ES250529A1 (en) 1958-07-05 1959-07-04 A procedure for the preparation of N-accidental derivatives of desulfoheparin (Machine-translation by Google Translate, not legally binding)

Country Status (5)

Country Link
BE (1) BE580372A (en)
CH (1) CH385812A (en)
ES (1) ES250529A1 (en)
NL (1) NL6407131A (en)
SE (1) SE310659B (en)

Also Published As

Publication number Publication date
SE310659B (en) 1969-05-12
CH385812A (en) 1964-12-31
NL6407131A (en) 1964-08-10
BE580372A (en) 1960-01-04

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